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Your search keyword '"Assaad Semaan"' showing total 2 results
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2 results on '"Assaad Semaan"'

1. The role of frozen section in surgical staging of low risk endometrial cancer.

Author

Sanjeev Kumar, Sudeshna Bandyopadhyay, Assaad Semaan, Jay P Shah, Haider Mahdi, Robert Morris, Adnan Munkarah, and Rouba Ali-Fehmi

Subjects
Medicine, Science
Abstract

BACKGROUND: The role of frozen section (FS) in intraoperative decision making for surgical staging of endometrial cancer is controversial. Objective of this study is to assess the agreement rate between the FS and paraffin section (PS); and the potential impact of the role of FS in the intra-operative decision making for the complete surgical staging in low risk endometrial cancer. METHODS: This is a retrospective analysis of patients diagnosed with intra-operative FS stage I, grade I or II endometrial cancer from 1995-2004. FS results were compared with final pathology results with regard to tumor grade, depth of myometrial invasion, cervical involvement, lymphovascular invasion, and lymph node involvement. Agreement statistic with kappa was calculated using SPSS statistical software. Categorical variables were tested using chi-square test with p value of ≤0.05 being statistically significant. RESULTS: Of the 457 patients with endometrial cancer, 146 were evaluated by intra-operative FS and met inclusion criteria. FS results were in disagreement with permanent section in 35% for the grade (kappa 0.58, p = 0.003), 28% for depth of myometrial invasion (kappa 0.61, p

Published
2011
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2. The role of frozen section in surgical staging of low risk endometrial cancer

Author

Assaad Semaan, Robert T. Morris, Haider Mahdi, Sanjeev Kumar, Sudeshna Bandyopadhyay, Rouba Ali-Fehmi, Adnan R. Munkarah, and Jay P. Shah

Subjects
Lymphovascular invasion, medicine.medical_treatment, lcsh:Medicine, Cervix Uteri, Metastasis, Surgical oncology, Pathology, Frozen Sections, Stage (cooking), lcsh:Science, Lymph node, Aged, 80 and over, Multidisciplinary, Obstetrics and Gynecology, Middle Aged, medicine.anatomical_structure, Oncology, Paraffin, Lymphatic Metastasis, Myometrium, Medicine, Female, Radiology, Endometrial Carcinoma, Research Article, Adult, Risk, medicine.medical_specialty, Histology, Clinical Pathology, Histopathology, Young Adult, Diagnostic Medicine, Uterine cancer, medicine, Humans, Neoplasm Invasiveness, Biology, Aged, Lymphatic Vessels, Neoplasm Staging, business.industry, Endometrial cancer, lcsh:R, Gynecologic Cancers, Cancers and Neoplasms, medicine.disease, Endometrial Neoplasms, Surgery, Anatomical Pathology, Lymphadenectomy, lcsh:Q, Neoplasm Grading, business, Gynecological Tumors
Abstract

Background The role of frozen section (FS) in intraoperative decision making for surgical staging of endometrial cancer is controversial. Objective of this study is to assess the agreement rate between the FS and paraffin section (PS); and the potential impact of the role of FS in the intra-operative decision making for the complete surgical staging in low risk endometrial cancer. Methods This is a retrospective analysis of patients diagnosed with intra-operative FS stage I, grade I or II endometrial cancer from 1995–2004. FS results were compared with final pathology results with regard to tumor grade, depth of myometrial invasion, cervical involvement, lymphovascular invasion, and lymph node involvement. Agreement statistic with kappa was calculated using SPSS statistical software. Categorical variables were tested using chi-square test with p value of ≤0.05 being statistically significant. Results Of the 457 patients with endometrial cancer, 146 were evaluated by intra-operative FS and met inclusion criteria. FS results were in disagreement with permanent section in 35% for the grade (kappa 0.58, p = 0.003), 28% for depth of myometrial invasion (kappa 0.61, p

Published
2011

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