9 results on '"Turcan, S"'
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2. Disease course of Ulcerative Colitis during the first ten years following diagnosis in a prospective European population-based inception cohort - the Epi-IBD cohort
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Wewer, M. D., Salupere, R., Kievit, H. A. L., Nielsen, K. R., Midjord, J., Domislovic, V., Krznarić, Ž., Pedersen, N., Jens, K., Eriksson, Carl, Halfvarson, Jonas, Talbot, A., Sebastian, S., Goldis, A., Misra, R., Arebi, N., Ilus, T., Oksanen, P., Neuman, A., Andersen, V., Skamnelos, A., Katsanos, K. H., Negru, I., Turcan, S., Borg, B., Ellul, P., Kupcinskas, J., Kiudelis, G., Yzet, C., Fumery, M., Kaimakliotis, I. P., Lorenzon, G., D'Inca, R., Hernandez, V., Fernandez, A., Langholz, E., Munkholm, P., Burisch, J., Wewer, M. D., Salupere, R., Kievit, H. A. L., Nielsen, K. R., Midjord, J., Domislovic, V., Krznarić, Ž., Pedersen, N., Jens, K., Eriksson, Carl, Halfvarson, Jonas, Talbot, A., Sebastian, S., Goldis, A., Misra, R., Arebi, N., Ilus, T., Oksanen, P., Neuman, A., Andersen, V., Skamnelos, A., Katsanos, K. H., Negru, I., Turcan, S., Borg, B., Ellul, P., Kupcinskas, J., Kiudelis, G., Yzet, C., Fumery, M., Kaimakliotis, I. P., Lorenzon, G., D'Inca, R., Hernandez, V., Fernandez, A., Langholz, E., Munkholm, P., and Burisch, J.
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- 2023
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3. Disease course during the first five years following diagnosis in a prospective European population-based inception cohort - the ECCO-EpiCom cohort
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Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., Munkholm, P., Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., and Munkholm, P.
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- 2017
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4. Disease course during the first five years following diagnosis in a prospective European population-based inception cohort - the ECCO-EpiCom cohort
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Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., Munkholm, P., Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., and Munkholm, P.
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- 2017
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5. Change in Crohn's disease behavior in a prospective European population-based inception cohort - the ECCO-EpiCom cohort
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Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., Munkholm, P., Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., and Munkholm, P.
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- 2017
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6. The risk of proximal disease extension in patients with limited ulcerative colitis in a prospective European population-based inception cohort - the ECCO-EpiCom cohort
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Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., Munkholm, P., Burisch, J., Halfvarson, Jonas, Kupcinskas, L., Hernandez, V., Kaimakliotis, I., Valpiani, D., Pedersen, N., Duricova, D., Kievit, L., Dahlerup, J. F., Fumery, M., Salupere, R., Arebi, N., Nielsen, K. R., Giannotta, M., Oksanen, P., Katsanos, K. H., Vegh, Z., Ellul, P., Schwartz, D., Cukovic-Cavka, S., D'Inca, R., Turcan, S., Magro, F., Goldis, A., Langholz, E., Lakatos, P. L., and Munkholm, P.
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- 2017
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7. East-West gradient in the incidence of inflammatory bowel disease in Europe : the ECCO-EpiCom inception cohort
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Burisch, J., Pedersen, N., Cukovic-Cavka, S., Brinar, M., Kaimakliotis, I., Duricova, D., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Andersen, V., Krabbe, S., Dahlerup, J. F., Salupere, R., Nielsen, K. R., Olsen, J., Manninen, P., Collin, P., Tsianos, E. V., Katsanos, K. H., Ladefoged, K., Lakatos, L., Bjornsson, E., Ragnarsson, G., Bailey, Y., Odes, S., Schwartz, D., Martinato, M., Lupinacci, G., Milla, M., De Padova, A., D'lnca, R., Beltrami, M., Kupcinskas, L., Kiudelis, G., Turcan, S., Tighineanu, O., Mihu, I., Magro, F., Barros, L. F., Goldis, A., Lazar, D., Belousova, E., Nikulina, I., Hernandez, V., Martinez-Ares, D., Almer, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Sebastian, S., Lakatos, P. L., Langholz, E., Munkholm, P., Burisch, J., Pedersen, N., Cukovic-Cavka, S., Brinar, M., Kaimakliotis, I., Duricova, D., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Andersen, V., Krabbe, S., Dahlerup, J. F., Salupere, R., Nielsen, K. R., Olsen, J., Manninen, P., Collin, P., Tsianos, E. V., Katsanos, K. H., Ladefoged, K., Lakatos, L., Bjornsson, E., Ragnarsson, G., Bailey, Y., Odes, S., Schwartz, D., Martinato, M., Lupinacci, G., Milla, M., De Padova, A., D'lnca, R., Beltrami, M., Kupcinskas, L., Kiudelis, G., Turcan, S., Tighineanu, O., Mihu, I., Magro, F., Barros, L. F., Goldis, A., Lazar, D., Belousova, E., Nikulina, I., Hernandez, V., Martinez-Ares, D., Almer, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Sebastian, S., Lakatos, P. L., Langholz, E., and Munkholm, P.
- Abstract
Objective: The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe. The reasons for these changes remain unknown. The aim of this study was to investigate whether an East–West gradient in the incidence of IBD in Europe exists. Design: A prospective, uniformly diagnosed, population based inception cohort of IBD patients in 31 centres from 14 Western and eight Eastern European countries covering a total background population of approximately 10.1 million people was created. One-third of the centres had previous experience with inception cohorts. Patients were entered into a low cost, web based epidemiological database, making participation possible regardless of socioeconomic status and prior experience. Results: 1515 patients aged 15 years or older were included, of whom 535 (35%) were diagnosed with Crohn’s disease (CD), 813 (54%) with ulcerative colitis (UC) and 167 (11%) with IBD unclassified (IBDU). The overall incidence rate ratios in all Western European centres were 1.9 (95% CI 1.5 to 2.4) for CD and 2.1 (95% CI 1.8 to 2.6) for UC compared with Eastern European centres. The median crude annual incidence rates per 100 000 in 2010 for CD were 6.5 (range 0–10.7) in Western European centres and 3.1 (range 0.4–11.5) in Eastern European centres, for UC 10.8 (range 2.9–31.5) and 4.1 (range 2.4–10.3), respectively, and for IBDU 1.9 (range 0–39.4) and 0 (range 0–1.2), respectively. In Western Europe, 92% of CD, 78% of UC and 74% of IBDU patients had a colonoscopy performed as the diagnostic procedure compared with 90%, 100% and 96%, respectively, in Eastern Europe. 8% of CD and 1% of UC patients in both regions underwent surgery within the first 3 months of the onset of disease. 7% of CD patients and 3% of UC patients from Western Europe received biological treatment as rescue therapy. Of all European CD patients, 20% received only 5-aminosalicylates as induction therapy. Conclusions: An East–West gradient in IBD incidence exists in Europe. Am
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- 2014
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8. Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe : An ECCO-EpiCom study
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Burisch, J., Pedersen, N., Cukovic-Cavka, S., Turk, N., Kaimakliotis, I., Duricova, D., Bortlik, M., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Krabbe, S., Andersen, V., Dahlerup, J. F., Kjeldsen, J., Salupere, R., Olsen, J., Nielsen, K. R., Manninen, P., Collin, P., Katsanos, K. H., Tsianos, E. V., Ladefoged, K., Lakatos, L., Ragnarsson, G., Björnsson, E., Bailey, Y., O'Morain, C., Schwartz, D., Odes, S., Giannotta, M., Girardin, G., Kiudelis, G., Kupcinskas, L., Turcan, S., Barros, L., Magro, F., Lazar, D., Goldis, A., Nikulina, I., Belousova, E., Martinez-Ares, D., Hernandez, V., Almer, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Tsai, H. H., Sebastian, S., Lakatos, P. L., Langholz, E., Munkholm, P., Burisch, J., Pedersen, N., Cukovic-Cavka, S., Turk, N., Kaimakliotis, I., Duricova, D., Bortlik, M., Shonova, O., Vind, I., Avnstrom, S., Thorsgaard, N., Krabbe, S., Andersen, V., Dahlerup, J. F., Kjeldsen, J., Salupere, R., Olsen, J., Nielsen, K. R., Manninen, P., Collin, P., Katsanos, K. H., Tsianos, E. V., Ladefoged, K., Lakatos, L., Ragnarsson, G., Björnsson, E., Bailey, Y., O'Morain, C., Schwartz, D., Odes, S., Giannotta, M., Girardin, G., Kiudelis, G., Kupcinskas, L., Turcan, S., Barros, L., Magro, F., Lazar, D., Goldis, A., Nikulina, I., Belousova, E., Martinez-Ares, D., Hernandez, V., Almer, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Tsai, H. H., Sebastian, S., Lakatos, P. L., Langholz, E., and Munkholm, P.
- Abstract
Background and Aims: The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more "westernised" standard of Living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1 million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p < 0.01). Daily consumption of fast food as well as appendectomy before the age of 20 was more frequent in Eastern European than in Western European UC patients (p < 0.01). Eastern European CD and UC patients had received more vaccinations and experienced fewer childhood infections than Western European patients (p < 0.01). Conclusions: In this European population-based inception cohort of unselected IBD patients, Eastern and Western European patients differed in environmental factors prior to diagnosis. Eastern European patients exhibited higher occurrences of suspected risk factors for IBD included in the Western lifestyle. (C) 2013 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved., Funding Agencies:Danish Colitis Crohn Patients Organisation (CCF)Vibeke Binder and Povl Riis FoundationScientific Council at Herlev HospitalSigrid Rignnor Moran Foundation, Aage and Johanne Louis-Hansens FoundationMunkholm FoundationC.C. Klestrup and Henriette Klestrup FoundationKnud and Dagny Gad Andresens FoundationElse and Mogens Wedell-Wedellsborgs FoundationDirektor Jacob Madsen and Olga Madsen's Foundation, Scan Vet
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- 2014
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9. Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with Inflammatory Bowel Disease : An ECCO-EpiCom study
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Burisch, J., Weimers, P., Pedersen, N., Cukovic-Cavka, S., Vucelic, B., Kaimakliotis, I., Duricova, D., Bortlik, M., Shonová, O., Vind, I., Avnstrøm, S., Thorsgaard, N., Krabbe, S., Andersen, V., Dahlerup, J. F., Kjeldsen, J., Salupere, R., Olsen, J., Nielsen, K. R., Manninen, P., Collin, P., Katsanos, K. H., Tsianos, E. V., Ladefoged, K., Lakatos, L., Ragnarsson, G., Björnsson, E., Bailey, Y., O'Morain, C., Schwartz, D., Odes, S., Valpiani, D., Boni, M. C., Jonaitis, L., Kupcinskas, L., Turcan, S., Barros, L., Magro, F., Lazar, D., Goldis, A., Nikulina, I., Belousova, E., Fernandez, A., Sanroman, L., Almér, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Diggory, T., Sebastian, S., Lakatos, P. L., Langholz, E., Munkholm, P., Burisch, J., Weimers, P., Pedersen, N., Cukovic-Cavka, S., Vucelic, B., Kaimakliotis, I., Duricova, D., Bortlik, M., Shonová, O., Vind, I., Avnstrøm, S., Thorsgaard, N., Krabbe, S., Andersen, V., Dahlerup, J. F., Kjeldsen, J., Salupere, R., Olsen, J., Nielsen, K. R., Manninen, P., Collin, P., Katsanos, K. H., Tsianos, E. V., Ladefoged, K., Lakatos, L., Ragnarsson, G., Björnsson, E., Bailey, Y., O'Morain, C., Schwartz, D., Odes, S., Valpiani, D., Boni, M. C., Jonaitis, L., Kupcinskas, L., Turcan, S., Barros, L., Magro, F., Lazar, D., Goldis, A., Nikulina, I., Belousova, E., Fernandez, A., Sanroman, L., Almér, S., Zhulina, Yaroslava, Halfvarson, Jonas, Arebi, N., Diggory, T., Sebastian, S., Lakatos, P. L., Langholz, E., and Munkholm, P.
- Abstract
Background & Aims: Health-related quality of life (HRQoL) is impaired in patients with Inflammatory Bowel Disease (IBD). The aim was prospectively to assess and validate the pattern of HRQoL in an unselected, population-based inception cohort of IBD patients from Eastern and Western Europe. Methods: The EpiCom inception cohort consists of 1560 IBD patients from 31 European centres covering a background population of approximately 10.1 million. Patients answered the disease specific Short Inflammatory Bowel Disease Questionnaire (SIBDQ) and generic Short Form 12 (SF-12) questionnaire at diagnosis and after one year of follow-up. Results: In total, 1079 patients were included in this study. Crohn's disease (CD) patients mean SIBDQ scores improved from 45.3 to 55.3 in Eastern Europe and from 44.9 to 53.6 in Western Europe. SIBDQ scores for ulcerative colitis (UC) patients improved from 44.9 to 57.4 and from 48.8 to 55.7, respectively. UC patients needing surgery or biologicals had lower SIBDQ scores before and after compared to the rest, while biological therapy improved SIBDQ scores in CD. CD and UC patients in both regions improved all SF-12 scores. Only Eastern European UC patients achieved SF-12 summary scores equal to or above the normal population. Conclusion: Medical and surgical treatment improved HRQoL during the first year of disease. The majority of IBD patients in both Eastern and Western Europe reported a positive perception of disease-specific but not generic HRQoL. Biological therapy improved HRQoL in CD patients, while UC patients in need of surgery or biological therapy experienced lower perceptions of HRQoL than the rest., Munkholm, P. On behalf of the EpiCom-groupValpiani D., Boni M. C. On behalf of the EpiCom Northern Italy centre based in Crema and oCremona, Firenze, Forlì, Padova and Reggio Emilia, Italy Funding Agencies:Danish Colitis Crohn Patients Organization (CCF)Vibeke Binder and Povl Riis FoundationScientific Council at Herlev HospitalSigrid Rigmor Moran FoundationAage and Johanne Louis-Hansens FoundationMunkholm FoundationC.C. Klestrup and Henriette Klestrup FoundationKnud and Dagny Gad Andresens FoundationElse and Mogens Wedell-Wedellsborgs FoundationDirektor Jacob Madsen and Olga Madsens FoundationScanVetTorben og Alice Frimodt FoundationLaegernes forsikringsforening af 1891Bengt Ihre's foundation, Nanna Svartz' foundationÖrebro University Hospital Research FoundationÖrebro County Research FoundationSwedish Foundation for Gastrointestinal researchSwedish Research CouncilSwedish Society of MedicineResearch Council of South-East SwedenCounty Council of ÖstergötlandSwedish Organization for the study of inflammatory bowel diseaseCompetitive State Research Financing of the Expert Responsibility Area of Tampere University HospitalEuropean Crohn's and Colitis Organization
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- 2014
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