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Your search keyword '"Mohamed, El Sanharawi"' showing total 2 results
Start Over Author "Mohamed, El Sanharawi" Publisher public library of science (plos)
2 results on '"Mohamed, El Sanharawi"'

1. In vivo imaging of palisades of Vogt in dry eye versus normal subjects using en-face spectral-domain optical coherence tomography.

Author

Wajdene Ghouali, Rachid Tahiri Joutei Hassani, Zoubir Djerada, Hong Liang, Mohamed El Sanharawi, Antoine Labbé, and Christophe Baudouin

Subjects
Medicine, Science
Abstract

To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients.Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT. En-face OCT images of the corneoscleral limbus were acquired in four quadrants (inferior, superior, nasal and temporal) and then were analyzed semi-quantitatively according to whether or not palisades of Vogt (POV) were visible. En-face OCT images were then compared to in vivo confocal microscopy (IVCM) in eleven eyes of 7 healthy and dry eye patients.En-face SD-OCT showed POV as a radially oriented network, located in superficial corneoscleral limbus, with a good correlation with IVCM features. It provided an easy and reproducible identification of POV without any special preparation or any direct contact, with a grading scale from 0 (no visualization) to 3 (high visualization). The POV were found predominantly in superior (P

Published
2017
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2. In vivo imaging of palisades of Vogt in dry eye versus normal subjects using en-face spectral-domain optical coherence tomography

Author

Antoine Labbé, Hong Liang, Rachid Tahiri Joutei Hassani, Mohamed El Sanharawi, Zoubir Djerada, Christophe Baudouin, and Wajdene Ghouali

Subjects
Male, 0301 basic medicine, Eye Diseases, genetic structures, In vivo confocal microscopy, lcsh:Medicine, Diagnostic Radiology, Cornea, 0302 clinical medicine, Animal Cells, Corneoscleral Limbus, Medicine and Health Sciences, Image Processing, Computer-Assisted, Medicine, Stem Cell Niche, lcsh:Science, Tomography, Microscopy, Confocal, Multidisciplinary, medicine.diagnostic_test, Radiology and Imaging, Stem Cells, Middle Aged, In Vivo Imaging, medicine.anatomical_structure, Regression Analysis, Dry Eye Syndromes, Female, Anatomy, Cellular Types, Tomography, Optical Coherence, Preclinical imaging, Research Article, Adult, medicine.medical_specialty, Imaging Techniques, Ocular Anatomy, Spectral domain, Limbus Corneae, Research and Analysis Methods, Young Adult, 03 medical and health sciences, Optical coherence tomography, Ocular System, Diagnostic Medicine, Ophthalmology, Healthy control, Humans, Aged, Demography, business.industry, lcsh:R, Biology and Life Sciences, Reproducibility of Results, Cell Biology, eye diseases, 030104 developmental biology, Multivariate Analysis, 030221 ophthalmology & optometry, Eyes, lcsh:Q, sense organs, business, Head
Abstract

Purpose To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients. Patients and methods Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT. En-face OCT images of the corneoscleral limbus were acquired in four quadrants (inferior, superior, nasal and temporal) and then were analyzed semi-quantitatively according to whether or not palisades of Vogt (POV) were visible. En-face OCT images were then compared to in vivo confocal microscopy (IVCM) in eleven eyes of 7 healthy and dry eye patients. Results En-face SD-OCT showed POV as a radially oriented network, located in superficial corneoscleral limbus, with a good correlation with IVCM features. It provided an easy and reproducible identification of POV without any special preparation or any direct contact, with a grading scale from 0 (no visualization) to 3 (high visualization). The POV were found predominantly in superior (P

Published
2017
Full Text
View/download PDF

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