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Objective: To investigate the effect of pingganxifeng decoction combined with magnesium sulfate on hemodynamics, glucose and lipid metabolism and pregnancy outcome in patients with pregnancy induced hypertension (GH) with deficiency of liver and kidney yin. 119 patients with GH who were admitted to Lanzhou Second People's Hospital from March 2018 to October 2019 were selected, and they were randomly divided into control group (n=59) and study group (n=60). The control group was treated with magnesium sulfate. The study group was treated with pingganxifeng decoction on the basis of the control group. The efficacy, hemody)namics, glycolipid metabolism, blood pressure, heart rate and TCM Syndromes scores and pregnancy outcome of the two groups were compared. The total clinical effective rate of the study group was 91.67% (55/60), which was significantly higher than that of the control group 77.97% (46/59) (P<0.05). The systolic pressure, diastolic pressure, mean arterial pressure and heart rate of the two groups decreased at 7 days after treatment, and those in the study group were lower than those in the control group (P<0.05). 7 days after treat)ment, the cardiac output (CO) and cardiac index (CI) of the two groups decreased, and those of the study group were lower than those of the control group (P<0.05). Triglyceride (TG), low-density lipoprotein (LDL-C), fasting glucose, total cholesterol (TC) decreased and high-density lipoprotein (HDL-C) increased in the two groups at 7 days after treatment (P<0.05), and the change degree of the above indexes in the study group was greater than that in the control group (P<0.05). 7 days after treatment, the symptom scores of blurred vision, hot hands and feet, fine pulse, dry mouth and constipation, and little red tongue and moss of the two groups decreased, and those in the study group were lower than those in the control group (P<0.05). The incidence of adverse pregnancy outcome in the study group was lower than that in the control group (P<0.05). Pingganxifeng decoction combined with magnesium sulfate is effective in the treatment of GH with deficiency of liver and kidney yin. It can effectively improve the clinical symptoms, hemodynamics, glucose and lipid metabolism of the patients, and reduce the incidence of adverse pregnancy outcomes, the clinical application value is higher. [ABSTRACT FROM AUTHOR]

To explore the clinical value of color Doppler ultrasound in assessing the degree of hypoxia in pregnancy-induced hypertension. A total of 106 pregnancy-induced hypertensive admitted to our hospital from June 2017 to June 2019 were enrolled in the study group, and 103 normal pregnant women in the same period as the control group, and the two groups were monitored by color Doppler ultrasonography. The uterine artery hemodynamics of the two groups of pregnant women were monitored by color Doppler ultrasonography, and the degree of hypoxia in neonates was analyzed. The RI, PI and S/D levels of the pregnant women in the study group were significantly higher than those in the control group (P<0.05). The early diastolic sinus rate was 47.17 %, which was significantly higher than the control group (8.74 %, P<0.05). The average gestational age, neonatal weight and body mass index of the pregnant women in the study group were significantly lower than those in the control group (P<0.05), and the premature rate was 19.81 %, the cesarean section rate was 64.15 %, and the fetal distress rate was 15.09 %, which was significantly higher than the control group (5.83 %, 19.42 %, and 4.85 %, P<0.05). The gestational age and neonatal weight of the incision group in the study group were significantly lower than those in the non-incision group (P<0.05). The incidence of amniotic fluid abnormality in the study group was 16.00 %, the premature birth rate was 40.00 %, the neonatal asphyxia rate was 14.00 %, and the incidence of fetal distress was 26.00 %, which was significantly higher than the control group (5.36%, 1.79%, 1.79%, 5.38 %, P<0.05). Using color Doppler ultrasound to detect the uterine artery blood flow spectrum of pregnant women can be used as a way to understand the uterus-placenta-fetal circulation, assess the risk of pregnancy complications, and monitor the intrauterine growth and development. [ABSTRACT FROM AUTHOR]

Objective: To investigate the clinical effects and mechanisms of nifedipine combined with magnesiumsulfate on elderly pregnant with hypertension. Methods: A total of 54 elderly pregnant with hypertension of pregnancy fromour hospital were collected and randomly divided into the group A and groupB with 27 cases in each group. Patients in the group A were treated by 5%glucose injection 100 mL and 25%magnesium sulphate injection 20 mL intravenous drip, 30 min infusion; 5%glucose injection500ml added 40 mL 25% magnesium sulfate injection 1~2 g/h, intravenous drip; patients in the group B were treated on the basis of group A with nifedipine release tablets 30 mg oral, 1 time/day, 2 groups of patients were treated for 7 days. After treatment, the blood pressure, CRP, IL-6, TNF-α and proteinuria levels were compared between the two groups. Results: Compared with before treatment, the systolic blood pressure, diastolic blood pressure, CRP, IL-6, TNF-αand proteinuria levels of both groups were significantly decreased after treatment (P<0.05); compared with group A, the systolic blood pressure, diastolic blood pressure, CRP, IL-6, TNF-αand proteinuria levels of group B were obviously lower (P<0.05). Conclusions: Nifedipine combined with magnesium sulfate had better clinical efficacy in the treatment of elderly pregnant women with pregnancy hypertension, which might be relate to the reduce of CRP, IL-6 and TNF-αlevels. [ABSTRACT FROM AUTHOR]