51 results on '"Virgilio, V."'
Search Results
2. Research designs starting from effects.
- Author
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Lima-Gómez V
- Subjects
- Humans, Research Design
- Published
- 2023
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3. More graphs in the papers of Cirugía y Cirujanos?
- Author
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Lima-Gómez V
- Subjects
- Humans, Retrospective Studies, Colectomy, Rectal Neoplasms surgery
- Published
- 2022
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4. Incidence and onset time of epiretinal membranes after two retinopexy techniques.
- Author
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Quiroz-Reyes MA, Quiroz-González MA, Montaño M, and Lima-Gómez V
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- Humans, Incidence, Retrospective Studies, Scleral Buckling adverse effects, Scleral Buckling methods, Treatment Outcome, Vitrectomy adverse effects, Vitrectomy methods, Epiretinal Membrane diagnosis, Epiretinal Membrane epidemiology, Epiretinal Membrane surgery, Retinal Detachment epidemiology, Retinal Detachment etiology, Retinal Detachment surgery
- Abstract
Objective: To compare the incidence and onset time of epiretinal membranes after two surgical techniques to treat retinal detachment (retinopexy)., Method: Non-experimental, retrospective, longitudinal and comparative study in patients treated of primary rhegmatogenous retinal detachment either with cryotherapy and scleral buckle (group 1) or vitrectomy techniques (group 2), without an epiretinal membrane at the moment of surgery. We compared the incidence of postoperative epiretinal membrane between groups, the median onset time (Mann-Whitney's U) and the proportions of eyes without an epiretinal membrane along time with a survival analysis (log-rank)., Results: 112 eyes in group 1, 48 in group 2; the incidence of epiretinal membrane was 23.2% in group 1 and 20.8% in group 2 (p = 0.8). The median time of onset was 12 weeks in group 1 (interquartile rank 8.75-16) and 18 in group 2 (12.5-22, p = 0.02). The log-rank test showed no differences of incidence along the follow-up between groups (p = 0.6)., Conclusions: Epiretinal membranes appear early after retinopexy, before in eyes treated with crio-retinopexy. Although their incidence does not differ between groups, detecting them could start two months after a scleral buckle and three after a vitrectomy procedure., (Copyright: © 2022 Permanyer.)
- Published
- 2022
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5. CLINICAL DECISION MAKING IN OLDER ADULTS WITH COVID-19 IN DEVELOPING COUNTRIES: LOOKING BEYOND CHRONOLOGICAL AGE.
- Author
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Gómez-Moreno C, Hernández-Ruiz V, Hernández-Gilsoul T, and Avila-Funes JA
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- Activities of Daily Living, Aged, Aged, 80 and over, COVID-19, Female, Frail Elderly, Geriatric Assessment methods, Humans, Male, Patient Preference, Prognosis, Resource Allocation ethics, SARS-CoV-2, Triage, Vulnerable Populations, Betacoronavirus, Clinical Decision-Making, Coronavirus Infections economics, Coronavirus Infections epidemiology, Developing Countries economics, Emergency Service, Hospital economics, Pandemics economics, Pneumonia, Viral economics, Pneumonia, Viral epidemiology, Resource Allocation standards
- Abstract
Background: The coronavirus disease 2019 (COVID-19) has been declared a global pandemic. Older adults have been found as a vulnerable group for developing severe forms of disease and increased mortality., Objective: The objective of the study was to propose a pathway to assist the decision-making process for hospital resource allocation for older adults with COVID-19 using simple geriatric assessment-based tools., Methods: We reviewed the available literature at this point of the COVID-19 outbreak, focusing in older adult care to extract key recommendations for those health-care professionals who will be treating older adults in the hospital emergency ward (HEW) in developing countries during the COVID-19 pandemic., Results: We listed a series of easy recommendations for non-geriatrician doctors in the HEW and suggested simple tools for hospital resource allocation during critical care evaluation of older adults with COVID-19 in low- and middle-income countries., Conclusions: Age must not be used as the sole criterion for resource allocation among older adults with COVID-19. Simple and efficient tools are available to identify components of the comprehensive geriatric assessment, which could be useful to predict outcomes and provide high-quality care that would fit the particular needs of older adults in resource-limited settings amidst this global pandemic., (Copyright: © 2020 Permanyer.)
- Published
- 2020
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6. Sequential closure of the abdominal wall for the management of open abdomen. A new surgical technique.
- Author
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Flores-Álvarez E, De la Torre-González JC, Rivera-Barragán V, and De la Cruz-Álvarez LD
- Subjects
- Abdomen, Adult, Fasciotomy, Female, Humans, Laparotomy, Male, Abdominal Injuries surgery, Abdominal Wall surgery, Intra-Abdominal Hypertension etiology, Intra-Abdominal Hypertension surgery
- Abstract
Background: The open abdomen is a surgical technique used in the treatment of patients with abdominal sepsis, abdominal trauma and abdominal hypertension syndrome., Objective: The aim was to demonstrate the effectiveness of a new surgical technique designed for the management and closure of the abdominal wall in patients with open abdomen., Method: Study of all patients treated with open abdomen in our Hospital over a five-year period., Results: It were included 24 patients, 18 men and 6 women. The average age was 41.5 ± 15.9 years. Operative diagnosis was abdominal compartment syndrome in 7 (29%) cases, abdominal sepsis in 9 (38%), and abdominal trauma in 8 (33%). The median of APACHE II score was 8 points (range: 5-21) while the assessment of SIRS score had a median of 2 points (range: 1-4). The median of surgical procedures performed in operating room was two per patient. The median of fascial surgical closures performed in the patient bed was four. A successful closure of the abdominal wall was performed in 21 of 22 live patients (95%)., Conclusions: The sequential closure of the abdominal wall is an effective technique that offers an alternative to the management of the open abdomen., (Copyright: © 2020 Permanyer.)
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- 2020
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7. Circularity of the foveal avascular zone and its correlation with parafoveal vessel density, in subjects with and without diabetes.
- Author
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Somilleda-Ventura SA, Razo-Blanco-Hernández DM, Reyes-Calderón JA, Ceballos-Reyes GM, and Lima-Gómez V
- Subjects
- Adult, Aged, Cross-Sectional Studies, Diabetic Retinopathy complications, Female, Fovea Centralis anatomy & histology, Fundus Oculi, Humans, Male, Middle Aged, Prospective Studies, Statistics, Nonparametric, Tomography, Optical Coherence, Capillaries pathology, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy pathology, Fovea Centralis pathology, Macula Lutea blood supply
- Abstract
Purpose: To characterize the distribution of the foveal avascular zone circularity and its correlation with parafoveal vessel density, in subjects with and without diabetes., Methods: Observational, descriptive, cross-sectional, and prospective study; subjects without diabetes (Group 1), with diabetes without retinopathy (Group 2), or with diabetic retinopathy (Group 3) were included. Means of foveal avascular zone circularity and parafoveal vessel density were compared between groups (Kruskal-Wallis) and their correlation was calculated with Spearman's Rho test., Results: Seventy-seven eyes; central vessel density mean was higher in Group 1 than in Group 2 and higher in Group 2 than in Group 3; inner and complete vessel density means were also higher in Group 2 than in Group 3. The mean of the foveal avascular zone circularity did not differ between groups, and in Group 3 it had a positive correlation with central (0.45), inner (0.56), and complete (0.53) vessel densities., Conclusions: Circularity does not differ between subjects with diabetes, with and without retinopathy, and has only a low correlation with parafoveal vessel density in people with diabetic retinopathy, which does not allow anticipating a reduction of vessel density in this disease., (Copyright: © 2019 Permanyer.)
- Published
- 2019
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8. Low recurrence of diabetic macular edema, 6 months after focal photocoagulation.
- Author
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Lima-Gómez V and Somilleda-Ventura SA
- Subjects
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Macular Edema epidemiology, Male, Middle Aged, Prospective Studies, Recurrence, Time Factors, Diabetic Retinopathy surgery, Light Coagulation methods, Macular Edema surgery
- Abstract
Objective: To identify the proportion of eyes with recurrence of diabetic macular edema, six months after focal photocoagulation., Method: Non-experimental, analytical, cross-sectional and prospective study in patients with diabetic macular edema treated with focal photocoagulation. The proportion and 95% confidence intervals (95% CI) of eyes with recurrence of edema were identified; the distribution of anatomical variables and visual acuity was compared between eyes with and without recurrence, using Mann-Whitney's U., Results: 145 eyes were evaluated, and only 10 (95%CI: 2.8-11) had a recurrence. Center point thickness and center field thickness means were higher in eyes with recurrence than in eyes without it, but the difference of change mean betwwen groups was not statistically significant., Conclusion: The proportion of recurrent diabetic macular edema recurrence six months after successful focal photocoagulation was lower than the one reported for other treatments of diabetic macular edema, and by recent studies that used photocoagulation., (Copyright: © 2019 Permanyer.)
- Published
- 2019
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9. Reduction of foveal sensitivity in diabetic macular edema with visual acuity 20/20.
- Author
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Lima-Gómez V, García-Rubio YZ, Somilleda-Ventura SA, and Razo-Blanco-Hernández DM
- Subjects
- Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy complications, Female, Humans, Macular Edema etiology, Male, Middle Aged, Prognosis, Prospective Studies, Statistics, Nonparametric, Tomography, Optical Coherence, Visual Acuity, Visual Field Tests, Diabetes Mellitus, Type 2 physiopathology, Diabetic Retinopathy physiopathology, Fovea Centralis physiopathology, Macular Edema physiopathology
- Abstract
Objective: To compare foveal sensitivity in eyes with and without diabetic macular edema, with 20/20 visual acuity., Methods: Non-experimental, comparative, prospective, cross sectional study in eyes with and without retinopathy and focal macular edema, with 20/20 visual acuity. The sample was divided in 3 groups: (1) non-diabetic subjects, (2) diabetics without retinopathy, and 3) diabetics with non-proliferative retinopathy and clinically significant macular edema. Median foveal sensitivity was compared between groups (Kruskal Wallis test)., Results: 86 eyes (28 in group 1, 26 in group 2 and 32 in group (3). Medians shown a statistical difference between groups (p = 0.001). Median foveal sensitivity was significantly lower in group 3 than in group 1 (p = 0.001) and than in group 2 (p = 0.03). Median foveal sensitivity did not differ between groups 1 and 2 (p = 0.10)., Conclusion: Foveal sensitivity in diabetic macular edema and visual acuity 20/20 is lower in eyes with center sparing clinically significant macular edema and 20/20 visual acuity. The prognostic value of this dysfunction requires evaluation, in order to learn whether early treatment is required in these eyes., (Copyright: © 2019 Permanyer.)
- Published
- 2019
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10. [Sensibilidad foveal en ojos con edema macular diabético con y sin engrosamiento temporal perifoveal].
- Author
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Lima-Gómez V, García-Rubio YZ, Somilleda-Ventura SA, and Razo-Blanco-Hernández DM
- Subjects
- Adult, Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy complications, Female, Fovea Centralis pathology, Humans, Macular Edema complications, Male, Middle Aged, Retrospective Studies, Diabetic Retinopathy physiopathology, Fovea Centralis physiopathology, Macular Edema physiopathology, Visual Acuity
- Abstract
Background: Visual improvement after photocoagulation in focal diabetic macular edema is more frequent when temporal perifoveal area is not affected; functional status before treatment could be worse in eyes with perifoveal temporal thickening. The correlation between visual acuity and foveal sensitivity (usually significant), would allow to compare macular function., Objective: To compare the correlation between retinal sensitivity and visual acuity in eyes with diabetic macular edema, with and without temporal perifoveal thickening., Method: Non-experimental, retrospective, comparative, cross-sectional study in type 2 diabetics with macular edema. The correlation between foveal sensitivity and visual acuity was compared in eyes without temporal perifoveal thickening (group 1) and eyes with it (group 2). Multiple regression analysis was used to identify the contribution of foveal sensitivity to the changes of visual acuity; other variables were: center point thickness, center field thickness, temporal perifoveal thickness and macular volume., Results: 60 eyes in group 1, 29 eyes in group 2. Mean sensitivity did no differ between groups (30.0 ± 0.59 vs. 28.4 ± 1.05 dB; p = 0.2), but the correlation between sensitivity and visual acuity did it (group 1, rho: -0.41; group 2, rho: -0.25). In group 1, foveal sensitivity was the only explaining variable of the regression model (beta: -0.52), in group 2 no one explaining variable was included and temporal perifoveal thickness had a negative correlation with foveal sensitivity (rho: -0.60)., Conclusions: Temporal perifoveal thickening reduces the correlation between foveal sensitivity and visual acuity in eyes with diabetic macular edema., (Copyright: © 2019 Permanyer.)
- Published
- 2019
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11. Steam roller maneuver in pneumatic retinopexy. Does it work?
- Author
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Pérez-Aragón BJ, Pérez-Montaño CR, Ramírez-Estudillo JA, Robles-Contreras A, and Lima-Gómez V
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Injections, Intraocular, Male, Middle Aged, Prospective Studies, Retinal Detachment etiology, Retinal Perforations complications, Sulfur Hexafluoride administration & dosage, Treatment Outcome, Visual Acuity, Head Movements, Physical Therapy Modalities, Retinal Detachment surgery
- Abstract
Objective: To identify the efficacy and safety of the steam-roller maneuver, in patients treated with pneumatic retinopexy., Method: Experimental, prospective, comparative, longitudinal study in patients with retinal detachment, treated with pneumatic retinopexy. Patients were assigned to one of two groups: without steam roller maneuver (group 1) or with it (group 2). The proportions of single-intervention anatomical success, visual improvement, anatomical success with reintervention, and adverse events were compared between groups (chi squared); preoperative and postoperative visual acuity in logMAR was compared within groups (Wilcoxon's t)., Results: 40 eyes were evaluated (mean age 55.9 ± 13.3 years); 15 were assigned to group 1, 25 to group 2. The proportions of single-intervention anatomical success, visual improvement, anatomical success with reintervention, and adverse events did not differ between groups (p > 0.05). At the end of follow up, visual acuity improved in both groups; however, it only improved in group 2, in eyes with single intervention anatomical success (mean log MAR before surgery 1.72 ± 1.64; after surgery 0.61 ± 0.61; p = 0.008)., Conclusions: The steam roller maneuver is efficient for improving visual acuity in patients with pneumatic retinopexy, who achieve single intervention anatomical success; furthermore, the maneuver does not impair prognosis in eyes that require reintervention., (Copyright: © 2019 Permanyer.)
- Published
- 2019
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12. Comparison of anatomic and functional success of treatment for retinal detachment with macular involvement between two retinopexy techniques.
- Author
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Brito-Sandoval P, Espinosa-Soto IC, Ramírez-Estudillo JA, and Lima-Gómez V
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- Adolescent, Adult, Aged, Aged, 80 and over, Chi-Square Distribution, Child, Confidence Intervals, Female, Humans, Macula Lutea, Male, Middle Aged, Retinal Detachment etiology, Retrospective Studies, Treatment Outcome, Visual Acuity, Young Adult, Retinal Detachment surgery, Vitrectomy methods, Vitreoretinal Surgery methods
- Abstract
Objective: To compare the frequency of anatomic and functional success, between eyes with uncomplicated rhegmatogenous retinal detachment treated with exoplant or vitrectomy., Method: Non-experimental, retrospective, comparative and longitudinal study in patients with rhegmatogenous retinal detachment, <20/200 visual acuity and macular involvement, treated with exoplant (group 1) or vitrectomy (group 2), and 9 months follow up, without proliferative vitreoretinopathy or other vitreoretinal disease that reduced vision. The frequencies of anatomic success (attached retina) and functional success (visual acuity > 20/200) were compared between groups at the end of follow up (chi squared and odds ratio)., Results: 114 patients, mean age 48.5 ± 16.6 years, mean detachment duration 49.8 ± 32.0 days; group 1 had 33 subjects (28.9%) and group 2 had 81 (71.1%). Anatomic success was achieved in 27 subjects of group 1 (81.8%; 95% confidence interval [95% CI]: 68.7-95) and in 74 of group 2 (91.4%; 95% CI: 85.2-97.5; p = 0.1); 14 subjects of group 1 (42.4%) and 21 of group 2 (25.9) had functional success (p = 0.1)., Discussion: In our media, the frequencies of anatomic and functional success after treating rhegmatogenous retinal detachment did not differ between exoplant and vitrectomy. Early detection should be favored, to increase the frequency of postoperative visual improvement., (Copyright: © 2019 Permanyer.)
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- 2019
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13. [Expected effect of retinal thickness after focal photocoagulation in diabetic macular oedema].
- Author
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Garcia-Rubio YZ, Razo Blanco-Hernández DM, and Lima-Gómez V
- Subjects
- Blood Glucose, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy pathology, Female, Fovea Centralis pathology, Humans, Macular Edema etiology, Macular Edema pathology, Male, Middle Aged, Organ Size, Retrospective Studies, Visual Acuity, Diabetic Retinopathy surgery, Laser Coagulation, Macular Edema surgery, Retina pathology
- Abstract
Background: Macular oedema is a form of diabetic retinopathy that can be treated with photocoagulation. The expected effect of treatment varies, and may depend on the previous characteristics of retinal thickening., Objective: To determine whether the change in retinal thickness after focal photocoagulation for diabetic macular oedema varies due to the presence of anatomical features that may justify a separate assessment., Material and Methods: Non-experimental, comparative, retrospective, longitudinal study. The mean percentage change in macular volume was compared in eyes with diabetic macular oedema, 3 weeks after focal photocoagulation. The analysis was stratified according to the presence of central and perifoveal temporal thickening (Mann-Whitney U). A regression analysis was performed to identify the contribution of the anatomical variables before photocoagulation to the change in macular volume., Results: A total of 72 eyes were evaluated. The mean change of macular volume in the sample was -0.68±3.84%. In the multiple regression analysis, the changes of perifoveal temporal (beta 0.54, p<0.001) and central field thickness (beta 0.3, p =0.01) contributed to the change of macular volume (R=0.64). Macular volume decreased by a mean of -2.1±4.3% in eyes with temporal perifoveal thickening, and increased by 0.5±2.8% (p =0.007) in eyes with no thickening., Conclusion: Perifoveal temporal thickening before photocoagulation changes the expected effect of this therapy on macular volume in eyes with focal diabetic macular oedema. It is recommended to evaluate the effect separately, and according to the perifoveal temporal thickness., (Copyright © 2015 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.)
- Published
- 2016
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14. [Association between visual improvement after photocoagulation and the use of angiotensin converting enzyme inhibitors in diabetic macular oedema].
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Somilleda-Ventura SA, García-Rubio YZ, Razo Blanco-Hernández DM, and Lima-Gómez V
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- Adult, Aged, Aged, 80 and over, Angiotensin-Converting Enzyme Inhibitors pharmacology, Antihypertensive Agents pharmacology, Combined Modality Therapy, Diabetic Retinopathy complications, Female, Humans, Hypertension complications, Hypertension drug therapy, Macular Edema complications, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Visual Acuity, Angiotensin-Converting Enzyme Inhibitors therapeutic use, Antihypertensive Agents therapeutic use, Diabetic Retinopathy surgery, Laser Coagulation, Macular Edema surgery
- Abstract
Background: Angiotensin converting enzyme inhibitors are effective in delaying the progression of diabetic retinopathy. It is unknown if their use is associated with a better visual outcome in patients with diabetic macular oedema., Material and Methods: A non-experimental, comparative, longitudinal and retrospective study was performed on patients with diabetic macular oedema treated by focal photocoagulation, and with systemic arterial hypertension treated with angiotensin converting enzyme inhibitors (Group 1), and without hypertension (Group 2). The dependent variable was the proportion with visual improvement, operatively defined as the gain of one or more lines of vision three weeks after photocoagulation. The independent variable was the use of angiotensin converting enzyme inhibitors. The proportion of eyes with visual improvement after treatment was compared between groups using the Chi squared (χ(2)) test., Results: A total of 33 eyes (51.6%) were assigned to group 1, and 31 (48.2%), to group 2. The mean of visual acuity improved after three weeks, compared with baseline (p=0.002). The proportion of eyes with visual improvement did not differ between patients treated with angiotensin converting enzyme inhibitors (45.5%) and those that did not use them (51.6%, p=0.4)., Conclusions: There was no statistical difference in the proportion of eyes with visual improvement between patients treated with angiotensin converting enzyme inhibitors and in those where they were not used. There is no support for the inhibition of angiotensin II in addition to photocoagulation for improving the outcome in patients with diabetic macular oedema., (Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.)
- Published
- 2016
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15. [Lack of correlation between retinal variables before treatment and poor functional response after focal photocoagulation in diabetic macular oedema].
- Author
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Ávila-Alcaraz Y, Razo Blanco-Hernández DM, García-Rubio YZ, and Lima-Gómez V
- Subjects
- Adult, Aged, Aged, 80 and over, Confidence Intervals, Diabetic Retinopathy diagnostic imaging, Female, Fluorescein Angiography, Humans, Hypertension complications, Macular Edema diagnostic imaging, Male, Middle Aged, Retina diagnostic imaging, Retrospective Studies, Tomography, Optical Coherence, Treatment Outcome, Visual Acuity, Diabetic Retinopathy surgery, Light Coagulation, Macular Edema surgery, Retina pathology
- Abstract
Background: Although photocoagulation reduces the incidence of moderate visual loss in eyes with focal diabetic macular oedema, some eyes may lose some vision after treatment. The proportion of eyes with poor functional response after photocoagulation, and whether any retinal variable is associated with this, is unknown., Objective: To determine the proportion of eyes with diabetic macular oedema that have a poor functional response after focal photocoagulation, and their associated features., Material and Methods: A non-experimental, longitudinal, comparative and retrospective study was conducted. The proportion and 95% confidence intervals (CI) of diabetics with macular oedema that had a poor functional response after focal photocoagulation (any visual loss after 6 weeks) were identified. The means of retinal variables before treatment were compared between eyes with and without a poor functional response using the Student t test for independent means., Results: The study included 115 eyes of patients aged 59.3 (SD 9.24) years. Visual acuity was greater than or equal to 0.5 in 63 eyes (54.8%). A total of 33 eyes had a poor functional response after photocoagulation (28.7%, 95% CI: 13.3 to 44.1). The comparison between retinal variables and visual acuity before treatment did not show any differences between eyes with or without a poor functional response and eyes., Conclusion: Retinal thickening and visual acuity improved or did not change in 71.3% of eyes with diabetic macular oedema with a single photocoagulation procedure. Retinal variables that are usually evaluated were unable to identify the remaining 28.7%, which could lose vision after that treatment, and would require additional interventions., (Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.)
- Published
- 2016
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16. [Features associated with retinal thickness extension in diabetic macular oedema].
- Author
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Razo Blanco-Hernández DM, Lima-Gómez V, and García-Rubio YZ
- Subjects
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Diabetic Retinopathy pathology, Macular Edema pathology, Retina pathology
- Abstract
Background: Clinically significant macular edema has features that are associated with a major risk of visual loss, with thickening that involves the centre of the macula, field 7 or visual deficiency, although it is unknown if these features are related to retinal thickness extension., Material and Methods: An observational, analytical, prospective, cross-sectional and open study was conducted. The sample was divided into initial visual acuity ≥0.5, central field thickness, center point thickness, field 7 and macular volume more than the reported 2 standard deviation mean value in eyes without retinopathy. The extension was determined by the number of the central field area equivalent thickening and these features were compared with by Student's t test for independent samples., Results: A total of 199 eyes were included. In eyes with visual acuity of ≥0.5, the mean extension was 2.88±1.68 and 3.2±1.63 in area equivalent in eyes with visual acuity <0.5 (p=0.12). The mean extension in eyes with less than 2 standard deviation of central field thickness, center point thickness, field 7 and macular volume was significantly lower than in eyes with more than 2 standard deviations (1.9±0.93 vs. 4.07±1.49, 2.44±1.47 vs. 3.94±1.52, 1.79±1.07 vs. 3.61±1.57 and 1.6±0.9 vs. 3.9±1.4, respectively, p<0.001)., Conclusions: The extension of retinal thickness is related with the anatomical features reported with a greater risk of visual loss, but is not related to initial visual deficiency., (Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.)
- Published
- 2015
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17. Retinal thickness after focal photocoagulation for diabetic macular edema with and without temporal perifoveal thickening.
- Author
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Lima Gómez V, Razo Blanco-Hernández DM, García Rubio YZ, and Sánchez Montoya PA
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Humans, Longitudinal Studies, Macular Edema etiology, Male, Middle Aged, Retrospective Studies, Tomography, Optical Coherence, Treatment Outcome, Visual Acuity, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy surgery, Light Coagulation methods, Macular Edema surgery
- Abstract
Background: Visual improvement after focal photocoagulation in diabetic macular edema is more common in eyes without temporal perifoveal thickening. This feature is related to a lower macular volume before treatment; the higher proportion of visual improvement could be associated with a shorter need of volume reduction., Objective: To compare macular volume before and after focal photocoagulation in eyes with diabetic macular edema, with and without temporal perifoveal thickening., Methods: Non-experimental, retrospective, longitudinal, comparative study in diabetics with macular edema treated with focal photocoagulation. Macular volume measured with optical coherence tomography, and best corrected visual acuity were compared between eyes with (group 1) and without temporal perifoveal thickening (group 2, independent samples Student's t test). The comparison was also performed after stratifying the groups by baseline visual acuity., Results: One hundred and twenty eyes, 65 eyes from group 1 (54.2%) and 55 from group 2 (45.8%). Mean volume before and after treatment and mean absolute and percentage changes were lower in group 2 (p < 0.001) regardless of visual acuity. Macular volume decreased significantly in eyes of group 1; only eyes in group 2 with visual acuity < 0.5 before treatment increased their visual function (p < 0.001)., Conclusions: Eyes without temporal perifoveal thickening had visual improvement, although their volume did not change statistically. The significant volume reduction in eyes with temporal perifoveal thickening was not associated to visual improvement. The anatomical change was not enough to explain the functional improvement.
- Published
- 2015
18. [Efficacy of dorzolamide in reducing retinal thickness after photocoagulation in diabetic macular oedema].
- Author
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Lima-Gómez V, Bermúdez-Zapata DA, and Blanco-Hernández DM
- Subjects
- Adult, Aged, Anthropometry, Aqueous Humor metabolism, Biological Transport, Carbonic Anhydrase Inhibitors pharmacology, Combined Modality Therapy, Diabetic Retinopathy pathology, Double-Blind Method, Female, Humans, Inflammation, Intraocular Pressure, Macular Edema drug therapy, Macular Edema metabolism, Macular Edema pathology, Male, Microcirculation, Middle Aged, Polyvinyl Alcohol therapeutic use, Retina pathology, Retinal Pigment Epithelium drug effects, Retinal Pigment Epithelium physiopathology, Retinal Vessels metabolism, Sulfonamides pharmacology, Thiophenes pharmacology, Treatment Outcome, Visual Acuity, Carbonic Anhydrase Inhibitors therapeutic use, Diabetic Retinopathy surgery, Light Coagulation adverse effects, Macular Edema surgery, Postoperative Care methods, Retina drug effects, Sulfonamides therapeutic use, Thiophenes therapeutic use
- Abstract
Background: Focal photocoagulation interrupts vascular leakage in diabetic macular edema, and allows the retinal pigment epithelium to withdraw fluid that thickens the retina; this mechanism could be enhanced by dorzolamida, a topical carbonic anhydrase inhibitor., Objective: To determine the efficacy of dorzolamida compared against placebo, in reducing retinal thickness after focal photocoagulation, in eyes with diabetic macular oedema., Material and Methods: Experimental, comparative, prospective, longitudinal, double blind study in diabetics with focal macular oedema treated with photocoagulation. Treated eyes were randomly assigned three weeks after the procedure to receive dorzolamide (group 1) or placebo (group 2), three times daily during three weeks. Means of visual acuity, center point thickness and macular volume were compared 3 and 6 weeks after photocoagulation within groups (Wilcoxon's t) and between groups (Mann-Whitneys's U)., Results: Sixty-nine eyes form patients aged 58.3 ± 8.3 years; 37 were assigned to group 1 and 42 to group 2. Mean center point thickness changed from 178.4 ± 34μm to 170 ± 29.1μm in group 1 (p = 0.04), and from 179.2 ± 22.4μm to 178.6 ± 20.8μm in group 2 (p = 0.7); mean macular volume changed from 7.63 ± 0.52mm(3) to 7.50 ± 0.50mm(3) in group 1 (p = 0.02) and from 7.82 ± 0.43mm(3) to 7.76 ± 0.42mm(3) in group 2 (p = 0.014)., Conclusions: The efficacy of dorzolamide was higher than that of placebo, to reduce retinal thickness after focal photocoagulation in diabetics with macular oedema., (Copyright © 2015. Published by Masson Doyma México S.A.)
- Published
- 2015
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19. [Efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema].
- Author
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Razo Blanco-Hernández DM, Lima-Gómez V, and Asbun-Bojalil J
- Subjects
- Administration, Ophthalmic, Adult, Aged, Aged, 80 and over, Anti-Inflammatory Agents, Non-Steroidal administration & dosage, Diabetes Mellitus, Type 2 complications, Dinoprostone antagonists & inhibitors, Dinoprostone biosynthesis, Female, Humans, Ketorolac administration & dosage, Macula Lutea ultrastructure, Male, Middle Aged, Organ Size drug effects, Postoperative Complications drug therapy, Postoperative Complications etiology, Prospective Studies, Retinitis drug therapy, Retinitis etiology, Tomography, Optical Coherence, Treatment Outcome, Visual Acuity drug effects, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Diabetic Retinopathy surgery, Ketorolac therapeutic use, Light Coagulation adverse effects, Macular Edema surgery, Postoperative Complications prevention & control, Retinitis prevention & control
- Abstract
Background: Photocoagulation reduces the incidence of visual loss in diabetic patients with focal macular edema, but it can induce it for Efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema 6 weeks after treatment and produces visual improvement in some cases. Topical ketorolac may reduce the inflammation caused by photocoagulation and improve visual outcome., Purpose: To determine the efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema., Methods: An experimental, comparative, prospective, longitudinal study in diabetic patients with focal macular edema was conducted. Eyes were randomized into two groups of topical treatment for 3 weeks after photocoagulation (A: ketorolac, B: placebo). Best corrected visual acuity before and after treatment was compared in each group (paired t test), and the proportion of eyes with visual improvement was compared between groups (χ(2)). The evaluation was repeated after stratifying for initial visual acuity (≥ 0.5, < 0.5)., Results: There were 105 eyes included. In group A (n= 46) mean visual acuity changed from 0.50 to 0.58 (p= 0.003), and from 0.55 to 0.55 in group B (n= 59, p= 0.83); mean percent change was 22.3% in group A and 3.5% in group B (p= 0.03). Visual improvement was identified in 25 eyes from group A (54.3%) and 19 from group B (32.2%, p= 0.019, RR 1.65); the difference only persisted when initial visual acuity was ≥ 0.5 (10 [40%], group A, 5 [14.7%], group B, p= 0.02, RR 2.72)., Conclusion: Topical ketorolac was more effective than placebo to improve best corrected visual acuity in diabetic patients with focal macular edema.
- Published
- 2014
20. [Bilateral spontaneously reattached rhegmatogenous retinal detachment. Case report and differential diagnosis with pigmentary retinopathies].
- Author
-
García-Guzmán JG, Franco-Yáñez Y, and Lima-Gómez V
- Subjects
- Aged, Cataract complications, Diabetic Retinopathy complications, Diagnosis, Differential, Electroretinography, Female, Fundus Oculi, Gliosis complications, Humans, Hypertension complications, Phacoemulsification, Remission, Spontaneous, Retinal Detachment complications, Retinal Detachment pathology, Retinal Perforations complications, Retinal Perforations pathology, Retinal Pigment Epithelium pathology, Retinitis Pigmentosa diagnosis, Retinal Detachment diagnosis, Retinal Perforations diagnosis
- Abstract
Background: A dark pigmentation of the ocular fundus presents in degenerative diseases such as retinitis pigmentosa; this disease must be distinguished from others whose evolution is not progressive, in order to estimate the functional prognosis of the patient., Objective: To analyze the features which distinguish spontaneously reattached retinal detachment from other causes of ocular fundus pigmentation, in order to be able to identify it even in bilateral cases., Clinical Case: A case of a female with chronic visual loss is presented, who was referred for evaluation with the diagnosis of a pigmented retinopathy. Clinical exploration discarded causes as retinitis pigmentosa, retinal inflammatory diseases or trauma. Based on the clinical features, on the topography of pigmentation and in the information provided by electroretinography, a bilateral spontaneous reattachment of rhegmatogenous retinal detachment was diagnosed made. Clinical features of this entity are discussed, as well as the diagnostic approach to distinguish it from other pigment retinopathies., Conclusion: Clinical features of spontaneously reattached retinal detachment allow the explorer to distinguish it from other causes of bilateral pigmentation, despite presenting bilaterally. Since the prognosis of the attached retina is better than that of a degenerative disease, the correct diagnosis makes rehabilitation easier.
- Published
- 2014
21. [Status of center point thickness and correlation between anatomic and best corrected visual acuity changes after photocoagulation, in diabetic macular edema].
- Author
-
Lima-Gómez V and Razo Blanco-Hernández DM
- Subjects
- Adult, Aged, Blood Glucose analysis, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 drug therapy, Female, Glycated Hemoglobin analysis, Humans, Hypertension complications, Hypoglycemic Agents therapeutic use, Insulin therapeutic use, Macular Edema etiology, Macular Edema pathology, Male, Middle Aged, Prospective Studies, Treatment Outcome, Visual Acuity, Diabetic Retinopathy complications, Light Coagulation, Macula Lutea pathology, Macular Edema surgery
- Abstract
Background: Center point thickness in diabetic macular edema varies after photocoagulation according to its baseline status; it is unknown whether this variation reduces the correlation between anatomic and visual acuity changes., Objective: to identify the contribution of baseline center point thickness to the correlation between anatomic and visual acuity after photocoagulation, in eyes with diabetic macular edema., Methods: non-experimental, prospective, longitudinal, analytical study in diabetics with macular edema treated with photocoagulation, stratified by groups: visual acuity < 0.5 with (group 1) or without central thickening (group 2), and visual acuity = 0.5 with (group 3) or without central thickening (4). The correlations between changes of center point thickness, macular volume, and visual acuity were identified (Spearman)., Results: 79 eyes, 17 in group 1 (21.5%), 21 in group 2 (26.6%), 14 in group 3 (17.7%) and 27 in group 4 (34.2%). Center point thickness increased in groups 2 and 4, visual acuity decreased in group 3 and macular volume in all the groups. The correlations between center point thickness and best corrected visual acuity changes in group 3, and between macular volume and visual acuity in group 1 were negative. The correlations between anatomic variables and visual acuity were low in the sample (r= 0.14)., Conclusion: the increase of center point thickness in eyes without baseline central thickening produced opposite correlations between groups, which reduced the correlations in the samples. Stratification according to baseline center point thickness would make easier to evaluate other variables that modify the functional outcome after photocoagulation.
- Published
- 2013
22. [Impact of follow-up loss over visual deficiency in open-globe ocular trauma].
- Author
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Lima-Gómez V, García-Rubio YZ, and Blanco-Hernández DM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Endophthalmitis epidemiology, Endophthalmitis etiology, Eye Foreign Bodies complications, Eye Foreign Bodies epidemiology, Eye Foreign Bodies surgery, Eye Injuries, Penetrating complications, Eye Injuries, Penetrating surgery, Female, Follow-Up Studies, Humans, Male, Middle Aged, Postoperative Complications epidemiology, Pupil Disorders epidemiology, Pupil Disorders etiology, Recovery of Function, Retinal Detachment epidemiology, Retinal Detachment etiology, Retrospective Studies, Rupture epidemiology, Rupture surgery, Surgical Wound Infection epidemiology, Surgical Wound Infection etiology, Trauma Severity Indices, Treatment Outcome, Vision Disorders epidemiology, Vision Disorders etiology, Visual Acuity, Wound Infection epidemiology, Wound Infection etiology, Young Adult, Eye Injuries, Penetrating epidemiology, Patient Dropouts statistics & numerical data
- Abstract
Introduction: Open-globe ocular trauma causes visual deficiency; calculating the magnitude of the latter often misses the estimation in patients without follow-up., Aim: to identify the modification of the postoperative proportion of visual deficiency in open-globe ocular trauma, which would introduce considering the proportion estimated in patients without follow-up., Methods: Non-interventional, retrospective, longitudinal, analytical study. Visual outcome in eyes with open-globe trauma, with and without follow-up, was calculated using the Ocular Trauma Score. The observed postoperative proportion of visual deficiency was identified in eyes with follow-up; in eyes without follow-up, the postoperative proportion of visual deficiency was estimated using an analysis of scenarios: best (Ocular Trauma Score), mean (that of eyes with follow-up) and worst (last observation/no visual improvement). The estimated proportion of visual deficiency was added to that observed in eyes with follow-up, and the resulting proportion was compared with that expected in the sample, using the Ocular Trauma Score (χ(2))., Results: 104 eyes, 70 without follow-up and 34 without it. In eyes with follow-up the expected proportion of visual deficiency was 58.6%, and the observed one was 71.4% (p = 0.1); the estimated proportion of visual deficiency in eyes without follow-up was 76.5%. The resulting postoperative proportion of visual deficiency in the sample would be 73.1%, which would overcome that expected by the Ocular Trauma Score (59.6%, p = 0.04)., Conclusions: In open-globe ocular trauma, the efficacy of surgery to reduce the proportion of visual deficiency would decrease with regard to the standard expected by the Ocular Trauma Score, if the deficiency estimated in eyes without follow-up were considered.
- Published
- 2013
23. [Efficacy of vitreorretinal surgery to improve best corrected visual acuity in diabetics with retinopathy].
- Author
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Lima-Gómez V, Mijangos-Medina LF, Hernández-Orgaz JJ, and Bermúdez-Zapata DA
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Diabetic Retinopathy ethnology, Ethnicity, Female, Follow-Up Studies, Humans, Lens Implantation, Intraocular statistics & numerical data, Light Coagulation statistics & numerical data, Macular Edema surgery, Male, Mexico epidemiology, Middle Aged, Retinal Detachment surgery, Retrospective Studies, Silicone Oils therapeutic use, Treatment Outcome, Vitreous Hemorrhage surgery, Young Adult, Diabetic Retinopathy surgery, Phacoemulsification statistics & numerical data, Retina surgery, Visual Acuity, Vitrectomy statistics & numerical data
- Abstract
Background: complications of proliferative diabetic retinopathy require surgical treatment. In 2007 Flaxel reported visual improvement after vitreoretinal surgery in 37% of Latino diabetics; in our country it is estimated that a higher proportion of patients improves, but this has not been documented., Aim: to identify the efficacy of vitreoretinal surgery for improving best corrected visual acuity, in diabetic patients treated at a hospital in Mexico City., Methods: an observational, longitudinal, retrospective, descriptive study was conducted in diabetics who underwent vitreoretinal surgery (2007-2010) with one year follow-up. Visual acuity was measured before surgery and one year after, and it was registered when the retinopexy orphacoemulsification was performed, or silicone tamponade wasused. The proportions and 95% confidence intervals (CI) of patients whose visual acuity improved, did not change or worsened, were compared with those reported by Flaxel in Latino patients (χ(2), relative risk [RR])., Results: 63 patients, mean age 58.5 ± 11.6 years, 26 with retinal detachment (41.3%), phacoemulsification was performed in 50 (79.4%), and silicone was used in 27 (42.9%). BCVA worsened in 12 patients (19%), did not change in 5 (8%) and improved in 46 (73%, 95% CI 62-84); the latter proportion exceeded that reported by Flaxel (p = 0.0005, RR 1.97, 95% CI 1.25-3.1)., Discussion: although the difference was not clinically significant, the efficacy of vitreoretinal surgery to improve visual acuity in the sample was consistently higher than that reported by Flaxel in Latinos, and did not vary from other studies. These results do not support an association between an ethnic group and a lower surgical efficacy.
- Published
- 2012
24. [Efficacy of clinical evaluation in diagnosing injury zone in open globe ocular trauma].
- Author
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Lima-Gómez V, Colas-Calvere MG, and Blanco-Hernández DM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Eye Injuries, Penetrating diagnosis, Female, Humans, Likelihood Functions, Limbus Corneae injuries, Male, Middle Aged, Predictive Value of Tests, Reflex, Pupillary, Retina injuries, Sensitivity and Specificity, Visual Acuity, Young Adult, Corneal Injuries, Eye Injuries diagnosis, Physical Examination, Sclera injuries
- Abstract
Background: Risk of retinal damage in open globe eye injuries increases as the zone (location of the wound vertex) is more rearward. The value of clinical exploration to assess this variable is unknown., Objective: To establish the efficacy of clinical exploration as a diagnostic test to identify the injury zone in open globe ocular trauma., Methods: Assessment of patients with open globe ocular trauma, preoperative clinical assessment of injury zone and surgical description of the wound were carried out. The proportion and 95% confidence intervals (CI) of eyes whose zone changed during surgical repair were established, and the efficacy of clinical evaluation to diagnose zone was estimated. Features of eyes with and without zone change were compared using χ(2) test., Results: 89 eyes, mean age 27.1 years. Clinically, the identified zone was I in 36 eyes (40.4%), II in 38 (31.5%) and III in 25 (28.1%); the identified zone during surgery was I in 36 eyes (40.4%), II in 43 (48.3%) and III in 10 (11.2%). Zone changed in 30 eyes (34%, 95% C.I. 24 to 44). Specificity (96%), positive predictive value (93%) and positive likelihood ratio (13.9) were high only for zone II. No feature was associated with zone change., Conclusions: Clinical exploration was not efficient enough to identify injury zone in open globe trauma and has low prognostic value. It is not necessary to define the injury zone at first contact; it is enough identifying properly the agent, visual function and pupil reflexes for an efficient assessment.
- Published
- 2012
25. [Characteristics associated with visual improvement after focal photocoagulation in diabetic macular edema].
- Author
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Lima-Gómez V and Milagros Razo-Blanco Hernández D
- Subjects
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 diet therapy, Diabetes Mellitus, Type 2 drug therapy, Diabetic Retinopathy blood, Diabetic Retinopathy pathology, Diet, Diabetic, Female, Glycated Hemoglobin analysis, Humans, Hypoglycemic Agents therapeutic use, Macular Edema pathology, Male, Middle Aged, Retina ultrastructure, Retrospective Studies, Risk, Tomography, Optical Coherence, Treatment Outcome, Visual Acuity, Diabetic Retinopathy surgery, Laser Coagulation, Macular Edema surgery
- Abstract
Background: Photocoagulation reduces the incidence of moderate visual loss in patients with clinically significant macular edema (CSME). However, the incidence of visual improvement after treatment is low. Diffuse retinal thickening identified with optical coherence tomography (OCT) and visual loss before treatment have been associated with visual improvement., Objective: To identify features associated with visual improvement after focal photocoagulation for CSME., Methods: Observational, analytical, longitudinal, retrospective study. Diabetic patients with CSME treated with focal photocoagulation were evaluated. Study variables were: visual improvement (defined as a gain of one or more lines in a vision chart) and ocular and systemic features before treatment. Clinical and ancillary test variables were compared between eyes with and without visual improvement. Mann-Whitney's U was used to compare quantitative variables; χ(2) was used for qualitative variables., Results: 99 eyes of 72 patients mean age 60.6 years, 59.6% females. 38.4% had visual improvement after treatment. The incidence of visual improvement was higher in eyes with vision < 20/40 before treatment (58.8 vs. 16.7%, p < 0.001, relative risk 3.53). In eyes with vision = 20/40 before treatment, the probability of improving was 12 times higher when field 7 of the OCT map had no thickening (p < 0.001). The remaining variables showed no significant associations., Conclusions: Up to 48% of treated eyes could achieve visual improvement. Consistently with previous reports, the probability increased in eyes with vision < 20/40 before photocoagulation; when vision before treatment was = 20/40, the incidence of visual improvement increased significantly in eyes without thickening in the temporal parafoveal retina.
- Published
- 2012
26. [Can visual outcome be improved in open globe ocular trauma?].
- Author
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Lima-Gómez V, Ponce de León-Ascencio C, and Milagros Razo Blanco-Hernández D
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Male, Middle Aged, Prospective Studies, Recovery of Function, Retrospective Studies, Trauma Severity Indices, Treatment Outcome, Young Adult, Eye Injuries, Penetrating therapy, Visual Acuity
- Abstract
Background: Visual prognosis of injured eyes estimated by the Ocular Trauma Score (OTS) can be used to evaluate the efficacy of open globe treatment. The aim of this study was to identify the OTS features over which interventions could be performed to improve visual outcome in patients with open globe trauma., Methods: We carried out an observational, longitudinal, retrospective-prospective, analytical study. Patients with open globe trauma from a general hospital were evaluated. The initial proportions of visual deficiency (best corrected visual acuity <20/40) and ambulatory vision (best corrected visual acuity >20/200) were identified, and the corresponding expected proportions and 95% confidence intervals (CI) after treatment were estimated using the OTS; both proportions were compared with those obtained in the sample (χ(2)). OTS features associated with a higher proportion of visual improvement were identified., Results: Fifty eyes were studied (mean age 28.6 ± 19 years, 58.4% males). The initial proportion of visual deficiency changed from 92% to 72% (p = 0.009) and that of ambulatory vision changed from 24% to 52% (p = 0.004); the expected proportion of visual deficiency was 58% (95% C.I. 44-72) and that of ambulatory vision was 64% (95% CI 52-77). In eyes with OTS category 3 where neither ruptures nor surgical retinal diseases were initially found, visual improvement was more common but less than expected., Conclusions: Treatment significantly changed the proportions of visual deficiency and ambulatory vision, but its efficacy was the minimal expected. Standardization of anterior segment surgical procedures may improve visual outcome in eyes with open globe trauma with OTS categories 3 to 5.
- Published
- 2012
27. Prevention of intestinal adhesions as a result of intraperitoneal mesh with the addition of hyaluronic acid/carboxymethylcellulose gel. Experimental model in rats.
- Author
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Mayagoitia-González JC, Gudiño-Amezcua LM, Rivera-Barragán V, Mellado-Díaz AV, and Díaz-Chávez EP
- Subjects
- Animals, Disease Models, Animal, Female, Gels, Peritoneum, Rats, Rats, Wistar, Tissue Adhesions prevention & control, Carboxymethylcellulose Sodium therapeutic use, Hyaluronic Acid therapeutic use, Intestinal Diseases prevention & control, Surgical Mesh adverse effects
- Abstract
Background: Intraperitoneal meshes produce adhesions and intestinal fistula. Composite materials with an antiadherent barrier prevent that complication. There are no studies using gel products in intraperitoneal meshes to keep in contact with viscera., Methods: Two groups of 20 rats each were used. Polypropylene mesh was placed intraperitoneally in both groups adding hyaluronic acid/carboxymethylcellulose gel to the mesh in the study group. At 28 days, rats were sacrificed and evaluated using the Diamond adhesions scale., Results: There were 20 rats in the study group and 19 rats in the control group (one postoperative death). Control group all had adhesions: six (32%) >50% of the mesh surface. In the study group one rat (5%) showed no adhesions, and in 14 (70%) <25% of the mesh surface. Severity showed strong and cohesive adhesions in 11 (58%) control group rats and thin, avascular adhesions in 11 (55%) study group rats. For density, in the study group there were two rats (10%) where adhesions were released spontaneously by separating the flap. There was mild to moderate traction in 16 (80%) study group rats and six (32%) control group rats. Adhesiolysis with scissors was used in the study group (5%) and in 13 (68%) control group rats (p <0.05)., Conclusions: Hyaluronic acid/carboxymethylcellulose gel appears to be effective in reducing the percentage of adhesions to segments of intraperitoneal mesh implants.
- Published
- 2012
28. Expected value of foveal thickness in macular edema in Mexican patients with diabetes.
- Author
-
Lima-Gómez V and Razo Blanco-Hernández DM
- Subjects
- Cross-Sectional Studies, Female, Humans, Male, Mexico, Middle Aged, Prospective Studies, Diabetic Retinopathy pathology, Fovea Centralis pathology, Macular Edema pathology
- Abstract
Background: The tomographic cut-off point to detect macular edema uses an international reference of retinal thickness, which is greater than that in our population. We undertook this study to identify the expected value of central subfield mean thickness (CSMT) in Mexican patients with diabetes with clinically significant macular edema (CSME) and the proportion in which using only the tomographic cut-off point for clinical macular edema (>300 μm) could overlook the diagnosis., Methods: We carried out an observational, analytical, crosssectional and prospective study. Eyes of diabetic patients with CSME (January 2006-June 2007) with a fluorescein angiography and optical coherence tomography were included. The sample was divided according to angiographic type: monofocal (group 1), multifocal (group 2), or diffuse (group 3). The mean of CSMT of each group was weighed by the proportion represented by each group to calculate the all-type expected value. The proportion of eyes with CSMT = 300 μm was identified., Results: Ninety-three eyes were included. Mean age was 60.9 years; there were 57 females (61.3%). Forty-one eyes were assigned to group 1 (44.1%, CSMT 210.63 μm), 31 to group 2 (33.3%, CSMT 279.65 μm), and 21 to group 3 (22.6%, CSMT 327.14 μm). The expected value of CSMT was 259.9 μm, 37.75% over the normal reference in the study population and 23% over the American reference. CSMT was <300 μm in 79.6% of the eyes (95% CI 71.4-87.8)., Conclusions: The expected value of CSMT in Mexican patients with diabetes with CSME was within the range internationally regarded as subclinical. Using local references of CSMT is recommended to avoid overlooking the diagnosis of CSME and overestimating its treatment effect.
- Published
- 2012
29. Disparity between foveal thickness and macular volume in diabetic macular edema.
- Author
-
Lima-Gómez V and Blanco-Hernández DM
- Subjects
- Adult, Aged, Diabetic Retinopathy surgery, Female, Humans, Hypertension complications, Light Coagulation, Macular Edema complications, Macular Edema surgery, Male, Middle Aged, Organ Size, Retrospective Studies, Tomography, Optical Coherence, Treatment Outcome, Diabetic Retinopathy pathology, Fovea Centralis ultrastructure, Macula Lutea ultrastructure, Macular Edema pathology
- Abstract
Background: Optical coherence tomography (OCT) quantifies changes of foveal thickness and macular volume after photocoagulation in diabetic macular edema. Macular volume evaluates the whole macula, but it may underestimate changes in foveal thickness induced by photocoagulation. We undertook this study to evaluate the concordance between macular volume and foveal thickness for identifying clinically significant changes of retinal thickness after photocoagulation for diabetic macular edema., Methods: We carried out an observational, retrospective, longitudinal, analytical study. Center point thickness (CPT), central subfield mean thickness (CSMT) and macular volume were measured with OCT before photocoagulation and 3 weeks after in diabetic patients with focal macular edema (January 2006--January 2010). Concordance among variables to detect clinically significant changes (CPT >17%, CSMT >11%, macular volume >3%) was identified using the kappa test., Results: Sixty eight eyes were included; 47 eyes had nonproliferative retinopathy (69.1%). CPT increased significantly in 14.7% of the sample; CSMT in 8.8%, and macular volume in 11.8%. CPT decreased significantly in 4.4%, CSMT in 8.8%, and macular volume in 42.6%. Concordance was regular for CPT and CSMT increased (57%). Concordance was good for CPT and CSMT decreased (64%). Concordance was regular for CSMT and macular volume decreased in eyes with center involvement (43%). The remaining concordances were poor., Discussion: Two independent events happen after focal photocoagulation: involution of the original thickening and increase in CPT. In order to detect both events, evaluation of either foveal thickness alone or macular volume alone is insufficient., Conclusion: Identifying the efficacy and safety of treatments for diabetic macular edema requires simultaneous measurement of CPT and macular volume.
- Published
- 2012
30. Diabetic retinopathy and complexity of retinal surgery in a general hospital.
- Author
-
Mijangos-Medina LF, Hurtado-Noriega BE, and Lima-Gómez V
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Cataract Extraction statistics & numerical data, Child, Child, Preschool, Cross-Sectional Studies, Diabetic Retinopathy diagnosis, Early Diagnosis, Female, Hospitals, General, Humans, Injections, Intraocular statistics & numerical data, Lens Implantation, Intraocular statistics & numerical data, Lens Subluxation surgery, Male, Middle Aged, Retinal Detachment surgery, Retrospective Studies, Vitrectomy statistics & numerical data, Vitreous Hemorrhage surgery, Young Adult, Diabetic Retinopathy surgery, Ophthalmologic Surgical Procedures statistics & numerical data, Retinal Diseases surgery
- Abstract
Background: Usual retinal surgery (vitrectomy or surgery for retinal detachment) may require additional procedures to deal with complex cases, which increase time and resource use and delay access to treatment. We undertook this study to identify the proportion of primary retinal surgeries that required complex procedures and the associated causes., Methods: We carried out an observational, descriptive, cross-sectional, retrospective study. Patients with primary retinal surgery were evaluated (January 2007-December 2010). The proportion and 95% confidence intervals (CI) of preoperative diagnosis and cause of the disease requiring retinal surgery as well as the causes for complex retinal surgery were identified. Complex retinal surgery was defined as that requiring lens extraction, intraocular lens implantation, heavy perfluorocarbon liquids, silicone oil tamponade or intravitreal drugs, in addition to the usual surgical retinal procedure. The proportion of complex retinal surgeries was compared among preoperative diagnoses and among causes (χ(2), odds ratio [OR])., Results: We studied 338 eyes. Mean age of subjects was 53.7 years, and there were 49% females. The most common diagnoses were vitreous hemorrhage (27.2%) and rhegmatogenous retinal detachment (24.6%). The most common cause was diabetes (50.6%); 273 eyes required complex surgery (80.8%, 95% CI: 76.6-85). The proportion did not differ among diagnoses but was higher in diabetic retinopathy (89%, p <0.001, OR 3.04, 95% CI: 1.63-5.7)., Conclusions: Of the total sample, 80.8% of eyes required complex surgical procedures; diabetic retinopathy increased by 3-fold the probability of requiring these complex procedures. Early treatment of diabetic retinopathy may reduce the proportion of complex retinal surgery by 56%.
- Published
- 2012
31. Severity distribution of diabetic macular edema at the time of diagnosis.
- Author
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Lima-Gómez V, Blanco-Hernández DM, Muñoz-Ibarra P, and Hernández-Rojas ML
- Subjects
- Adult, Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy epidemiology, Diabetic Retinopathy pathology, Female, Glycated Hemoglobin analysis, Humans, Hypertension complications, Macular Edema epidemiology, Macular Edema pathology, Male, Mexico epidemiology, Middle Aged, Prospective Studies, Retina pathology, Severity of Illness Index, Tomography, Optical Coherence, Diabetic Retinopathy diagnosis, Macular Edema diagnosis
- Abstract
Background: The International Clinical Diabetic Macular Edema Disease Severity Scale grades retinal thickening according to its distance from the macular center, but its definitions have not been standardized quantitatively. We undertook this study to identify the severity distribution of diabetic macular edema at the time of diagnosis. We used optical coherence tomography (OCT) in a standardized manner and identified the proportion of eyes that required immediate treatment., Methods: We carried out an observational, prospective, cross-sectional, descriptive study. Diabetic patients with a diagnosis of clinically significant macular edema were evaluated. Severity levels according to the International Clinical Scale were operatively defined, guided by the thickening location in a 6-mm OCT fast macular map, as mild (thickening outside the 3-mm circle), moderate (thickening outside the 1-mm circle), and severe (thickening within the 1-mm circle). The proportion and 95% confidence intervals (CI) were identified for each severity level., Results: We studied 118 eyes (mean ± SD: 59.9 ± 8.3 years). Seventy one eyes had nonproliferative retinopathy (60.1%), 94 eyes (79.7%) had focal macular edema, and 24 eyes (20.3%) showed diffuse edema. Edema severity was mild in 27 eyes (22.9%, 95% CI 15.3-30.5), moderate in 23 (19.5%, 95% CI 12.3-26.6) and severe in 68 (57.6% 95% CI 48.7-66.5)., Conclusions: Standardization of the International Clinical Scale using OCT showed that the most common severity level of macular edema was severe; the minimum expected proportion of eyes with high risk of visual loss secondary to severe edema approached 50%. Opportune detection needs reinforcement because more than half of these eyes require immediate treatment.
- Published
- 2011
32. [Effect of photocoagulation on center point thickness in diabetic macular edema].
- Author
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Lima-Gómez V, Razo Blanco-Hernández DM, and Asbun-Bojalil J
- Subjects
- Adult, Aged, Aged, 80 and over, Diabetes Mellitus, Type 2 complications, Diabetic Retinopathy pathology, Female, Humans, Lasers, Semiconductor, Macular Edema complications, Macular Edema pathology, Male, Middle Aged, Organ Size radiation effects, Retrospective Studies, Tomography, Optical Coherence, Treatment Outcome, Vitreoretinopathy, Proliferative complications, Diabetic Retinopathy surgery, Fovea Centralis pathology, Laser Coagulation, Macular Edema surgery
- Abstract
Background: Photocoagulation is the standard treatment for clinically significant macular edema (CSME). This procedure is effective in reducing macular thickening, but it has been reported that initially it does not improve the thickness at the area of best visual function (center point of the fovea). We undertook this study to compare the effect of focal photocoagulation on center point thickness (CPT) and macular volume 3 weeks after treatment in Mexican diabetic patients with CSME, with and without center point involvement., Methods: We carried out an observational, retrospective, longitudinal, analytical, open study. Type 2 diabetic patients undergoing focal photocoagulation for CSME at a general hospital in Mexico City were evaluated. Mean CPT and macular volume were compared before and 3 weeks after photocoagulation (paired t test) in the sample and in eyes with (group 1) and without (group 2) baseline center point involvement. Absolute and percent CPT and macular volume changes were identified., Results: Fifty-nine eyes (mean age 59.6 years) were studied. CPT mean increased from 193 to 197 μm (p = 0.3), statistically in group 2 (168.8 to 178.5 μm, p <0.001). Macular volume mean changed from 7.8 to 7.6 mm(3) (p <0.001). CPT increased 3.9 μm (3%) in the sample, whereas macular volume decreased 0.26 mm(3) (3.1%). Correlation between changes was 0.089., Conclusions: Although macular volume decreased statistically 3 weeks after photocoagulation, CPT did not and increased statistically in eyes without baseline center point involvement, which was unnoticed in the sample effect. These changes should not be overlooked because dealing with them could improve the early results of treatment.
- Published
- 2011
33. Does the probability of developing ocular trauma-related visual deficiency differ between genders?
- Author
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Blanco-Hernández DM, Valencia-Aguirre JD, and Lima-Gómez V
- Subjects
- Adolescent, Adult, Child, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Sex Factors, Eye Injuries complications, Vision Disorders epidemiology, Vision Disorders etiology
- Abstract
Background: Ocular trauma affects males more often than females, but the impact of this condition regarding visual prognosis is unknown. We undertook this study to compare the probability of developing ocular trauma-related visual deficiency between genders, as estimated by the ocular trauma score (OTS)., Methods: We designed an observational, retrospective, comparative, cross-sectional and open-label study. Female patients aged ≥6 years with ocular trauma were included and matched by age and ocular wall status with male patients at a 1:2 male/female ratio. Initial trauma features and the probability of developing visual deficiency (best corrected visual acuity <20/40) 6 months after the injury, as estimated by the OTS, were compared between genders. The proportion and 95% confidence intervals (95% CI) of visual deficiency 6 months after the injury were estimated. Ocular trauma features and the probability of developing visual deficiency were compared between genders (χ(2) and Fisher's exact test); p value <0.05 was considered significant., Results: Included were 399 eyes (133 from females and 266 from males). Mean age of patients was 25.7 ± 14.6 years. Statistical differences existed in the proportion of zone III in closed globe trauma (p = 0.01) and types A (p = 0.04) and type B (p = 0.02) in open globe trauma. The distribution of the OTS categories was similar for both genders (category 5: p = 0.9); the probability of developing visual deficiency was 32.6% (95% CI = 24.6 to 40.5) in females and 33.2% (95% CI = 27.6 to 38.9) in males (p = 0.9)., Conclusions: The probability of developing ocular trauma-related visual deficiency was similar for both genders. The same standard is required.
- Published
- 2011
34. Sources of error in the use of a system for classifying mechanical injuries of the eye.
- Author
-
Razo-Blanco Hernández DM and Lima-Gómez V
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Young Adult, Diagnostic Errors, Eye Injuries classification, Eye Injuries diagnosis
- Abstract
Background: ocular trauma produces psychological, social and occupational effects that can cause significant impairment. Evaluation of ocular trauma has been standardized by a system for classifying mechanical injuries of the eye (SCMIE). Parameters that are most commonly a source of error for the evaluator and that may lead to classification errors have not been identified., Methods: an observational, retrospective, descriptive, cross-sectional and open study was conducted. Files of patients of either gender, aged 6 years or older, with ocular trauma graded with the SCMIE between 1997 and 2009 were re-evaluated by an independent investigator. The rate and 95% confidence intervals (95% CI) of evaluations that resulted in errors during the re-evaluation of ocular trauma were identified in the sample and in general for each parameter. The disparity between the initial evaluation and the re-evaluation (MacNemar) and the concordance between the evaluations (kappa) were analyzed., Results: of 817 evaluations, 294 had at least one grading error (36%, 95% CI 32.7-39.3). The most frequent error source was the parameter type. The disparity was significant in parameters type A, D, grade 2 and zone II. Overall concordance was good., Conclusions: it is necessary to reinforce the learning curve for some parameters of the SCMIE, especially type, in order to improve its evaluation, so that it can become a valid communication tool that favors early referral to the specialist.
- Published
- 2010
35. [Expected effect of treatment on the rate of visual deficiency after ocular trauma].
- Author
-
Lima-Gómez V and Blanco-Hernández DM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Blindness epidemiology, Blindness etiology, Blindness prevention & control, Child, Child, Preschool, Cross-Sectional Studies, Eye Injuries classification, Eye Injuries complications, Female, Follow-Up Studies, Humans, Male, Mexico epidemiology, Middle Aged, Prevalence, Recovery of Function, Trauma Severity Indices, Treatment Outcome, Urban Population, Vision Disorders epidemiology, Vision Disorders etiology, Visual Acuity, Young Adult, Eye Injuries therapy, Vision Disorders prevention & control
- Abstract
Background: Ocular trauma (OT) is a common cause of monocular blindness and visual impairment worldwide. The Ocular Trauma Score (OTS) is a scale that estimates visual function that an injured eye can achieve 6 months after OT. In a sample population, the OTS may be useful to compare the expected functional result with the result of therapeutic interventions in OT. We undertook this study to identify the expected effect of treatment on the rate of visual deficiency 6 months after OT., Methods: The rate of eyes with trauma-related visual deficiency (best corrected visual acuity <20/40) at the time of diagnosis was compared with that estimated 6 months later using the OTS (95% confidence intervals, CI)., Results: We evaluated 742 patients; 46% had visual deficiency initially (95% CI 43-50.2) and 32.1% would demonstrate it 6 months later (95% CI 28.7-35.4, p <0.001, OR 0.54). The rate changed from 29.1 to 18% in closed-globe (CG) trauma and from 84.3 to 63% in open-globe (OG) trauma., Conclusions: Treating OT would reduce the proportion of visual deficiency by 14.5 percentage points (11 in CG, 21.3 in OG trauma). Up to 66% of the injured eyes could reach normal vision. OT prevention requires enhancement because a high rate of eyes would remain disabled despite receiving the best available treatment.
- Published
- 2010
36. Ocular trauma score at the initial evaluation of ocular trauma.
- Author
-
Lima-Gómez V, Blanco-Hernández DM, and Rojas-Dosal JA
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Injury Severity Score, Male, Middle Aged, Prospective Studies, Retrospective Studies, Young Adult, Eye Injuries diagnosis
- Abstract
Background: The system for classifying mechanical injuries of the eye can identify the status of an injured eye at the trauma room, but it has no prognostic value. The ocular trauma score (OTS) estimates the 6-month visual prognosis, but some of its variables require evaluation by an ophthalmologist. We identified the proportion of injured eyes without diseases that required assessment of an ophthalmologist during the initial evaluation in order to determine whether the OTS could be used by non-ophthalmologists at the trauma room., Methods: We evaluated patients with ocular trauma who attended a general hospital in Mexico City between 1995 and 2008 and graded them with the system for classifying mechanical injuries of the eye. The rate of eyes with retinal detachment and endophthalmitis that needed evaluation by an ophthalmologist was identified, and all the eyes were assigned an OTS category. The proportion and 95% confidence intervals (95% CI) of eyes that could be graded using the OTS in a trauma room was determined., Results: We evaluated 742 eyes. Retinal detachment was found in six eyes (0.8%, 95% CI 0.16-1.44) and endophthalmitis in two eyes (0.3%, 95% CI 0-0.69). The proportion of eyes that could be graded using the OTS in a trauma room was 98.9% (95% CI 98.15-99.65)., Conclusions: OTS can be used to estimate the visual prognosis of almost every injured eye during the initial evaluation in a trauma room without the evaluation of an ophthalmologist.
- Published
- 2010
37. Ocular trauma characteristics associated with urgent retinal surgery.
- Author
-
Lima Gómez V and Muñoz Gutiérrez YE
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Retrospective Studies, Young Adult, Emergency Treatment, Eye Injuries surgery, Retina injuries, Retina surgery
- Abstract
Background: The most common features of the system for classifying ocular injuries of the eye in patients who require urgent retinal surgery were identified, and their predictive value was estimated in order to determine whether they are useful in detecting these patients., Methods: Patients with ocular trauma between 1998 and 2007 were retrospectively evaluated and assigned to one of two groups: group 1 (with injuries that required urgent retinal surgery) and group 2 (without those injuries). The rate and 95% confidence intervals (CI) that group 1 accounted for were identified. The rate of the most common features in group 1 was identified and compared with their rate in group 2 using chi(2) and odds ratio. Predictive values of those features for detecting group 1 were calculated., Results: Two hundred thirty eight eyes (mean age: 27.5 years) were included. Ten eyes were assigned to group 1 (4.2%, 95% CI 1.6-6.7) and 228 eyes were assigned to group 2. The most frequent features in group 1 were open globe (90%), type A open globe (50%), type C open globe (30%), grade 4 (70%) and zone III (70%). The positive predictive value was 60% for type C open globe, and <50% for the remaining features., Conclusions: Although some clinical features had a statistical and clinical association with the need for urgent retinal surgery, their predictive value was insufficient because the rate of eyes that required this intervention was low. The results suggest that open globe and visual loss should be used as referral criteria, regardless of the injuries found.
- Published
- 2010
38. Peritoneal tuberculosis. Report of seven cases.
- Author
-
Flores-Alvarez E, Tello-Brand SE, López-López F, and Rivera-Barragán V
- Subjects
- Abdominal Pain etiology, Adult, Antitubercular Agents therapeutic use, Ascites etiology, Biomarkers, CA-125 Antigen blood, Combined Modality Therapy, Elective Surgical Procedures, Female, Humans, Immunocompromised Host, Laparotomy, Lymphoma diagnosis, Male, Mexico epidemiology, Middle Aged, Ovarian Neoplasms diagnosis, Ovariectomy, Peritoneal Neoplasms diagnosis, Peritoneal Neoplasms secondary, Peritonitis, Tuberculous complications, Peritonitis, Tuberculous diagnosis, Peritonitis, Tuberculous drug therapy, Peritonitis, Tuberculous surgery, Young Adult, Diagnostic Errors, Peritonitis, Tuberculous epidemiology
- Abstract
Background: Peritoneal tuberculosis (TB) is a misdiagnosed clinical entity of low frequency. Due to its rarity, it requires a high index of suspicion in clinical practice. Its incidence has been increasing in recent years., Clinical Cases: We present and analyze seven cases of peritoneal TB diagnosed and treated at four hospitals in Aguascalientes, Mexico during a 5-year period. Mean age of the patients was 47.5 +/- 6.5 years. There were six females and one male. Two patients had a history of treated lung TB. The most frequent clinical data were abdominal pain (six patients), ascites (four patients), and abdominal tumor (three patients). Symptom duration prior to surgery was 5.0 +/- 1.7 months. Abdominopelvic CT examinations revealed unilateral ovarian tumor in four patients, bilateral ovarian tumor in two patients, ascites in four patients, and retroperitoneal adenopathy in one patient. All female patients had elevated serum CA-125 levels with a median of 419 U/ml (range: 286-512 U/ml). All patients had a preoperative diagnosis of malignant tumor. All surgical procedures were elective and consisted of laparotomy with biopsy in three patients, laparotomy with salpingo-oophorectomy in two patients, and laparoscopy with biopsy in two patients. Diagnosis of TB was suspected in all cases during surgery. Mean hospital stay was 2 +/- 0.5 days. There was no postoperative morbidity or mortality., Conclusions: Peritoneal TB is uncommon. Diagnoses should be considered in all patients with ascites, adnexal tumors and elevated serum CA-125 levels.
- Published
- 2010
39. [Asymmetrical bilateral optic neuropathy. Case report].
- Author
-
Razo-Blanco-Hernández DM and Lima-Gómez V
- Subjects
- Adult, Humans, Male, Optic Nerve Diseases diagnosis, Optic Nerve Diseases etiology, Optic Nerve Injuries complications
- Abstract
Background: Diagnosis of traumatic optic neuropathy is difficult during primary care as a result of the absence of optic disk changes or coexisting injuries that may be more apparent. Although there are functional signs that suggest its presence, the lack of a comparison parameter may further prevent its detection. A case of bilateral traumatic optic neuropathy is analyzed to emphasize the need for functional evaluation in the injured eye., Clinical Case: A 34-year-old male presented with severe head trauma, loss of consciousness and type III Lefort facial fracture as a result of a vehicular accident. Seventy two hours after the accident, the left eye had only light perception and an afferent pupillary defect. The right eye had visual deficiency not explained by anterior segment injuries. Therapy was aimed at the left eye and, during follow-up, involvement of the right eye was identified very late. The patient's evolution is analyzed, as well as the causes that prevented early detection of traumatic optic neuropathy in the right eye., Conclusions: Functional evaluation must be used to search for traumatic optic neuropathy in every injured eye. The absence of ocular fundus abnormalities does not rule out the disease, especially when visual deficiency exists. Detection of patients with a positive pupil during initial evaluation of trauma is required in order to refer the patient in a timely manner to the ophthalmologist. The specialist should identify atypical cases and therapy should be initiated as early as possible.
- Published
- 2009
40. [Concordance of two retinal mapping techniques to detect diabetic macular edema].
- Author
-
Lima-Gómez V and Ojeda-Cruz P
- Subjects
- Adult, Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Diabetic Retinopathy pathology, Macular Edema pathology, Tomography, Optical Coherence methods
- Abstract
Background: Optical coherence tomography quantifies retinal thickness, localizes diabetic macular edema (DME), and determines whether it implies visual risk. Evaluation is standardized by the macular mapping technique in two versions: 6 mm and 3.45 mm. The latter version measures with greater detail the zone adjacent to the central 1000 microm but does not evaluate the entire macula. Concordance between maps was evaluated in order to define which version better evaluated DME prospectively., Methods: The rate and 95% confidence intervals (95% CI) of eyes with DME, which had thickening adjacent to the central 1000 microm, was identified in fields of the 6-mm map and in the corresponding fields of the 3.45-mm map. The disparity between rates was identified using McNemar test, and concordance between fields was determined using kappa coefficient., Results: The rate of thickening in the studied area ranged from 31.9 to 50% with overlapping 95% CI between corresponding fields. Although significant differences existed (p <0.05), there was good concordance for 3/8 comparisons and very good concordance in five., Conclusions: Information generated by the 6-mm macular mapping was as valid as that generated by the 3.45 mapping to identify thickening adjacent to the central 1000 microm. We recommend using the 6-mm mapping prior to surgery because it has the advantage of completely measuring the macula.
- Published
- 2009
41. [Surgeon's role in diabetic retinopathy].
- Author
-
Lima-Gómez V
- Subjects
- Blindness etiology, Blindness prevention & control, Diabetes Mellitus diagnosis, Diabetic Retinopathy diagnosis, Diabetic Retinopathy epidemiology, Early Diagnosis, Humans, Mexico epidemiology, Diabetic Retinopathy surgery, General Surgery, Ophthalmology, Physician's Role
- Abstract
Diabetic retinopathy (DR) is the most frequent cause of blindness during the patient's economically active years. The probability of developing this disease increases with the number of diabetic patients in our country, as well as their survival. In general, DR progression is predictable, from minimum changes (barely detectable through ophthalmoscopy) to advanced damage that requires surgical treatment. However, in Mexico, its late detection frequently necessitates retinal surgery. Current resources regarding vitreous and retinal surgery have improved anatomic results in the treatment of DR. Among the most important of these are panoramic vision systems, high-speed cutting equipment, small-caliber microsurgical instruments, endophotocoagulation, adjuvants such as heavy liquids, silicon oil and angiogenesis inhibitors, which have been the topic of several recent studies.
- Published
- 2008
42. [Central retinal artery oclussion with visual acuity recovery. Case report].
- Author
-
Lima-Gómez V and Rojas-Dosal JA
- Subjects
- Female, Fluorescein Angiography, Humans, Middle Aged, Retinal Artery Occlusion diagnosis, Visual Acuity
- Abstract
Clinical Case: We present a case study of a patient with sudden visual loss, who had 20/200 visual acuity and macular edema at initial evaluation. Angiographies showed no interruption of vascular flow and in the visual field a central island of vision in the inferior hemifield was identified, surrounded by absolute scotoma., Discussion: Clinical aspect at the initial evaluation required a differential diagnosis between retinal and neural disease. The clinical approach used to integrate the retrospective diagnosis of central retinal artery occlusion is presented, and an explanation is proposed for the visual recovery after 3 months of visual loss (20/20 visual acuity)., Conclusion: Central retinal artery occlusion is a clinical diagnosis, but anatomical variants may modify the prognosis., Conclusions: Although the diagnosis of central retinal artery occlusion may be clinically evident, an angiography is required to evaluate the type of treatment to be instituted and to determine prognosis.
- Published
- 2007
43. [Rate of traumatic retinal injuries requiring urgent care. Is ocular fundus evaluation essential in the emergency room?].
- Author
-
Lima-Gómez V and Barrera-Fournier LV
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Cross-Sectional Studies, Eye Foreign Bodies diagnosis, Eye Injuries, Penetrating diagnosis, Fundus Oculi, Humans, Middle Aged, Retinal Detachment diagnosis, Retinal Detachment etiology, Retrospective Studies, Vitreous Hemorrhage diagnosis, Vitreous Hemorrhage etiology, Emergency Medical Services, Eye Injuries diagnosis, Ophthalmoscopy, Retina injuries
- Abstract
Background: A high rate of traumatic retinal injuries does not require a directed ocular fundus evaluation but those that deserve urgent care need it. The rate of traumatic retinal injuries that require urgent care was identified in order to learn whether there is a need of evaluating the ocular fundus in an emergency room., Methods: Patients with ocular trauma and ocular fundus evaluation who were referred to an Ophthalmology Service of a general hospital were included; patients with superficial foreign bodies were excluded. The rate of injuries that require urgent care (retinal detachment, intraocular foreign body) was identified and 95% confidence intervals (CI) were calculated., Results: One hundred fifty-three eyes of 148 patients (age 3-74 years, mean 26.4 years) were examined. Of 75 retinal injuries, 7 required urgent care (4.6%, 95% CI 1.3-7.9); the rate was 0.8% in closed globe trauma (95% CI 0-2.37) and 20.7 in open globe trauma (95% CI 5.9-35.5)., Conclusions: According to the rate of retinal injuries that would require urgent care in similar groups, in closed-globe trauma ocular fundus evaluation in the Emergency Room could be substituted by the evaluation of the fundus reflex; findings of any of these injuries in open-globe trauma does not modify the initial approach.
- Published
- 2007
44. [Ocular findings most frequently found in patients with allergic rhinoconjunctivitis].
- Author
-
Aguilar-Angeles D, Lima-Gómez V, Rojo-Gutiérrez MI, Bermejo-Guevara MA, González-Ibarra M, and López-Valladares KE
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Young Adult, Conjunctivitis, Allergic diagnosis, Conjunctivitis, Allergic etiology, Rhinitis, Allergic, Perennial complications
- Abstract
Background: Allergic etiology is suspected whenever a patient with conjunctivitis presents the typical clinical features; however, in ophthalmic practice, confirmation of the immune disease is uncommon. Ocular involvement is common in allergic rhinitis, and the current name of this entity is allergic rhinoconjunctivitis (ARC). Conjunctivitis diagnosis in ARC is inferred by the symptoms, but the most common ocular findings in patients with a confirmed allergic disease are unknown. The most common findings in allergic patients with ocular involvement were identified., Methods: Anterior segment of patients with an ARC diagnosis offered by an immunologist were evaluated, and the rates of the most common (whether considered related to allergy or not) were determined; 95% confidence intervals (CI) for rates were calculated., Results: One hundred and nineteen patients were evaluated, and the most common finding was conjunctival fornix edema (89.7%, 95% CI 83.5-94.7), followed by tarsal papillae (70.6%, 95% CI 62.4-78.8); the most common non-allergy-related finding was tear film deficiency (52.9%, 95% CI 43.9-61.9)., Conclusions: Conjunctival fornix edema was consistently more frequent than most of the signs used to diagnose allergic conjunctivitis in medical journals. It is suggested to intentionally look for this as recommended, in order to make a more easy diagnosis.
- Published
- 2007
45. [Ocular lesions associated with lid wounds with or without tearduct affection].
- Author
-
Lima-Gómez V and Mora-Pérez E
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Eye Injuries complications, Female, Humans, Infant, Male, Middle Aged, Retrospective Studies, Young Adult, Eye Injuries epidemiology, Eyelids injuries
- Abstract
Background: Lid wounds are traditionally repaired at primary care centers. The intervention of the ophthalmologist is reserved for cases with lachrymal system affection. High rates of ocular injuries associated with lid wounds have been reported (61%, American series; 44%, European). The purpose of the study was to identify the rate of ocular injuries in patients with lid wounds, in order to learn whether early ophthalmic evaluation is recommended, regardless of the lachrymal system status., Methods: A retrospective, transversal, observational, analytical, open study was carried out., Statistical Analysis: 95% confidence intervals (CI) for rates, z for rates, chi(2). Referrals for lid wounds between 1996 and 2002 were reviewed. The rate of ocular injuries and lachrymal system injuries was determined and compared with those reported. The rate of ocular injuries in patients with and without lachrymal system injuries was compared, and the rate of ocular injuries was compared with that of the lachrymal system., Results: Fifty-five patients were included (ages 1-80 years, average 26.3 years). Nine had lachrymal system injuries (16.4%, 95% CI 6.7-26.1), 37 had ocular injuries (67.3%, 95% CI 55-79.6). The rate was similar to the American study and higher than the European study (p < 0.001). Of the patients with lachrymal system injuries, 55% had ocular injuries, and 74% of patients without it had them (p < 0.05)., Conclusions: At a high rate (67.3%) of lid wounds, ocular injuries coexisted. Although a lid wound not affecting the lachrymal system may be repaired at a primary care center, early ophthalmic evaluation is recommended to rule out ocular globe damage.
- Published
- 2006
46. [Modification of the presentation of ocular trauma by age group in an urban Mexican population].
- Author
-
Lima-Gómez V and Góngora-Bobadilla VJ
- Subjects
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Male, Mexico, Middle Aged, Urban Population, Eye Injuries classification, Eye Injuries diagnosis
- Abstract
Introduction: We identified whether ocular trauma presentation, according to the system for classifying mechanical injuries of the eye, had modifications among different age groups, which could be useful as damage predictors during the initial evaluation of these patients., Material and Methods: Ocular trauma referrals between 1995 and 2003 were re-qualified according to the system for classifying mechanical injuries. Patients were divided into 5-year groups and the most frequent categories of type, grade, pupil and zone were determined by group. Mean age of each category and the rate of categories between groups were compared (ANOVA and Kruskal-Wallis, chi2 and odds ratio [OR])., Results: Five hundred sixty-six eyes of 551 patients were evaluated (age: 0.5-90 years, mean age: 27.7); mean age was lower for type B closed globe trauma and zone II (p < 0.05). There was a higher rate of grade 1 in patients > 60 years (OR 3.8), of grade 4 in patients < 54 years (OR 3.25) and of type B closed globe in patients > 20 years (OR 3.3). The remaining comparisons showed no clinical differences., Conclusions: There were no significant modifications in the presentation of most of the categories between age groups. Age difference was not useful as a predictor for detecting traumatic ocular damage.
- Published
- 2005
47. [Early diagnosis and risk factors associated with abdominal compartment syndrome].
- Author
-
Flores-Alvarez E, Avila-Cuevas GE, de la Torre-González JC, Rivera-Barragán V, López-Rodríguez JL, and Reynoso-Talamantes D
- Subjects
- Abdominal Injuries complications, Adult, Compartment Syndromes etiology, Compartment Syndromes mortality, Compartment Syndromes surgery, Decompression, Surgical, Female, Humans, Laparotomy, Male, Middle Aged, Pressure, Prospective Studies, Reoperation, Risk Factors, Time Factors, Abdomen, Compartment Syndromes diagnosis
- Abstract
Introduction: Abdominal compartment syndrome (ACS) is a clinical entity that develops after sustained and uncontrolled intraabdominal hypertension (IAHT). The ACS is clinically characterized by a massively distended abdomen and respiratory, cardiovascular, neurologic, and renal dysfunction., Objective: The goal of this study was to demonstrate the benefit of early diagnosis of intra-abdominal hypertension and ACS and to identify risk factors associated with mortality., Material and Methods: We used a prospective study that included all patients admitted to Hospital de Especialidades Miguel Hidalgo with known ACS risk factors between January 2002 and December 2003. All patients were submitted to systematic measurements of intra-abdominal pressure (IAP). Those patients with grade III-IV IAHT were treated with decompressive laparotomy., Results: Included in the study were 32 patients (23 males and 9 females). Mean age was 45.0 +/- 18.34 years. Twenty three patients developed IAHT grade I-II (group I) and nine developed grade IIIIV (group II). All group II patients were treated with abdominal decompression. The most common clinical entities associated were closed abdominal trauma (28%), hernias (15%), intestinal occlusions: (12.5%), acute pancreatitis (9.4%) and mesenteric ischemia (6.3%). Grade III-IV IAHT was statistically associated with reoperation (p = 0.038), acidosis (p = 0.003), anuria (p < 0.001) and sustained arterial hypotension (p = 0.004). The significant variables associated to mortality were anuria (p = 0.024) and grade III-IV IAHTA (0.017)., Conclusions: It is possible to make an early diagnosis of IAHT and ACS with an indirect measurement of IAP. The most important factors related to mortality are anuria and IAHT.
- Published
- 2005
48. [Functional prognosis in ocular trauma. Does visual deficiency help in localizing the injuries that cause it?].
- Author
-
Lima-Gómez V and García-Pacheco JM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Eye Injuries classification, Eye Injuries diagnosis, Female, Humans, Infant, Male, Middle Aged, Prevalence, Prognosis, Vision Disorders diagnosis, Visual Acuity, Eye Injuries complications, Vision Disorders etiology
- Abstract
Background: Prevalence of reported trauma-related blindness is 0.6% with almost half of serious ocular injuries involving the retina. Causes of visual deficit (VD) in ocular trauma were identified in patients with different grades (visual capacity), in order to determine the rate of poor functional prognosis at initial evaluation caused by posterior segment involvement and to identify a grade that could predict it., Methods: Ocular trauma referrals were re-qualified (1995-2003) according to the standardized classification. VD (grade >1) and zone were evaluated. The rate of VD and zone III with VD were determined. Injuries causing VD were identified and grouped by zone. The rate of these injuries was compared by zone, between each grade and the remaining, with chi2., Results: Five hundred fifty-seven eyes were included (mean age 27.7 years), 165 had VD (29.6%, CI 95% 25.8-33.4); 93 had zone III involvement (16.7%), 53 of whom had VD (9.5%, CI 95% 7.1-11.9%). Among injuries that caused VD (n = 323), 102 involved zone I (31.6%), 144 zone II (44.6%), and 77 zone III (23.8%). Injuries in zone III were more frequent in grade 5 (52%) than in the remaining groups (21.5%, p = 0.0005, OR 3.9)., Conclusions: In 90.5% of the eyes (CI 95%, 88.1-92.9), injuries caused VD by means of anterior segment involvement or did not cause it at all. A high rate of ocular trauma patients, even those with grade 5 at initial evaluation, may have an opportunity for visual recovery with early referral.
- Published
- 2004
49. [Value of ocular hypotony as a predictor of open-globe injury in patients with ocular trauma].
- Author
-
Lima-Gómez V and Cornejo-Mendoza AM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Infant, Intraocular Pressure, Male, Middle Aged, Retrospective Studies, Eye Injuries, Penetrating diagnosis, Ocular Hypotension diagnosis
- Abstract
Introduction: Ocular hypotony is an indirect open-globe injury sign that can be evaluated during primary care. A study was performed to ascertain the chances of a patient with ocular trauma and hypotony during initial evaluation of having open-globe injury compared with another patient without hypotony, and to estimate the value of hypotony as a predictor of open-globe injury., Material and Methods: Patients with ocular trauma evaluated between 1995 and 2003 with intraocular pressure records were included; patients with other causes of hypotony were excluded. Patients with hypotony were assigned to group 1 and those without hypotony to group 2. Rate of open-globe injury was compared between groups with chi2, odds ratio (OR), and 95% confidence intervals (95% CI)., Results: Three hundred sixty one patients (aged 1-90 years average age 26.3 years) were evaluated; 329 patients had closed-globe (91.1%) and 32, open-globe injury (8.9%). Thirty six were assigned to group 1 (10%) and 325 (90%) to group 2. Twenty three patients in group 1 had open-globe injury (63.9%) while nine in group 2 had open-globe injury (2.8%, p <0.001, OR 62.12, 95% CI 21.81-183.6). There was hypotony in 71.9% of eyes with open-globe injury and in 4% of eyes with closed-globe injury., Discussion: Although hypotony was not present in every open-globe injury, the chance of finding the latter when there was hypotony was 62 times greater than without it. Absence of hypotony might be a useful tool to rule out open-globe injury. It would be convenient to validate ocular hypotony as a diagnostic test of open-globe injury by means of a prospective study.
- Published
- 2004
50. [Lens opacity in diabetics. Prevalence and association to visual deficiency and retinopathy].
- Author
-
Lima-Gómez V and Ríos-González LC
- Subjects
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Cataract epidemiology, Diabetes Mellitus, Type 2 epidemiology, Diabetic Retinopathy epidemiology, Vision Disorders epidemiology
- Abstract
Introduction: Prevalence of lens opacity (LO) and its association with visual deficiency (VD, visual capacity < 20/40) and diabetic retinopathy (DR) were identified in diabetic patients to estimate rate of patients in whom VD could be lowered by surgery and whether DR rate was higher in patients with LO., Materials and Methods: Type 2 diabetics without prior ophthalmic examination were evaluated; rate of LO was determined and compared with those previously reported by z for rates. Patients with LO were assigned to group 1 and those without to group 2. Rates of VD and RD in each group were compared by chi2 test and odds ratio (OR)., Results: Three hundred thirteen patients were evaluated (age range 41-87 years, mean 58.5 years) and mean diabetes duration mean was 7.8 years. LO rate was higher than expected (49%, p < 0.001): 109 patients in group 1 (53.4%) and 18 in group 2 (16.5%) had VD (p < 0.001, OR 5.59), while 46 patients in group 1 and 13 in group 2 (11.9%) had DR, which was not clinically different (p = 0.03, OR 2.15)., Discussion: Presence of LO should be considered during ophthalmic evaluation in diabetics; VD could be erroneously attributed to DR, whose detection could be limited by LO. Should LO cause significant visual impairment, extraction would help improve vision if there is no DR and would help to have an adequate optic medium to follow-up and treat the latter, if it is present.
- Published
- 2004
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