1. Decarboxylative C–H silylation of N-heteroarenes with silanecarboxylic acids.
- Author
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Zhang, Guodong, Tian, Ye, Zhang, Chengyu, Li, Xiang, and Chen, Feng
- Subjects
- *
CARBOXYLIC acids , *SILYLATION , *ACIDS , *DECARBOXYLATION - Abstract
Established decarboxylative Minisci reactions are limited to aliphatic carboxylic acids, as their analogs, silanecarboxylic acids, have been rarely investigated. Herein, we present a new decarboxylative Minisci-type reaction of N-heteroarenes with silanecarboxylic acids under photo- or silver-mediated conditions. This C–H silylation strategy provides efficient access to diverse N-heteroarylsilanes in moderate to excellent yields with high regioselectivity, among which Ag-catalysed decarboxylation of silanecarboxylic acids furnishes an unprecedented method for silyl radical generation. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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