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Start Over Descriptor "Inotilone" Publisher royal society of chemistry (rsc)
1 results on '"Inotilone"'

1. Inotilone and related phenylpropanoid polyketides from Inonotus sp. and their identification as potent COX and XO inhibitors

Author

Albert Härtl, Christian Hertweck, Hilaire V. Kemami Wangun, and Trinh Tam Kiet

Subjects
Xanthine Oxidase, Stereochemistry, Inotilone, Biochemistry, chemistry.chemical_compound, Xanthone, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Physical and Theoretical Chemistry, Furans, Oxidase test, Mushroom, Phenylpropionates, biology, Inonotus, Phenylpropanoid, Basidiomycota, Spectrum Analysis, Organic Chemistry, food and beverages, Chromatography, Ion Exchange, biology.organism_classification, chemistry, biology.protein, Macrolides, Cyclooxygenase
Abstract

By bioassay-guided isolation, phenylpropanoid-derived polyketides, including an unusual 5-methyl-3(2H)-furanone derivative (inotilone) with potent cyclooxygenase (COX) and xanthone oxidase (XO) inhibitory activities were obtained from the fruiting body of the mushroom Inonotus sp.

Published
2006
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