1. Emerging open-channel droplet arrays for biosensing.
- Author
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Song, Yongchao, Wang, Lirong, Xu, Tailin, Zhang, Guangyao, and Zhang, Xueji
- Subjects
SERS spectroscopy ,CELLULAR recognition - Abstract
Open-channel droplet arrays have attracted much attention in the fields of biochemical analysis, biofluid monitoring, biomarker recognition and cell interactions, as they have advantages with regard to miniaturization, parallelization, high-throughput, simplicity and accessibility. Such droplet arrays not only improve the sensitivity and accuracy of a biosensor, but also do not require sophisticated equipment or tedious processes, showing great potential in next-generation miniaturized sensing platforms. This review summarizes typical examples of open-channel microdroplet arrays and focuses on diversified biosensing integrated with multiple signal-output approaches (fluorescence, colorimetric, surface-enhanced Raman scattering (SERS), electrochemical, etc.). The limitations and development prospects of open-channel droplet arrays in biosensing are also discussed with regard to the increasing demand for biosensors. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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