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Background: The problem of inappropriate deployment of medical equipment in hospitals is a significant issue in China. The purpose of the information system for rational deployment of medical equipment (MERDIS) is to inform judgements about the efficient and rational deployment of medical equipment in hospitals. For research needs, the basic information of 52 hospitals in Shanghai and other provinces are investigated. The deployment method based on clinical pathway and deployment method based on big data are designed to support the data analysis of the system. Through the analysis of macro data, the rational deployment plan of medical equipment in a certain hospital is given. Result: Through the MERDIS system, it is convenient, accurate and intuitive to get the rational deployment plan and suggestions of different types of hospitals affected by different factors can be given conveniently, accurately and intuitively.Conclusion: The design of the MERDIS system provides the development basis for the subsequent development of medical equipment macro data management. In the process of continuous improvement and supplement of data, the software model will become more and more accurate and reliable.