1. Assessment of risk factors for postoperative cognitive dysfunction after coronary artery bypass surgery: a single-center retrospective cohort study
- Author
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Yanwu Jin, Mengjie Liu, Yalei Gao, Ming Hou, Hai Feng, changping Gu, Yongtao Sun, Ting Zou, Yuelan Wang, Min Zhang, and Juan Li
- Subjects
Adult ,Male ,Trail Making Test ,Biophysics ,Coronary artery bypass grafting ,030204 cardiovascular system & hematology ,Biochemistry ,03 medical and health sciences ,Coronary artery bypass surgery ,Postoperative Complications ,0302 clinical medicine ,Wisconsin Card Sorting Test ,030202 anesthesiology ,medicine ,Humans ,Coronary Artery Bypass ,Postoperative cognitive dysfunction ,Molecular Biology ,Research Articles ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Incidence ,Pharmacology & Toxicology ,Retrospective cohort study ,Cell Biology ,Neuropsychological test ,Middle Aged ,medicine.disease ,Systemic inflammatory response syndrome ,Stenosis ,Risk factors ,Cardiovascular System & Vascular Biology ,Anesthesia ,Female ,Cognition Disorders ,business ,Neuroscience - Abstract
Aim: To find out risk factors for postoperative cognitive dysfunction (POCD) after coronary artery bypass grafting (CABG), and to provide basis for clinical prevention of POCD. A total of 88 patients who underwent CABG were surveyed with Telephone Questionnaire (TICS-M) for their cognitive impairment after 3, 7, 21, 90, 180 days post-surgery. The occurrence of POCD was diagnosed by Neuropsychological Battery which included Vocabular Learning Test (VLT), Wisconsin Card Sorting Test (WCST), Trail Making Test (TMT) and Symbol Digit Modalities Test (SDMT). The preoperative, intraoperative and postoperative risk factors were assessed by the χ2 or t test. Multivariate analysis was used to study the correlation between the risk factors and the occurrence of POCD. Age, aortic plaque, carotid artery stenosis, cerebrovascular disease, anesthesia time, the rate of decline in intraoperative hemoglobin concentration (ΔHb) and systemic inflammatory response syndrome (SIRS) score on postoperative day 2 had statistically significant (P 1, P
- Published
- 2021