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Objective: To investigate the diagnostic value of multi-slice spiral computed tomography (MSCT) combined with magnetic resonance imaging (MRI) for early central lung cancer and postoperative recurrence. Methods: 98 patients with early central lung cancer who were treated in our hospital from August 2015 to February 2017 were selected.All patients were examined by MSCT and MRI. The diagnostic results of separate MSCT and MSCT combined with MRI were analyzed and compared.Follow up for 1 year, the diagnosis results of separate MSCT and MSCT combined with MRI in patient with a suspected relapse were observed and compared, and the sensitivity and specificity to the diagnosis of recurrence between them were compared. Results: The accuracy rate, misdiagnosis rate and missed diagnosis rate of MSCT combined with MRI were 94.90%, 1.02% and 4.08% respectively, compared with 82.65%, 9.18% and 8.16%of separate MSCT, the accuracy rate of MSCT combined with MRI diagnosis was increased significantly, and the misdiagnosis rate was decreased significantly (P<0.05), there was no significant difference in missed diagnosis rate between the two diagnostic methods (P>0.05). Follow up for 1 year, 98 patients were reexamined 122 times, and 49 cases recurred. The sensitivity and specificity of MSCT combined with MRI in diagnosis of postoperative recurrence were 97.96% and 93.15%, which were significantly higher than 83.67%and 82.19%of separate MSCT (P<0.05). Conclusion: MSCT combined with MRI has high accuracy rate in the diagnosis of early central lung cancer, and it can improve sensitivity and specificity in diagnosis of postoperative recurrence. [ABSTRACT FROM AUTHOR]