1. Serum Levels of Surfactant Proteins in Patients with Combined Pulmonary Fibrosis and Emphysema (CPFE).
- Author
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Andriana I Papaioannou, Konstantinos Kostikas, Effrosyni D Manali, Georgia Papadaki, Aneza Roussou, Aris Spathis, Argyro Mazioti, Ioannis Tomos, Ilias Papanikolaou, Stelios Loukides, Kyriakos Chainis, Petros Karakitsos, Matthias Griese, and Spyros Papiris
- Subjects
Medicine ,Science - Abstract
Emphysema and idiopathic pulmonary fibrosis (IPF) present either per se or coexist in combined pulmonary fibrosis and emphysema (CPFE). Serum surfactant proteins (SPs) A, B, C and D levels may reflect lung damage. We evaluated serum SP levels in healthy controls, emphysema, IPF, and CPFE patients and their associations to disease severity and survival.122 consecutive patients (31 emphysema, 62 IPF, and 29 CPFE) and 25 healthy controls underwent PFTs, ABG-measurements, 6MWT and chest HRCT. Serum levels of SPs were measured. Patients were followed-up for 1-year.SP-A and SP-D levels differed between groups (p = 0.006 and p
- Published
- 2016
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