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Your search keyword '"Barlow, Jillian L."' showing total 5 results
Start Over Author "Barlow, Jillian L." Publisher rockefeller university press
5 results on '"Barlow, Jillian L."'

1. Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation

Author

Chen, Yi-Ling, primary, Gomes, Tomas, additional, Hardman, Clare S., additional, Vieira Braga, Felipe A., additional, Gutowska-Owsiak, Danuta, additional, Salimi, Maryam, additional, Gray, Nicki, additional, Duncan, David A., additional, Reynolds, Gary, additional, Johnson, David, additional, Salio, Mariolina, additional, Cerundolo, Vincenzo, additional, Barlow, Jillian L., additional, McKenzie, Andrew N.J., additional, Teichmann, Sarah A., additional, Haniffa, Muzlifah, additional, and Ogg, Graham, additional

Published
2019
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2. A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue

Author

Rana, Batika M.J., primary, Jou, Eric, additional, Barlow, Jillian L., additional, Rodriguez-Rodriguez, Noe, additional, Walker, Jennifer A., additional, Knox, Claire, additional, Jolin, Helen E., additional, Hardman, Clare S., additional, Sivasubramaniam, Meera, additional, Szeto, Aydan, additional, Cohen, E. Suzanne, additional, Scott, Ian C., additional, Sleeman, Matthew A., additional, Chidomere, Chiamaka I., additional, Cruz Migoni, Sara, additional, Caamano, Jorge, additional, Jorgensen, Helle F., additional, Carobbio, Stefania, additional, Vidal-Puig, Antonio, additional, and McKenzie, Andrew N.J., additional

Published
2019
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3. A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

Author

Salimi, Maryam, primary, Barlow, Jillian L., additional, Saunders, Sean P., additional, Xue, Luzheng, additional, Gutowska-Owsiak, Danuta, additional, Wang, Xinwen, additional, Huang, Li-Chieh, additional, Johnson, David, additional, Scanlon, Seth T., additional, McKenzie, Andrew N.J., additional, Fallon, Padraic G., additional, and Ogg, Graham S., additional

Published
2013
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5. Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation.

Author

Chen YL, Gomes T, Hardman CS, Vieira Braga FA, Gutowska-Owsiak D, Salimi M, Gray N, Duncan DA, Reynolds G, Johnson D, Salio M, Cerundolo V, Barlow JL, McKenzie ANJ, Teichmann SA, Haniffa M, and Ogg G

Subjects
Antigen Presentation physiology, Antigens, CD1 metabolism, Humans, Interleukin-3 Receptor alpha Subunit metabolism, Lymph Nodes metabolism, Dendritic Cells metabolism, Inflammation metabolism, Lectins, C-Type metabolism, Membrane Glycoproteins metabolism, Receptors, Immunologic metabolism, Skin metabolism
Abstract

Plasmacytoid dendritic cells (pDCs) produce type I interferon (IFN-I) and are traditionally defined as being BDCA-2+CD123+. pDCs are not readily detectable in healthy human skin, but have been suggested to accumulate in wounds. Here, we describe a CD1a-bearing BDCA-2+CD123int DC subset that rapidly infiltrates human skin wounds and comprises a major DC population. Using single-cell RNA sequencing, we show that these cells are largely activated DCs acquiring features compatible with lymph node homing and antigen presentation, but unexpectedly express both BDCA-2 and CD123, potentially mimicking pDCs. Furthermore, a third BDCA-2-expressing population, Axl+Siglec-6+ DCs (ASDC), was also found to infiltrate human skin during wounding. These data demonstrate early skin infiltration of a previously unrecognized CD123intBDCA-2+CD1a+ DC subset during acute sterile inflammation, and prompt a re-evaluation of previously ascribed pDC involvement in skin disease., (© 2019 Chen et al.)

Published
2020
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