5 results on '"Massafra U"'
Search Results
2. [Correlation between radiologic and ultrasonographic patterns and clinical manifestations in symptomatic hip osteoarthritis].
- Author
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Migliore A, Tormenta S, Iannessi F, Mascheroni E, Barbati E, Capuano A, Diaco M, Massafra U, Padalino C, Vacca F, Alimonti A, Martin LS, and Granata M
- Subjects
- Adjuvants, Immunologic therapeutic use, Adult, Aged, Aged, 80 and over, Algorithms, Female, Humans, Hyaluronic Acid therapeutic use, Injections, Intra-Articular, Longitudinal Studies, Male, Middle Aged, Osteoarthritis, Hip complications, Osteoarthritis, Hip drug therapy, Pain drug therapy, Pain etiology, Pain Measurement, Radiography, Severity of Illness Index, Treatment Outcome, Ultrasonography, Osteoarthritis, Hip diagnostic imaging
- Abstract
Increasing amounts of data have recently been published regarding ultrasonographic (US) findings of osteoarthritic joints, but very few data concern hip joints. In the current study we described US patterns concerning 490 patients affected by symptomatic hip osteoarthritis (OA) who underwent to intra-articular injections of hyaluronic products under US guidance. All patients were studied by US and X-ray of hip, clinical evaluation was assessed by the followings indexes: Lequesne, pain VAS, ICED, Global Physician Assessment and Global Patient Assessment. US findings were summarized in four main patterns, effusion and synovial proliferation were also detected. The aim of this study was to correlate US findings with clinical assessment and radiographic findings (according to Kellgren-Lawrence classification). Pearson's r correlation coefficient were computed and come out significant and positive between X ray and US patterns and between clinical indexes and US patterns. Also the correlation between K-L score and US patterns showed a significant positive correlation indicating that higher K-L scores are associated with increasing abnormal US findings. Our data suggest that ultrasonography of the hip may give useful information about the state of synovial membrane, synovial fluid, joint margins and bone profile in hip OA. Further studies are needed to evaluate their prevalence in hip OA symptomatic and not-symptomatic patients and their correlation to treatment outcome.
- Published
- 2007
- Full Text
- View/download PDF
3. [18-month observational study on efficacy of intraarticular hyaluronic acid (Hylan G-F 20) injections under ultrasound guidance in hip osteoarthritis].
- Author
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Migliore A, Tormenta S, Massafra U, Martin Martin LS, Carloni E, Padalino C, Alimonti A, and Granata M
- Subjects
- Adult, Aged, Aged, 80 and over, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Cohort Studies, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Hyaluronic Acid administration & dosage, Hyaluronic Acid adverse effects, Hyaluronic Acid therapeutic use, Injections, Intra-Articular, Male, Middle Aged, Osteoarthritis, Hip diagnostic imaging, Prospective Studies, Severity of Illness Index, Treatment Outcome, Ultrasonography, Hyaluronic Acid analogs & derivatives, Osteoarthritis, Hip drug therapy
- Abstract
Objective: To evaluate the efficacy and the tolerability of viscosupplementation (VS) with hyaluronic acid (Hylan GF 20) in a cohort of 36 patients affected by hip osteoarthritis through a 18 months follow-up., Methods: Viscosupplementation was performed with an anteriorsagittal approach, under ultrasound guidance. 36 patients were administered hyaluronic acid intraarticularly in the hip, with a unique injection of Hylan G-F20, which could be repeated after at least 3 months. Treatment efficacy was assessed by functional index WOMAC, pain evaluation on a visual analogue scale and NSAID consumption. All such parameters were recorded at the time of the first injection and then 3, 6, 9, 12 and 18 months later., Results: Statistically significant reduction of all parameters was observed three months after the injection, and was still maintained at the timepoints 6, 9, 12 and 18 months. No local side effects have been observed, nor systemic complications., Conclusions: Our data show that viscosupplementation is a promising approach for hip osteoarthritis, providing beneficial effects in a long-term follow up. Yet, the topic deserves further and wider studies, so to define the number of injections to administer and suggest a fit interval between subsequent injections.
- Published
- 2006
4. [Intra-articular treatment with Hylan G-F 20 under ultrasound guidance in hip osteoarthritis. Clinical results after 12 months follow-up].
- Author
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Migliore A, Tormenta S, Valente C, Massafra U, Martin Martin LS, Carmenini E, Bernardini A, and Alimonti A
- Subjects
- Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Hyaluronic Acid administration & dosage, Injections, Intra-Articular, Injections, Intralesional, Male, Middle Aged, Osteoarthritis, Hip diagnostic imaging, Pilot Projects, Prospective Studies, Ultrasonography, Hyaluronic Acid analogs & derivatives, Osteoarthritis, Hip drug therapy
- Abstract
Hip is a site very commonly affected by osteoarthritis (OA), yet few data exist in literature regarding intra-articular use of hyaluronic acid in this pathology. We evaluated the efficacy of Hylan G-F 20 hip viscosupplementation performed under ultrasound guidance. We enrolled 26 patients affected by symptomatic hip OA and treated them with a single intraarticular injection of Hylan G-F 20, which could be repeated every two months. The injection was performed under ultrasound guidance with an antero-superior approach. Treatment efficacy was assessed through Lequesne index, visual analogue scale (VAS) pain quantification, and NSAID intake at the timepoint zero (baseline), and after 2, 6 and 12 months. We observed a statistically significant reduction of all considered parameters at the timepoints 2 and 6 months, when compared to baseline. At 12 months the changes were still statistically significant for all parameters for about 50% of the patients. No side effect was observed, nor systemic complication. Viscosupplementation is a promising approach for hip OA, although further and wider studies are wanted to determine how long the beneficial effect lasts, and what is the optimal number of injections to administer.
- Published
- 2005
- Full Text
- View/download PDF
5. [Safety profile of 185 ultrasound-guided intra-articular injections for treatment of rheumatic diseases of the hip].
- Author
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Migliore A, Tormenta S, Martin Martin LS, Valente C, Massafra U, Latini A, and Alimonti A
- Subjects
- Adrenal Cortex Hormones administration & dosage, Aged, Anesthetics, Local administration & dosage, Female, Humans, Hyaluronic Acid administration & dosage, Male, Safety, Software, Time Factors, Hip Joint, Injections, Intra-Articular, Rheumatic Diseases drug therapy, Ultrasonography
- Abstract
Objective: We have developed a standardized technique for intra-articular injection of the hip joint with the purpose of extending routine intra-articular injection of hyaluronans and steroids to the hip, as commonly used in the knee. The purpose of this study was to examine the safety of this technique in an extended series of patients., Methods: A 7 MHz linear or 3.5 MHz convex transducer was used with a sterilized biopsy guide attached. Intra-articular (IA) injection was performed by inserting into the biopsy guide a 20 gauge needle with the anterosuperior approach. Then, using biopsy real-time guidance software, the needle was advanced into the anterior capsular recess, at the level of the femoral head., Results: The standardised technique was used to inject 97 patients (114 hips) with 185 injections of either steroid/local anaesthetic (10) or hyaluronan (175) over a three-year period. The treatment was well tolerated with few, and exclusively local, side effects. No systemic side effects or joint infections were observed in our study. The colour Doppler vision allowed us to avoid injecting blood vessels. In all cases direct visualization of needle introduction and progression into the articular space was shown by on-screen guidance. Ultrasound guidance is more economic and faster in comparison to the TC or fluoroscopic guidance. Contrary to TC or fluoroscopic techniques ultrasound does not require use of radiations or iodized contrast., Conclusion: Our data suggest that the administration of hyaluronans or steroids with ultrasound-guided intra-articular injection is a safe technique for treatment of rheumatic diseases of the hip.
- Published
- 2004
- Full Text
- View/download PDF
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