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Start Over Author "Ting-Ting Tang" Publisher public library of science (plos)
2 results on '"Ting-Ting Tang"'

1. Correction: Impaired Thymic Export and Apoptosis Contribute to Regulatory T-Cell Defects in Patients with Chronic Heart Failure.

Author

Ting-Ting Tang, Zheng-Feng Zhu, Jun Wang, Wen-Cai Zhang, Xin Tu, Hong Xiao, Xin-Ling Du, Jia-Hong Xia, Nian-Guo Dong, Wei Su, Ni Xia, Xin-Xin Yan, Shao-Fang Nie, Juan Liu, Su-Feng Zhou, Rui Yao, Jiang-Jiao Xie, Harish Jevallee, Xiang Wang, Meng-Yang Liao, Guo-Ping Shi, Michael Fu, Yu-Hua Liao, and Xiang Cheng

Subjects
Medicine, Science
Published
2011
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2. Impaired thymic export and apoptosis contribute to regulatory T-cell defects in patients with chronic heart failure.

Author

Ting-Ting Tang, Zheng-Feng Zhu, Jun Wang, Wen-Cai Zhang, Xin Tu, Hong Xiao, Xin-Ling Du, Jia-Hong Xia, Nian-Guo Dong, Wei Su, Ni Xia, Xin-Xin Yan, Shao-Fang Nie, Juan Liu, Su-Feng Zhou, Rui Yao, Jiang-Jiao Xie, Harish Jevallee, Xiang Wang, Meng-Yang Liao, Guo-Ping Shi, Michael Fu, Yu-Hua Liao, and Xiang Cheng

Subjects
Medicine, Science
Abstract

Animal studies suggest that regulatory T (T(reg)) cells play a beneficial role in ventricular remodeling and our previous data have demonstrated defects of T(reg) cells in patients with chronic heart failure (CHF). However, the mechanisms behind T(reg-)cell defects remained unknown. We here sought to elucidate the mechanism of T(reg-)cell defects in CHF patients.We performed flow cytometry analysis and demonstrated reduced numbers of peripheral blood CD4(+)CD25(+)FOXP3(+)CD45RO(-)CD45RA(+) naïve T(reg) (nT(reg)) cells and CD4(+)CD25(+)FOXP3(+)CD45RO(+)CD45RA(-) memory T(reg) (mT(reg)) cells in CHF patients as compared with non-CHF controls. Moreover, the nT(reg)/mT(reg) ratio (p

Published
2011
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