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In the context of extensive disciplinary integration, researchers worldwide have increasingly focused on musical ability. However, despite the wide range of available music ability tests, there remains a dearth of validated tests applicable to China. The Music Ear Test (MET) is a validated scale that has been reported to be potentially suitable for cross-cultural distribution in a Chinese sample. However, no formal translation and cross-cultural reliability/validity tests have been conducted for the Chinese population in any of the studies using the Music Ear Test. This study aims to assess the factor structure, convergence, predictiveness, and validity of the Chinese version of the MET, based on a large sample of Chinese participants (n≥1235). Furthermore, we seek to determine whether variables such as music training level, response pattern, and demographic data such as gender and age have intervening effects on the results. In doing so, we aim to provide clear indications of musical aptitude and expertise by validating an existing instrument, the Music Ear Test, and provide a valid method for further understanding the musical abilities of the Chinese sample. [ABSTRACT FROM AUTHOR]

The order of the affiliations is incorrect. Please view the correct affiliation order below:Xiaoyu Wang2, Xiubo Ren2, Shidan Wang 2, Dan Yang2, Shilin Liu2, Meihui Li2, Mingyi Yang2, Yintong Liu2, Qiujian Xu1,2*1 School of Arts and Design, Yanshan University, 066000, Qinhuangdao, China, 2 Music College, Catholic University of Daegu, 13–13 Hayang-ro, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do, Republic of Korea.By Xiaoyu Wang; Xiubo Ren; Shidan Wang; Dan Yang; Shilin Liu; Meihui Li; Mingyi Yang; Yintong Liu and Qiujian XuReported by Author; Author; Author; Author; Author; Author; Author; Author; Author [Extracted from the article]

Objective: To investigate the effect and mechanism of SB525334 on self-renewal, migration and invasion of ovarian cancer stem cells. Methods: ALDHhigh-expressing cancer stem cells (CSCs) were isolated from human ovarian cancer cell line SKOV-3 by flow cytometry and treated with 2μg/mL SB525334 for 6h. The sphere forming assay was used to detect the ability of self-renewal of CSCs and the colony formation assay was used to detect the tumorigenicity in vitro. Transwell migration and invasion assay were used to detect the migration and invasion ability of CSCs. To further explore the mechanism, real-time quantitative PCR and flow cytometry were used to detect the mRNA and protein expression of TGF-β, Smad2, Smad3, phosphorylated Smad2, phosphorylated Smad3 and Smad4, respectively. Expressions of epithelial-mesenchymal transition (EMT)-related genes E-cadherin, Snail, Vimentin were also assessed. Results: The self-renewal ability, tumorigenicity in vitro, migration and invasion ability of CSCs were significantly attenuated after SB525334 treatment. The expressions of TGF-β, phosphorylated Smad2, phosphorylated Smad3, Snail, and Vimentin were decreased, while Smad4 and E-cadherin expressions were increased. Conclusion: SB525334 may inhibit the self-renewal, invasion and migration of ovarian CSCs by blocking the TGF-β/Smad/EMT pathway. [ABSTRACT FROM AUTHOR]