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Introduction: Urinary stone disease (USD) prevalence is highly variable worldwide, from 2.5 to 20%. This research aims to describe the prevalence and characteristics of USD in an urban population in Chile. Methods: retrospective descriptive research based on abdominal computed tomography (CT) registries done at our hospital, between 2019 and 2020. We selected people 15 years old and older. Sample size was calculated and patients were randomly selected. Our primary outcome is to describe the characteristics of kidney stones (KS) in this population. Secondary outcomes are the prevalence of ureterolithiasis and cystolithiasis. Results: 1,001 CT were randomly reviewed. Kidney stones were detected in 144 patients, 75 females (52.1%) and 69 males (47.9%). The estimated prevalence of nephrolithiasis was 14.4% (95%CI 12.3 - 16.7); among women was 12.7% (95%CI 10.2 - 15.8) compared to 16.7% (95%CI 13.2 - 20.6) in men. The mean age was 56.6 years old (SD 15.5). The mean number of KS per patient was 2.5, the mode was 1 KS per patient. The mean radiodensity of KS was 501 HU (SD 345.9). The mean largest diameter was 10.9 mm (SD 16.8), and the mean volume was 154.0 mm3 (SD 1,544.1). Related to KS size, 101 cases (70.1%) were 10 mm or less, 18 (12.5%) between 11 to 20 mm and 25 (17.4%) larger than 20mm. Ureterolithiasis was present in 33 cases (3.3%) and cystolithiasis in 5 patients (0.5%). Conclusions: KS is a prevalent disease in our population, more frequent in men than women and affecting working-age people.