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Your search keyword '"Jörg Eschweiler"' showing total 12 results
Start Over Author "Jörg Eschweiler" Publisher rwth aachen university
12 results on '"Jörg Eschweiler"'

1. No difference between mobile and fixed bearing in primary total knee arthroplasty : a meta-analysis

Author

Filippo Migliorini, Nicola Maffulli, Francesco Cuozzo, Marco Pilone, Karen Elsner, and Jörg Eschweiler

Subjects
Treatment Outcome, Knee Joint, Humans, Pain, Orthopedics and Sports Medicine, Surgery, Osteoarthritis, Knee, Range of Motion, Articular, ddc:796, Arthroplasty, Replacement, Knee, Knee Prosthesis
Abstract

Knee surgery, sports traumatology, arthroscopy (2022). doi:10.1007/s00167-022-07065-5, Published by Springer, Berlin ; Heidelberg

Published
2022
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2. L4/5 accessibility for extreme lateral interbody fusion (XLIF): a radiological study

Author

Valentin Quack, Jörg Eschweiler, Christina Prechtel, Filippo Migliorini, Marcel Betsch, Nicola Maffulli, Natalia Gutteck, Markus Tingart, Philipp Kobbe, Miguel Pishnamaz, Frank Hildebrand, and Dariusch Arbab

Subjects
Male, Radiography, Spinal Fusion, Lumbar Vertebrae, Humans, Female, Orthopedics and Sports Medicine, Surgery, Retrospective Studies, Psoas Muscles
Abstract

Journal of orthopaedic surgery and research 17, 483 (2022). doi:10.1186/s13018-022-03320-0, Published by Biomed Central, London

Published
2022
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3. Functionalised High-Performance Oxide Ceramics with Bone Morphogenic Protein 2 (BMP-2) Induced Ossification: An In Vivo Study

Author

Filippo Migliorini, Jörg Eschweiler, Nicola Maffulli, Frank Hildebrand, and Hanno Schenker

Subjects
Space and Planetary Science, Paleontology, General Biochemistry, Genetics and Molecular Biology, Ecology, Evolution, Behavior and Systematics, high-performance oxide ceramics, alumina oxide, BMP-2, implantology, ossification
Abstract

Life : open access journal 12(6), 866 (2022). doi:10.3390/life12060866 special issue: "Special Issue "Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application" / Special Issue Editors: Dr. Filippo Migliorini, Dr. Jörg Eschweiler", Published by MDPI, Basel

Published
2022
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4. The Effect of Breast Size on Spinal Posture

Author

Roman Michalik, Britta Kühlmann, Michael Wild, Hannah Lena Siebers, Filippo Migliorini, Jörg Eschweiler, and Marcel Betsch

Subjects
Surgery, ddc:610
Abstract

Aesthetic plastic surgery (2022). doi:10.1007/s00266-022-03141-w, Published by Springer, New York, NY ; Heidelberg ; Berlin

Published
2022
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5. Prognostic factors for the management of chondral defects of the knee and ankle joint : a systematic review

Author

Filippo Migliorini, Nicola Maffulli, Jörg Eschweiler, Christian Götze, Frank Hildebrand, and Marcel Betsch

Subjects
Emergency Medicine, Orthopedics and Sports Medicine, Surgery, Critical Care and Intensive Care Medicine
Abstract

European journal of trauma and emergency surgery (2022). doi:10.1007/s00068-022-02155-y, Published by Springer Medizin, Heidelberg

Published
2022
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6. No evidence in support of arthroscopic partial meniscectomy in adults with degenerative and nonobstructive meniscal symptoms : a level I evidence-based systematic review

Author

Filippo Migliorini, Francesco Oliva, Jörg Eschweiler, Francesco Cuozzo, Frank Hildebrand, and Nicola Maffulli

Subjects
Orthopedics and Sports Medicine, Surgery, ddc:796
Abstract

Knee surgery, sports traumatology, arthroscopy (2022). doi:10.1007/s00167-022-07040-0, Published by Springer, Heidelberg

Published
2022
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7. Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty

Author

Jörg Eschweiler, Maximilian Praster, Valentin Quack, Jianzhang Li, Björn Rath, Frank Hildebrand, and Filippo Migliorini

Subjects
musculoskeletal diseases, Space and Planetary Science, Paleontology, modeling, total wrist arthroplasty, biomechanics, TWA, General Biochemistry, Genetics and Molecular Biology, Ecology, Evolution, Behavior and Systematics
Abstract

Life : open access journal 12(4), 527 (2022). doi:10.3390/life12040527 special issue: "Special Issue "Advances in Wrist Arthroplasty: From Biomechanics to Clinical Application" / Special Issue Editors: Dr. Filippo Migliorini, Guest Editor; Dr. Jörg Eschweiler, Guest Editor", Published by MDPI, Basel

Published
2022
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8. The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN

Author

Susanne Isfort, Vera Kathrin Preußger, Ralf Weiskirchen, Walter Becker, Tim H. Brümmendorf, Kim Kricheldorf, Marlena Bütow, Stefan Tillmann, Mirle Schemionek, Blanka Kubešová, Nicolas Chatain, Jörg Eschweiler, Steffen Koschmieder, Martina Wessiepe, Barbora Weinbergerova, Jiri Mayer, Kathrin Olschok, Sarah K. Schröder, Milena Kalmer, Julian Baumeister, and Zdenek Racil

Subjects
Cancer Research, Thapsigargin, MPN, UPR, IRE1, Article, Proinflammatory cytokine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, hemic and lymphatic diseases, NGAL, JAK2V617F, BCR-ABL, RC254-282, 030304 developmental biology, 0303 health sciences, Lipocalin 2 (LCN2), Chemistry, Kinase, Binding protein, Endoplasmic reticulum, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Myeloid leukemia, Molecular biology, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Unfolded protein response, ER stress
Abstract

Lipocalin 2 (LCN2), a proinflammatory mediator, is involved in the pathogenesis of myeloproliferative neoplasms (MPN). Here, we investigated the molecular mechanisms of LCN2 overexpression in MPN. LCN2 mRNA expression was 20-fold upregulated in peripheral blood (PB) mononuclear cells of chronic myeloid leukemia (CML) and myelofibrosis (MF) patients vs. healthy controls. In addition, LCN2 serum levels were significantly increased in polycythemia vera (PV) and MF and positively correlated with JAK2V617F and mutated CALR allele burden and neutrophil counts. Mechanistically, we identified endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) as a main driver of LCN2 expression in BCR-ABL- and JAK2V617F-positive 32D cells. The UPR inducer thapsigargin increased LCN2 expression &gt, 100-fold, and this was not affected by kinase inhibition of BCR-ABL or JAK2V617F. Interestingly, inhibition of the UPR regulators inositol-requiring enzyme 1 (IRE1) and c-Jun N-terminal kinase (JNK) significantly reduced thapsigargin-induced LCN2 RNA and protein expression, and luciferase promoter assays identified nuclear factor kappa B (NF-κB) and CCAAT binding protein (C/EBP) as critical regulators of mLCN2 transcription. In conclusion, the IRE1–JNK-NF-κB–C/EBP axis is a major driver of LCN2 expression in MPN, and targeting UPR and LCN2 may represent a promising novel therapeutic approach in MPN.

Published
2021
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9. Detection of Typical Compensatory Movements during Autonomously Performed Exercises Preventing Low Back Pain (LBP)

Author

Asaad Sellmann, Désirée Wagner, Lucas Holtz, Jörg Eschweiler, Christian Diers, Sybele Williams, and Catherine Disselhorst-Klug

Subjects
Chemical technology, Movement, motion analysis, wearable sensors, feature extraction, pattern recognition, TP1-1185, Biochemistry, Article, biomechanics, Atomic and Molecular Physics, and Optics, Exercise Therapy, rehabilitation, Analytical Chemistry, low back pain, accelerometer, Humans, Electrical and Electronic Engineering, Low Back Pain, Instrumentation, Algorithms
Abstract

Sensors 22(1), 111 (2021). doi:10.3390/s22010111 special issue: "Special Issue "Wearable Sensors for Human Movement Analysis Related to Biomechanics and Exercise Physiology" / Special Issue Editor: Prof. Dr. Wolfgang Potthast, Guest Editor", Published by MDPI, Basel

Published
2021
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10. Comparison of different symmetry indices for the quantification of dynamic joint angles

Author

Marcel Betsch, Hannah Lena Siebers, Filippo Migliorini, Waleed Alrawashdeh, Frank Hildebrand, and Jörg Eschweiler

Subjects
medicine.medical_specialty, media_common.quotation_subject, Physical Therapy, Sports Therapy and Rehabilitation, Asymmetry, Gait (human), Physical medicine and rehabilitation, Stairs, medicine, Orthopedics and Sports Medicine, Gait symmetry, media_common, business.industry, Research, Stair climbing, Rehabilitation, IMU, medicine.anatomical_structure, Gait analysis, Sports medicine, Ankle, Symmetry (geometry), business, human activities, RC1200-1245, Sign (mathematics)
Abstract

BMC sports science, medicine & rehabilitation 13(1), 130 (2021). doi:10.1186/s13102-021-00355-4, Published by BioMed Central, London

Published
2021
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11. Evaluation and validation of 2D biomechanical models of the knee for radiograph-based preoperative planning in total knee arthroplasty

Author

Philipp Damm, Klaus Radermacher, Malte Asseln, Jörg Eschweiler, and Adam Trepczynski

Subjects
Male, Knee Joint, Medical Implants, Total Knee Arthroplasty, Physiology, Computer science, Knees, medicine.medical_treatment, Total knee arthroplasty, Knee Joints, 02 engineering and technology, Patient Care Planning, Weight-Bearing, 0302 clinical medicine, Skeletal Joints, Medicine and Health Sciences, Telemetry, Arthroplasty, Replacement, Knee, Musculoskeletal System, 030222 orthopedics, Multidisciplinary, Biomechanics, Implant failure, Middle Aged, Biomechanical Phenomena, Physiological Parameters, Connective Tissue, Preoperative Period, Engineering and Technology, Legs, Medicine, Female, Anatomy, Knee Prosthesis, Research Article, Biotechnology, medicine.medical_specialty, Science, 0206 medical engineering, Bioengineering, Surgical and Invasive Medical Procedures, Prosthesis Design, Models, Biological, Arthroplasty, Pelvis, 03 medical and health sciences, Musculoskeletal System Procedures, Physical medicine and rehabilitation, medicine, Humans, Computer Simulation, ddc:610, Aged, Ligaments, Hip, Body Weight, Work (physics), Biology and Life Sciences, Gold standard (test), 020601 biomedical engineering, Radiography, Biological Tissue, Body Limbs, Coronal plane, Medical Devices and Equipment
Abstract

PLOS ONE 15(1), e0227272 (2020). doi:10.1371/journal.pone.0227272, Published by PLOS, San Francisco, California, US

Published
2020
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12. Single- versus double-bundle patellar graft insertion for isolated MPFL reconstruction in patients with patellofemoral instability: a systematic review of the literature

Author

Filippo Migliorini, Andromahi Trivellas, Giorgia Colarossi, Björn Rath, Markus Tingart, and Jörg Eschweiler

Subjects
medicine.medical_specialty, MPFL, Patellofemoral instability, Physical examination, Graft, 03 medical and health sciences, Single bundle, 0302 clinical medicine, Double bundle, Revision Surgeries, medicine, Dislocation, Orthopedics and Sports Medicine, In patient, Tendon graft, 030222 orthopedics, medicine.diagnostic_test, business.industry, 030229 sport sciences, General Medicine, Surgery, Arthroscopy and Sports Medicine, Cohort, Orthopedic surgery, Reconstruction, business
Abstract

Archives of orthopaedic and trauma surgery 140(6), 769-776 (2020). doi:10.1007/s00402-020-03376-9, Published by Springer, Berlin ; Heidelberg

Published
2020
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