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AIM: To investigate the clinical efficacy of intravitreal injection of Ranibizumab and 577nm laser in the treatment of retinal vein occlusion combined with macular edema. METHODS: Totally 64 patients(64 eyes)with retinal vein occlusion accompanied by macular edema were treated in our hospital from June 2014 to March 2017. Among them, 40 cases(40 eyes)were in the central retinal vein occlusion group, 24 cases(24 eyes)were in the branch retinal vein occlusion group. They were treated with intravitreal injection of ranibizumab 0.5mg, and the laser photocoagulation of 577nm was performed at 5 to 7d after injection. Meanwhile, 42 patients who did not wish to be treated with injection were treated with laser treatment only. The changes of the indexes before and after treatment were compared. RESULTS: The average number of blocking group repeated injection of branch retinal vein for 1.71±0.79, while the average number of patients with repeated injection of central retinal vein occlusion was 2.11±0.80. All patients requiring repeated injections interval was greater than 30d. At 1mo after treatment, there was no patients with decreased visual acuity in branch retinal vein occlusion group, while there were 6 eyes with that in central retinal vein occlusion group, 14 eyes in simply laser group. The mean best corrected visual acuity(LogMAR)of the three groups was 0.87±0.60, 0.57±0.48 and 0.54±0.32, respectively, were significantly lower than that before treatment(1.26±0.53, 0.86±0.39, 0.76±0.26; PPCONCLUSION: Intravitreal injection of ranibizumab combined with 577nm laser treatment can greatly enhance the visual acuity, effective decrease macular retinal thickness in patients with retinal vein occlusion and macular edema.

AIM:To investigate the effects of the MUC5AC levels and ocular function of the patients with glaucoma and cataract with combined surgery. METHODS: Twenty-eight patients treated with glaucoma and cataract combined surgery were chosen as the observation group from December 2011 to June 2014 in our hospital, and other 28 cases of glaucoma and cataract did not undergo surgical treatment were selected as the control group, 30 healthy subjects were as healthy control group. the MUC5AC level and ocular surface score of the three subjects before surgery 1d, after 3 and 6mo were compared.RESULTS: The NUC5AC of the two groups of patients was significantly lower than that of the healthy control group before surgery(PPPPPPCONCLUSION: To treat the patients with glaucoma and cataract with combined surgery, the level of MUC5AC can temporary decrease. Ocular function score can temporary increase in, but after 3mo, it can be gradually improved.