1. Biocompatibility and photo-induced antibacterial activity of lignin-stabilized noble metal nanoparticles
- Author
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Juan C. Scaiano, Diamela María Rocca, Anabel E. Lanterna, Julie P. Vanegas, M. Cecilia Becerra, and Kelsey Fournier
- Subjects
Biocompatibility ,General Chemical Engineering ,NOBLE NANOPARTICLES ,Nanoparticle ,macromolecular substances ,02 engineering and technology ,engineering.material ,010402 general chemistry ,complex mixtures ,01 natural sciences ,Silver nanoparticle ,BIOCOMPATIBILITY ,Metal ,purl.org/becyt/ford/1 [https] ,ANTIBACTERIAL ,purl.org/becyt/ford/1.4 [https] ,Chemistry ,Otras Ciencias Químicas ,technology, industry, and agriculture ,Ciencias Químicas ,food and beverages ,General Chemistry ,021001 nanoscience & nanotechnology ,Antimicrobial ,0104 chemical sciences ,Colloidal gold ,visual_art ,visual_art.visual_art_medium ,engineering ,Noble metal ,0210 nano-technology ,Antibacterial activity ,CIENCIAS NATURALES Y EXACTAS ,Nuclear chemistry ,LIGNIN - Abstract
One-pot thermal and photochemical syntheses of lignin-doped silver and gold nanoparticles were developed and their antimicrobial properties were studied against Escherichia coli and Staphylococcus aureus. The nature of the lignin as well as the metal are directly involved in the antimicrobial activity observed in these nanocomposites. Whereas one of the nanocomposites is innocuous under dark conditions and shows photoinduced activity only against Staphylococcus aureus, the rest of the lignin-coated silver nanoparticles studied show antimicrobial activity under dark and light conditions for both bacteria strains. Additionally, only photoinduced activity is observed for lignin-coated gold nanoparticles. Importantly, the particles are non-cytotoxic towards human cells at the bactericidal concentrations. Preliminary assays show these silver nanoparticles as potential antimicrobial agents towards S. aureus biofilm eradication. Fil: Rocca, Diamela María. University Of Ottawa. Faculty Of Science; Canadá. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Farmacia; Argentina Fil: Vanegas, Julie P.. University Of Ottawa. Faculty Of Science; Canadá Fil: Fournier, Kelsey. University Of Ottawa. Faculty Of Science; Canadá Fil: Becerra, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina Fil: Scaiano, Juan Cesar. University Of Ottawa. Faculty Of Science; Canadá Fil: Lanterna, Anabel Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
- Published
- 2018