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2 results on '"Sanja Medenica"'

1. Follicular fluid thyroid autoantibodies, thyrotropin, free thyroxine levels and assisted reproductive technology outcome.

Author

Sanja Medenica, Eliana Garalejic, Biljana Arsic, Biljana Medjo, Dragana Bojovic Jovic, Dzihan Abazovic, Rade Vukovic, and Milos Zarkovic

Subjects
Medicine, Science
Abstract

OBJECTIVE:Although there are substantial data linking thyroid autoimmunity (TAI) and infertility, data regarding assisted reproductive technology (ART) outcomes and TAI markers in follicular fluid (FF) of women undergoing ART are scarce. Objective of the study was to assess the association of the levels of thyroid autoantibodies in FF and ART outcome expressed as the achieved pregnancies. METHODS:This study enrolled 52 women undergoing ART (26 TAI positive subjects and 26 age and body mass index matched TAI negative controls). Blood samples were drawn before the initiation of protocol for controlled ovarian stimulation, and thyrotropin (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroid peroxidase antibodies (TPOAbs) and thyroglobulin antibodies (TgAbs) levels were measured. TSH, fT4, TPOAbs, TgAbs and progesterone levels were also measured in FF. RESULTS:There were no significant differences between the groups regarding mean levels of FF TSH and FF fT4. Statistically significant correlation was discovered regarding the levels of serum and FF TPOAbs (0,961, p

Published
2018
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2. Follicular fluid thyroid autoantibodies, thyrotropin, free thyroxine levels and assisted reproductive technology outcome

Author

Rade Vukovic, Milos Zarkovic, Dragana Bojovic Jovic, Eliana Garalejic, Sanja Medenica, Biljana Arsic, Dzihan Abazovic, and Biljana Medjo

Subjects
Physiology, Maternal Health, Peptide Hormones, medicine.medical_treatment, Thyroid Gland, Thyrotropin, lcsh:Medicine, Miscarriage, Assisted Reproductive Technology, Biochemistry, 0302 clinical medicine, Pregnancy, Animal Cells, Immune Physiology, Female Infertility, Medicine and Health Sciences, Medicine, Prospective Studies, lcsh:Science, Thyroid, 2. Zero hunger, Immune System Proteins, 030219 obstetrics & reproductive medicine, Multidisciplinary, biology, Obstetrics and Gynecology, Anti-thyroid autoantibodies, humanities, 3. Good health, medicine.anatomical_structure, OVA, Triiodothyronine, Female, Anatomy, Cellular Types, Research Article, Adult, Infertility, medicine.medical_specialty, Reproductive Techniques, Assisted, Urology, Immunology, Endocrine System, 030209 endocrinology & metabolism, Antibodies, Young Adult, 03 medical and health sciences, Thyroid-stimulating hormone, Thyroid peroxidase, Internal medicine, Humans, Thyroid-Stimulating Hormone, Autoantibodies, business.industry, lcsh:R, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, Follicular fluid, Hormones, Follicular Fluid, Pregnancy Complications, Thyroxine, Germ Cells, Endocrinology, Case-Control Studies, Oocytes, biology.protein, Women's Health, Thyroglobulin, lcsh:Q, business, human activities
Abstract

Objective Although there are substantial data linking thyroid autoimmunity (TAI) and infertility, data regarding assisted reproductive technology (ART) outcomes and TAI markers in follicular fluid (FF) of women undergoing ART are scarce. Objective of the study was to assess the association of the levels of thyroid autoantibodies in FF and ART outcome expressed as the achieved pregnancies. Methods This study enrolled 52 women undergoing ART (26 TAI positive subjects and 26 age and body mass index matched TAI negative controls). Blood samples were drawn before the initiation of protocol for controlled ovarian stimulation, and thyrotropin (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroid peroxidase antibodies (TPOAbs) and thyroglobulin antibodies (TgAbs) levels were measured. TSH, fT4, TPOAbs, TgAbs and progesterone levels were also measured in FF. Results There were no significant differences between the groups regarding mean levels of FF TSH and FF fT4. Statistically significant correlation was discovered regarding the levels of serum and FF TPOAbs (0,961, p

Published
2018

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