1. Gender and Age Interact to Affect Early Outcome after Intracerebral Hemorrhage
- Author
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David L. McDonagh, Marisa C. Gray, Michael L. James, Briana Roulhac-Wilson, Barbara Phillips-Bute, Wei Sun, Daniel T. Laskowitz, Peter G. Kranz, Odera A. Umeano, and Claire E. Hailey
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,lcsh:Medicine ,Sex Factors ,medicine ,Humans ,cardiovascular diseases ,Risk factor ,lcsh:Science ,Prospective cohort study ,Stroke ,Aged ,Cerebral Hemorrhage ,Probability ,Retrospective Studies ,Neurologic Examination ,Intracerebral hemorrhage ,Univariate analysis ,Multidisciplinary ,business.industry ,lcsh:R ,Age Factors ,Retrospective cohort study ,Recovery of Function ,Middle Aged ,Prognosis ,medicine.disease ,Multivariate Analysis ,Cohort ,Population study ,Female ,lcsh:Q ,business ,Research Article - Abstract
Background Intracerebral hemorrhage (ICH) is a common and devastating form of cerebrovascular disease. In ICH, gender differences in outcomes remain relatively understudied but have been examined in other neurological emergencies. Further, a potential effect of age and gender on outcomes after ICH has not been explored. This study was designed to test the hypothesis that age and gender interact to modify neurological outcomes after ICH. Methods Adult patients admitted with spontaneous primary supratentorial ICH from July 2007 through April 2010 were assessed via retrospective analysis of an existing stroke database at Duke University. Univariate analysis of collected variables was used to compare gender and outcome. Unfavorable outcome was defined as discharge to hospice or death. Using multivariate regression, the combined effect of age and gender on outcome after ICH was analyzed. Results In this study population, women were younger (61.1+14.5 versus 65.8+17.3 years, p=0.03) and more likely to have a history of substance abuse (35% versus 8.9%, p more...
- Published
- 2013
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