1. [The levels of DNA repair in the cells of diploid and tetraploid cell cultures].
- Author
-
Kudriavtsev BN, Aprelikova ON, Ni VV, Semenova EG, and Sukhikh TR
- Subjects
- Animals, Autoradiography, Cell Line, Transformed, Cells, Cultured cytology, Cells, Cultured metabolism, DNA, Neoplasm analysis, DNA, Neoplasm drug effects, Flow Cytometry, Liver cytology, Liver metabolism, N-Glycosyl Hydrolases metabolism, N-Glycosyl Hydrolases radiation effects, Rats, Sarcoma, Avian chemistry, Sarcoma, Avian metabolism, Shrews, Tumor Cells, Cultured chemistry, Tumor Cells, Cultured metabolism, Tumor Cells, Cultured radiation effects, Ultraviolet Rays, Uracil-DNA Glycosidase, DNA Glycosylases, DNA Repair radiation effects, DNA, Neoplasm biosynthesis, Diploidy, Polyploidy
- Abstract
Levels of unscheduled DNA synthesis after UV-irradiation were investigated in addition to the activities of DNA-repair enzyme uracil-DNA glycosilase in cells of both diploid (XC-D) and tetraploid (XC-T) cell cultures. It was shown that repair levels were increasing directly and proportionally to the cell ploidy.
- Published
- 1991