1. Repeated Measurement of the Intermountain Risk Score Enhances Prognostication for Mortality
- Author
-
Tami L Bair, Joseph B. Muhlestein, Brianna S. Ronnow, Rami Alharethi, Benjamin D. Horne, Kurt R. Jensen, Heidi T May, Deborah Budge, Kimberly D. Brunisholz, Abdallah G. Kfoury, Donald L Lappe, T. Jared Bunch, Brian Whisenant, and Jeffrey L. Anderson
- Subjects
Male ,Epidemiology ,Myocardial Infarction ,lcsh:Medicine ,Cardiovascular ,Endocrinology ,Risk Factors ,Chronic Kidney Disease ,Myocardial infarction ,lcsh:Science ,Stroke ,Aged, 80 and over ,Multidisciplinary ,Framingham Risk Score ,medicine.diagnostic_test ,Mortality rate ,Hazard ratio ,Complete blood count ,Hematology ,Middle Aged ,Prognosis ,Nephrology ,Medicine ,Female ,Research Article ,Adult ,medicine.medical_specialty ,Adolescent ,Clinical Research Design ,Young Adult ,Internal medicine ,medicine ,Humans ,Mortality ,Biology ,Cardiovascular Disease Epidemiology ,Survival analysis ,Aged ,Heart Failure ,Diabetic Endocrinology ,Population Biology ,business.industry ,lcsh:R ,medicine.disease ,Survival Analysis ,Confidence interval ,Surgery ,Biomarker Epidemiology ,lcsh:Q ,business - Abstract
Background The Intermountain Risk Score (IMRS), composed of the complete blood count (CBC) and basic metabolic profile (BMP), predicts mortality and morbidity in medical and general populations. Whether longitudinal repeated measurement of IMRS is useful for prognostication is an important question for its clinical applicability. Methods Females (N = 5,698) and males (N = 5,437) with CBC and BMP panels measured 6 months to 2.0 years apart (mean 1.0 year) had baseline and follow-up IMRS computed. Survival analysis during 4.0±2.5 years (maximum 10 years) evaluated mortality (females: n = 1,255 deaths; males: n = 1,164 deaths) and incident major events (myocardial infarction, heart failure [HF], and stroke). Results Both baseline and follow-up IMRS (categorized as high-risk vs. low-risk) were independently associated with mortality (all p
- Published
- 2013
- Full Text
- View/download PDF