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Start Over Author "Huang, Shoujun" Publisher public library of science
1 results on '"Huang, Shoujun"'

1. Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover.

Author

Huang, Shoujun, Zhang, Zhao, Zhang, Chunxia, Lv, Xiangdong, Zheng, Xiudeng, Chen, Zhenping, Sun, Liwei, Wang, Hailong, Zhu, Yuanxiang, Zhang, Jing, Yang, Shuyan, Lu, Yi, Sun, Qinmiao, Tao, Yi, Liu, Feng, Zhao, Yun, and Chen, Dahua

Subjects
*LIGASES, *HEDGEHOG signaling proteins, *CELLULAR signal transduction, *UBIQUITIN, *EMBRYOLOGY
Abstract

Protein turnover of Patched, the Hedgehog receptor and key negative regulator of Hedgehog signaling, is controlled by the ubiquitin E3 ligase, Smurf, in a manner that depends on activation of signal transducer, Smoothened. [ABSTRACT FROM AUTHOR]

Published
2013
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