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Your search keyword '"Zhong, Yan‐Mei"' showing total 2 results
Start Over Author "Zhong, Yan‐Mei" Publisher royal society of chemistry
2 results on '"Zhong, Yan‐Mei"'

2. Quantitative tracking of endoplasmic reticulum viscosity during ferroptosis by an iridium complex via TPPLM.

Author

Hao, Liang, Zhong, Yan-Mei, Tan, Cai-Ping, and Mao, Zong-Wan

Subjects
*ENDOPLASMIC reticulum, *IRIDIUM, *VISCOSITY, *ORGANELLES, *CELL death, *BENZALDEHYDE
Abstract

Herein, we report a neutral iridium complex, [Ir(4-(2-pyridinyl)benzaldehyde)2(acetylacetone)] (Ir-ER), with viscosity-responsive phosphorescent emission intensity and lifetime. Quantitative measurement by two-photon phosphorescent lifetime imaging shows that the viscosity of ER increases significantly in the process of erastin-induced ferroptosis. Our work provides an effective strategy for quantitative measurement of the micro-environmental alternations of subcellular organelles during a specific cell death process. [ABSTRACT FROM AUTHOR]

Published
2021
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