Search

Your search keyword '"Roberto Ferrero"' showing total 2 results
Start Over Author "Roberto Ferrero" Publisher public library of science (plos)
2 results on '"Roberto Ferrero"'

1. The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life.

Author

Annalisa Deodati, Josepmaría Argemí, Daniela Germani, Antonella Puglianiello, Anna Alisi, Cristiano De Stefanis, Roberto Ferrero, Valerio Nobili, Tomás Aragón, and Stefano Cianfarani

Subjects
Medicine, Science
Abstract

Early life events are associated with the susceptibility to chronic diseases in adult life. Perturbations of endoplasmic reticulum (ER) homeostasis activate the unfolded protein response (UPR), which contributes to the development of metabolic alterations. Our aim was to evaluate liver UPR in an animal model of intrauterine growth restriction (IUGR). A significantly increased expression of X-box binding protein-1 spliced (XBP1s) mRNA (p

Published
2018
Full Text
View/download PDF

2. The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life

Author

Josepmaria Argemi, Daniela Germani, Antonella Puglianiello, Tomás J. Aragón, Cristiano De Stefanis, Valerio Nobili, Roberto Ferrero, Anna Alisi, Stefano Cianfarani, and Annalisa Deodati

Subjects
0301 basic medicine, Leptin, Male, X-Box Binding Protein 1, Adult life, Messenger, Unfolded protein response (UPR), lcsh:Medicine, Fatty Acids, Nonesterified, Endoplasmic Reticulum, Rats, Sprague-Dawley, Pregnancy, lcsh:Science, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Glucose tolerance test, Multidisciplinary, Fetal Growth Retardation, medicine.diagnostic_test, Fatty Acids, Aspartate-Ammonia Ligase, Settore MED/38, Liver, Lipogenesis, Metabolome, Female, medicine.medical_specialty, Biology, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, medicine, Animals, RNA, Messenger, Disease Models, Animal, Gene Expression Regulation, Glucose Tolerance Test, Rats, Unfolded Protein Response, Animal, Endoplasmic reticulum, lcsh:R, medicine.disease, 030104 developmental biology, Endocrinology, Gluconeogenesis, Chronic diseases, Disease Models, Nonesterified, Unfolded protein response, RNA, lcsh:Q, Sprague-Dawley, Steatosis, Homeostasis
Abstract

Early life events are associated with the susceptibility to chronic diseases in adult life. Perturbations of endoplasmic reticulum (ER) homeostasis activate the unfolded protein response (UPR), which contributes to the development of metabolic alterations. Our aim was to evaluate liver UPR in an animal model of intrauterine growth restriction (IUGR). A significantly increased expression of X-box binding protein-1 spliced (XBP1s) mRNA (p

Published
2018

Catalog

Books, media, physical & digital resources
See catalog results