1. Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor
- Author
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Paolo Gasparini, Maik Behrens, Xevi Biarnés, Stephan Born, Alessandro Marchiori, Paolo Carloni, Alejandro Giorgetti, Wolfgang Meyerhof, Carmela Lanzara, Anne Brockhoff, Biarnés, Xevi, Marchiori, Alessandro, Giorgetti, Alejandro, Lanzara, Carmela, Gasparini, Paolo, Carloni, Paolo, Born, Stephan, Brockhoff, Anne, Behrens, Maik, and Meyerhof, Wolfgang
- Subjects
Models, Molecular ,Genetics and Molecular Biology (all) ,Secondary ,Intracellular Space ,Computational Biology/Macromolecular Structure Analysis ,Plasma protein binding ,Ligands ,Biochemistry ,Molecular Biology/Bioinformatics ,Protein Structure, Secondary ,Receptors, G-Protein-Coupled ,Protein structure ,GPCR ,Models ,Receptors ,Site-Directed ,Receptor ,Multidisciplinary ,Medicine (all) ,Phenylthiourea ,calcium imaging ,TAS2R38 ,Biochemistry/Bioinformatics ,Medicine ,ddc:500 ,Drug ,Research Article ,Human ,Protein Binding ,Biophysics/Theory and Simulation ,Agonist ,Protein Structure ,medicine.drug_class ,Science ,Molecular Sequence Data ,bitter taste ,Ligand ,Computational Biology/Protein Structure Prediction ,Biology ,Amino Acid Sequence ,Calcium ,Cell Line ,Computational Biology ,Dose-Response Relationship, Drug ,Humans ,Mutagenesis, Site-Directed ,Agricultural and Biological Sciences (all) ,Biochemistry, Genetics and Molecular Biology (all) ,Dose-Response Relationship ,G-Protein-Coupled ,Cell surface receptor ,medicine ,Binding site ,G protein-coupled receptor ,Molecular ,modeling ,mutagenesis ,Mutagenesis - Abstract
PLoS one 5(8), e12394 (2010). doi:10.1371/journal.pone.0012394, Published by PLoS [u.a.], Lawrence, Kan.
- Published
- 2010
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