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This study clinically evaluated the efficacy of two different home tooth-whitening protocols to determine which one is more effective by applying the whitening gel every 48 hours or every 72 hours for 6 weeks. The differences in tooth sensitivity were also analyzed. A sample of 72 patients were randomly divided into four groups: In group A (n = 24), 16% carbamide peroxide (Pola Night, SDI Limited) was applied every 48 hours for 6 weeks; in group B (n = 24), 16% carbamide peroxide was applied every 72 hours for 6 weeks; in group C (control; n = 12), a placebo gel without peroxide (glycerin gel) was applied every 48 hours for 6 weeks; and in group D (control; n = 12), a placebo gel without peroxide (glycerin gel) was applied every 72 hours for 6 weeks. To compare the groups, color measurements were made using a spectrophotometer. For statistical analysis, ANOVA with Bonferroni test was used. The confidence interval (CI) was set at 95% (P ≤ .05). No statistically significant differences were found between applying 16% carbamide peroxide every 48 hours and every 72 hours for 6 weeks (P > .05). The study concluded that 16% carbamide peroxide was equally effective when applied using both protocols. [ABSTRACT FROM AUTHOR]

This study aimed to clinically evaluate the effectiveness of two different at-home whitening protocols and to determine which is more effective: applying the whitening gel (16% carbamide peroxide) every 24 hours (Group A) or every 48 hours (Group B) for 2 weeks. Group C received a placebo gel (glycerin) without peroxide, which was applied every 24 hours for 2 weeks. The differences in terms of tooth sensitivity were also analyzed. A sample of 60 patients was divided into three groups of 20 patients. To compare the groups, color measurements were made using a spectrophotometer, and Student t test was used for independent samples. The confidence level was set at 95% (P ≤ .05). No statistically significant differences were found between Groups A and B (P > .05). The study concluded that 16% carbamide peroxide was equally effective when applied with either protocol and obtained the same results, but the 48-hour application protocol produced less sensitivity than the 24-hour application protocol. [ABSTRACT FROM AUTHOR]