1. Frequency of Glutathione Reductase, Pyruvate Kinase and Glucose-6-Phosphate Dehydrogenase Deficiency in a Spanish Population
- Author
-
Ángela Casado Moragón, M.E. López-Fernández, and S. C. García
- Subjects
Male ,inorganic chemicals ,Pyruvate decarboxylation ,Pyruvate dehydrogenase lipoamide kinase isozyme 1 ,Pyruvate dehydrogenase kinase ,Enzyme deficiencies ,Pyruvate Kinase ,Glutathione reductase ,Pyruvate dehydrogenase phosphatase ,fluids and secretions ,Gene Frequency ,hemic and lymphatic diseases ,Genetics ,Humans ,Pyruvate kinase ,Glucose-6-phosphate dehydrogenase ,Genetics (clinical) ,Chemistry ,Pyruvate dehydrogenase complex ,Glucosephosphate Dehydrogenase Deficiency ,Glutathione Reductase ,Biochemistry ,Spain ,Female ,Branched-chain alpha-keto acid dehydrogenase complex ,Metabolism, Inborn Errors ,Spanish population - Abstract
The frequencies of deficiencies of glutathione reductase (GSSG-R), pyruvate kinase (PK) and gIucose-6-phosphate dehydrogenase (G6PD) in a Spanish sample are presented. A total of 2,129 individuals was analyzed for GSSG-R, 1,636 for PK, and 1,066 (629 males and 437 females) for G6PD. Beutler’s method was used. The frequencies obtained for these deficiencies were: GSSG-R, 0.09%; PK, 0.24%; and G6PD, 0.79%. The results are discussed.
- Published
- 1979