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Your search keyword '"Alessia Ciogli"' showing total 2 results
Start Over Author "Alessia Ciogli" Publisher royal society of chemistry (rsc)
2 results on '"Alessia Ciogli"'

1. Synthesis of 3-substituted 2,3-dihydropyrazino[1,2-a]indol-4(1H)-ones by sequential reactions of 2-indolylmethyl acetates with α-amino acids

Author

Antonella Goggiamani, Antonio Arcadi, Alessia Ciogli, Martina De Angelis, Stefano Dessalvi, Giancarlo Fabrizi, Federica Iavarone, Antonia Iazzetti, Alessio Sferrazza, and Roberta Zoppoli

Subjects
Sequential Reactions. Annulation Reactions. Indole-2-ylmethylacetates. 2, Sequential Reactions. Annulation Reactions. Indole-2-ylmethylacetates. 2,3-Dihydropyrazino[1,2-a]indol-4(1H)-ones, General Chemical Engineering, General Chemistry, 2-a]indol-4(1H)-ones, 3-Dihydropyrazino[1
Abstract

The synthesis of 2,3-dihydropyrazino[1,2-a]indol-4(1H)-ones through the in situ generation of 2-methide-2H-indole intermediate I starting from 2-indolylmethyl acetates under basic conditions/nucleophilic Michael addition/cyclization cascade reaction.

Published
2023
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2. Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality

Author

Luca Prati, Michele Mancinelli, Alessia Ciogli, Andrea Mazzanti, Prati, L., Mancinelli, M., Ciogli, A., and Mazzanti, A.

Subjects
Atropisomer, absolute configurations, D-NMR, 010405 organic chemistry, Phencyclone, Stereochemistry, atropisomers, D-HPLC, D-NMR, Organic Chemistry, Enantioselective synthesis, chemistry.chemical_element, 010402 general chemistry, D-HPLC, 01 natural sciences, Biochemistry, 0104 chemical sciences, Ruthenium, Catalysis, Enantiopure drug, chemistry, Axial chirality, Computational chemistry, Physical and Theoretical Chemistry
Abstract

A series of thermally stable atropisomeric phencyclone ligands (ΔG‡rac > 35 kcal mol-1), bearing two chiral axes, has been successfully synthesized, taking into account the results of DFT calculations on model systems. The absolute configurations of the novel atropisomers have been assigned using TD-DFT simulation of ECD spectra. Atropisomeric phencyclones herein presented pave the way towards new ruthenium-based enantioselective hydrogenation catalysts.

Published
2017
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