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Start Over Author "Minhuan Lan" Publisher royal society of chemistry
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1. Copper coordination-based conjugated polymer nanoparticles for synergistic photodynamic and chemodynamic therapy.

Author

Qiang Cheng, Yuyan Li, Wei Huang, Ke Li, Minhuan Lan, Benhua Wang, Jianxiu Wang, and Xiangzhi Song

Subjects
PHOTODYNAMIC therapy, CONJUGATED polymers, REACTIVE oxygen species, COPPER, NANOPARTICLES
Abstract

In this work, we presented a copper coordination-based conjugated polymer nanoparticle (PPE-Cu NPs) for synergistic PDT/CDT. Upon irradiation, PPE-Cu NPs exhibited good singlet oxygen generation capability (ΦΔ = 0.33). Meanwhile, PPE-Cu NPs were able to generate ˙OH in the presence of GSH and H2O2. Cellular experiments demonstrated that PPE-Cu NPs can serve as effective agents for synergistic PDT/CDT therapy. [ABSTRACT FROM AUTHOR]

Published
2023
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