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Your search keyword '"Rhodiola quadrifida"' showing total 2 results
Start Over Descriptor "Rhodiola quadrifida" Publisher pharmaceutical society of japan
2 results on '"Rhodiola quadrifida"'

1. Bioactive Constituents of Chinese Natural Medicines. II. Rhodiolae Radix. (1). Chemical Structures and Antiallergic Activity of Rhodiocyanosides A and B from the Underground Part of Rhodiola quadrifida (PALL.) FISCH. et MEY. (Crassulaceae)

Author

Hiromi Shimada, Nobutoshi Murakami, Johji Yamahara, Masayuki Yoshikawa, Hiroshi Shimoda, and Hisashi Matsuda

Subjects
Male, Magnetic Resonance Spectroscopy, Rhodioloside, Histamine Release, Plant Roots, chemistry.chemical_compound, Anti-Allergic Agents, Cromolyn Sodium, Drug Discovery, Botany, Animals, Radix, Anti-Asthmatic Agents, Glycosides, Rats, Wistar, Peritoneal Cavity, Tricetin, chemistry.chemical_classification, Plants, Medicinal, Gossypetin, biology, Passive Cutaneous Anaphylaxis, Glycoside, Exudates and Transudates, General Chemistry, General Medicine, biology.organism_classification, Rats, Crassulaceae, chemistry, Passive cutaneous anaphylaxis test, Rhodiola quadrifida
Abstract

Two bioactive cyanoglycosides, rhodiocyanosides A and B, and two oligoglycosides, rhodioflavonoside [gossypetin 7-O-beta-D-glucopyranosyl(1--3)-alpha-L-rhamnopyranoside] and rhodiooctanoside [octyl alpha-L-arabinopyranosyl(1--6) beta- D-glucopyranoside), were isolated from the Chinese natural medicine "Si Lie Hong Jing Tian" (Shiretsukoukeiten in Japanese), the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey., together with four known compounds: rhodioloside, n-hexyl beta-D-glucopyranoside, gossypetin 7-O-alpha-L-rhamnopyranoside, and tricetin. The chemical structures of new glycosides were determined on the basis of chemical and physicochemical evidence. Rhodiocyanosides A and B exhibited inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-2,4-dinitrophenyl IgE. Additionally, rhodiocyanoside A, the major constituent of this natural medicine, was also found to show antiallergic activity in a passive cutaneous anaphylaxis test in rat.

Published
1996

2. Rhodiocyanosides A and B, new antiallergic cyanoglycosides from chinese natural medicine 'Si Lie Hong Jing Tian', the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey

Author

Hisashi Matsuda, Nobutoshi Murakami, Hiroshi Shimoda, Masayuki Yoshikawa, Hiromi Shimada, and Johji Yamahara

Subjects
Chemical Phenomena, Molecular Sequence Data, Spectrometry, Mass, Fast Atom Bombardment, Pharmacognosy, Histamine Release, Plant Roots, chemistry.chemical_compound, Drug Discovery, Peritoneal exudate, Hypersensitivity, Animals, Glycosides, Natural medicine, chemistry.chemical_classification, Gossypetin, Passive anaphylaxis, biology, Traditional medicine, Chemistry, Physical, Glycoside, General Chemistry, General Medicine, biology.organism_classification, Rats, Crassulaceae, Carbohydrate Sequence, chemistry, Rhodiola quadrifida, Drugs, Chinese Herbal
Abstract

Two new antiallergic cyanoglycosides named rhodiocyanosides A and B were isolated from the Chinese natural medicine "Si Lie Hong Jing Tian" (Shiretsukoukeiten in Japanese), the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey., together with two new glycosides, octyl alpha-L-arabinopyranosyl(1-6)-beta-D-glucopyranoside and gossypetin 7-O-beta-D-glucopyranosyl(1-3)-alpha-L-rhamnopyranoside. Their chemical structures were determined on the basis of chemical and physicochemical evidence. Rhodiocyanosides A and B exhibited inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE. In addition, rhodiocyanoside A was found to inhibit the PCA reaction in rats.

Published
1995

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