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Start Over Author "Ruyi Liang" Publisher public library of science (plos)
1 results on '"Ruyi Liang"'

1. MicroRNA-21 Regulates PI3K/Akt/mTOR Signaling by Targeting TGFβI during Skeletal Muscle Development in Pigs.

Author

Lijing Bai, Ruyi Liang, Yalan Yang, Xinhua Hou, Zishuai Wang, Shiyun Zhu, Chuduan Wang, Zhonglin Tang, and Kui Li

Subjects
Medicine, Science
Abstract

MicroRNAs (miRNAs), which are short (22-24 base pairs), non-coding RNAs, play critical roles in myogenesis. Using Solexa deep sequencing, we detected the expression levels of 229 and 209 miRNAs in swine skeletal muscle at 90 days post-coitus (E90) and 100 days postnatal (D100), respectively. A total of 138 miRNAs were up-regulated on E90, and 31 were up-regulated on D100. Of these, 9 miRNAs were selected for the validation of the small RNA libraries by quantitative RT-PCR (RT-qPCR). We found that miRNA-21 was down-regulated by 17-fold on D100 (P

Published
2015
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