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1. Melkersson-Rosenthal Syndrome and Acquired C1 Inhibitor Deficiency

Author

Olivier Chosidow, F. Masson, J.C. Piette, S. Agbo-Godeau, H. Szpirglas, Stéphane Barete, V. Frémeaux-Bacchi, and Camille Francès

Subjects
Adult, Male, Pathology, medicine.medical_specialty, C1 inhibitor deficiency, Dermatology, Complement C1 Inactivator Proteins, Complement Hemolytic Activity Assay, Risk Assessment, Sensitivity and Specificity, Severity of Illness Index, Sampling Studies, Macrocheilitis, C1-inhibitor, Rare Diseases, Melkersson–Rosenthal syndrome, Humans, Medicine, Aged, Retrospective Studies, Palsy, Melkersson-Rosenthal Syndrome, biology, business.industry, Complement C4, Complement C3, Middle Aged, Prognosis, medicine.disease, Combined Modality Therapy, biology.protein, Female, business, Biomarkers, Rare disease
Abstract

Background: Melkersson-Rosenthal syndrome (MRS) is a rare disease whose full-blown form is characterized by orofacial swelling, facial palsy and lingua plicata. Objective: To investigate the complement system as well as its role in patients with MRS. Methods: Seven patients presenting at this hospital between November 2002 and May 2003 and meeting the diagnostic criteria according to Hornstein were evaluated retrospectively. The investigations included clinical signs, an analysis of the complement system including levels of CH50, C3, C4, C1 inhibitor (INH) functions and C1-INH antigen detection. Results: Two female patients showed isolated low levels of functional C1-INH as determined by duplicate tests. Both patients took estrogen-progestin contraceptives. Conclusion: Since deficiency in plasma protease C1-INH is known to lead to recurrent angioedema, we hypothesize that low levels of functional C1-INH may have contributed to the orofacial swelling in the 2 patients.

Published
2008

2. Subject Index Vol. 91, 2002

Author

Hiroyuki Sasamura, Olaf Hergesell, K. Tabei, Osamu Hotta, Norio Sunagawa, Ioannis Tzanakis, Emanuela Rizzioli, Mingcai Qiu, Paul F. Laflam, Gian Marco Ghiggeri, Yasufumi Kyuden, D. Ljubanovic, M.J. Nubé, W.E.M. Schouten, Carla Carasi, Joachim Lundahl, Mariko Miyazaki, Isao Ishikawa, Yasuhiko Ueda, Kazuhiko Funabiki, Michael Nomikos, Tatsuo Kobayashi, Maria Magalhães, Manabu Asano, Takayuki Fujita, Shaul M. Shasha, Revital Shurtz-Swirski, Susana Sampaio, H. Furuya, Kefaia El-Sayed Mohamed, Mitsuhiro Satoh, A. Bihorac, Ç. Özener, Renza Cristofani, Ikue Mori-Kudo, U. Assogba, Satoshi Ogata, A.J. van Houte, Shifra Sela, Hidetake Kurihara, Maria Rita Metelli, Kayoko Nomura, Giovanni Montini, Atsushi Satomura, S. Krizanac, Rodo O. von Vigier, Morito Endo, Jürgen Floege, Lara Alonso da Silva, Yasuharu Nomura, Satoko Honda, Manuel Pestana, Hassan Abd-El-Hady Ahmed, Omar da Rosa Santos, P. Cacoub, Toshihiro Shinosaki, Ikuko Miyai, Y. Asano, Yoshiharu Nishitani, Yoshio Taguma, Chien-Liang Chen, Chizuru Ishiguro, P. Xavier, Gianluca Caridi, Marina Martic, Jean-Pierre Guignard, Maura Zanolari Calderari, Akira Saito, Hua-Chang Fang, F. A. W. Kemperman, Huiqi Qu, Atsushi Yamauchi, Hisaya Tada, Gavin J. Becker, Koji Harada, Mohamed Abel-Kader Sobh, Galal Mohamed Amer, Luisa Murer, P A Conz, Hiroyuki Ohi, Ali Moshfegh, Armando A. Mendes, Osama Gheith, Daisuke Suzuki, Fatma Elhusseini, Ciro Tetta, Eugênio Pacelle Queiroz Madeira, Yoshinobu Fuke, Takashi Uzu, Kang-Ju Chou, Savvas Kazoulis, Manuel Palacín, Ioannis Christoulakis, P. Hausfater, G. Kantarcı, Hideyuki Kurioka, Ivano Moschèn, Stefan H. Jacobson, Graziella Zacchello, Satoshi Horikoshi, Atsushi Tsuchida, Ryoko Shimizu-Hirota, Petros Hatzilias, Alberto Bettinelli, Tim D. Hewitson, Raymond T. Krediet, J.C. Piette, Jacek Borawski, S. Tokay, Takafumi Ito, Mutsuo Taiji, Ronit Geron, Makoto Watanabe, M. Schoorl, Carlo Catalano, Pia Thylén, Péter Tóth-Heyn, Ching-Bun Chen, Rajiv Kumar, Shigemi Chiba, Stefan Bröer, Takao Saruta, Mahmoud El-Baz, Yuji Fujita, E. Akoğlu, Roberto Palla, Michał Myśliwiec, Toshiki Inokuchi, Yasuhiko Tomino, Yasuhiro Akai, E. Kusano, Yukiteru Asakimori, Maria Norpoth, Shih-Yuan Hung, Yee-Hsuan Chiou, Kristen J. Kelynack, Hideo Shiiki, Alberto A.E. Bertelli, Mari Kuroda, Yoshihiko Taniguchi, Kazumasa Hamano, Massimiliano Migliori, Steven McTaggart, P. Lebon, Toshio Miyata, Vincenzo Panichi, Gunilla Halldén, Soichi Haraguchi, Mario G. Bianchetti, Po-Tsang Lee, M.P.C. Grooteman, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Yutaka Yaguchi, Florian Lang, Anna Maria Bianchi, Birgit Kallinowski, Mitchell L. Halperin, M. Inoue, Mizuo Mifune, Masayuki Iwano, Masafumi Yamato, Stefano De Pietro, Hiroshi Noguchi, Koji Kuboki, Hsiao-Min Chung, Hideto Sakai, Tomokazu Nagano, Iwan Setiawan, Surinder Cheema-Dhadli, Nobuoki Kohno, Shan Lin, M. Vrkljan, Isao Shirato, Noriaki Yorioka, Adriana MacIntyre Innocenzi, Marcella Normanno, José Gerardo Oliveira, Matsuhiko Hayashi, Y. Ando, Lambertus Arisz, Krystyna Pawlak, Galina Shapiro, Ikuo Horigome, Takashi Furuta, Y. Akai, Batya Kristal, João Ramos, Mahmoud Wageh Rasem, Alexandra Albers, Sarantos Xirakis, Sérgio Fernando Ferreira Santos, Takao Kawamura, Martin Zeier, Hiroo Noshiro, Manuela Della Vella, Daniele Taccola, Isao Ohsawa, K. Galesic, Mie Ko, Sana Sayed Gazarin, Eduardo H. Garin, Guilherme Santoro-Lopes, Mutsuko Hidaka, Luca Giovannini, and Giulietta Sbragia

Subjects
Index (economics), business.industry, Statistics, Medicine, Subject (documents), business
Published
2002

3. Plasma Exchange and Interferon-Alpha Pharmacokinetics in Patients with Hepatitis C Virus-Associated Systemic Vasculitis

Author

Pierre Hausfater, U. Assogba, P. Lebon, Patrice Cacoub, and J.C. Piette

Subjects
Male, Vasculitis, Systemic disease, Hepatitis C virus, Alpha interferon, medicine.disease_cause, hemic and lymphatic diseases, medicine, Humans, Interferon alfa, Aged, Polyarteritis nodosa, business.industry, Interferon-alpha, Plasmapheresis, Middle Aged, medicine.disease, Combined Modality Therapy, Hepatitis C, Virology, Immunology, Female, Viral disease, business, medicine.drug, Systemic vasculitis
Abstract

Different types of vasculitis have been reported in association with hepatitis C virus (HCV) infection, i.e. type II mixed cryoglobulinemia and polyarteritis nodosa (PAN). Therapeutic approach of such severely symptomatic patients include interferon-alpha (IFN) plus plasma exchange (PE). There are no data on IFN pharmacokinetic changes related to PE. Patients and Methods: We studied 7 HCV-infected patients (mean age: 57 years) presenting with symptomatic type II mixed cryoglobulinemia (n = 5) or biopsy-proven PAN (n = 2). All patients underwent subcutaneous IFN therapy with concomitant PE. Serum IFN concentration was measured in serial samples on days with and without PE. Results: Without PE, IFN Cmax (range: 100–750 IU/ml) was obtained 3–6 h after subcutaneous injection, followed by a 3- to 9-hour plateau. IFN concentration declined subsequently reaching a residual concentration 24 h after injection, ranging from 20 to 40 IU/ml. PE performed 6 h after IFN administration resulted in increased IFN clearance in that the concentration-time IFN-α area under the curve decreased from 3,005 IU·h/ml (1,563–4,614) on days without PE to 2,142 IU·h/ml (973–4,123) on day with PE. Conclusions: In patients with HCV-associated vasculitis, PE increase IFN clearance. Combined IFN-α and PE therapy schedule have to be further studied to optimize its biological activity.

Published
2002

4. Contents Vol. 91, 2002

Author

Steven McTaggart, Hisaya Tada, D. Ljubanovic, Gunilla Halldén, M.J. Nubé, Marina Martic, Yasufumi Kyuden, Luisa Murer, Vincenzo Panichi, W.E.M. Schouten, Eugênio Pacelle Queiroz Madeira, Mariko Miyazaki, Yasuhiko Ueda, Hidetake Kurihara, Maria Norpoth, Guilherme Santoro-Lopes, Mutsuko Hidaka, Galal Mohamed Amer, Ali Moshfegh, Carlo Catalano, Chien-Liang Chen, Stefano De Pietro, Koji Kuboki, Ryoko Shimizu-Hirota, P. Hausfater, Susana Sampaio, Yoshinobu Fuke, Manuel Palacín, Luca Giovannini, Savvas Kazoulis, Satoshi Ogata, A.J. van Houte, Ikuo Horigome, Graziella Zacchello, Alberto Bettinelli, Batya Kristal, Tim D. Hewitson, Isao Shirato, Noriaki Yorioka, Makoto Watanabe, Renza Cristofani, Sérgio Fernando Ferreira Santos, Takao Kawamura, Y. Akai, S. Krizanac, Jacek Borawski, Maura Zanolari Calderari, Nobuoki Kohno, Marcella Normanno, Giulietta Sbragia, Iwan Setiawan, U. Assogba, Mitsuhiro Satoh, Mutsuo Taiji, Y. Asano, Mahmoud El-Baz, Daisuke Suzuki, Gavin J. Becker, Akira Saito, Giovanni Montini, Stefan Bröer, Yuji Fujita, Revital Shurtz-Swirski, Paul F. Laflam, P A Conz, Ching-Bun Chen, Ioannis Christoulakis, Toshihiro Shinosaki, Takafumi Ito, Takashi Uzu, Yasuhiro Akai, Kang-Ju Chou, G. Kantarcı, Shan Lin, Atsushi Tsuchida, Hideo Shiiki, Mari Kuroda, Atsushi Satomura, Huiqi Qu, Soichi Haraguchi, Michał Myśliwiec, Masayuki Iwano, Masafumi Yamato, M. Vrkljan, Petros Hatzilias, Yoshihiko Taniguchi, Atsushi Yamauchi, Emanuela Rizzioli, Mingcai Qiu, Mohamed Abel-Kader Sobh, Sana Sayed Gazarin, Shigemi Chiba, M. Schoorl, E. Kusano, Yukiteru Asakimori, Anna Maria Bianchi, Birgit Kallinowski, Mario G. Bianchetti, Armando A. Mendes, Yutaka Yaguchi, Isao Ishikawa, Manuel Pestana, Pia Thylén, M. Inoue, Shifra Sela, Po-Tsang Lee, Massimiliano Migliori, Jean-Pierre Guignard, Olaf Hergesell, P. Lebon, Hideto Sakai, Yee-Hsuan Chiou, Kristen J. Kelynack, Alberto A.E. Bertelli, Osamu Hotta, Shaul M. Shasha, Tomokazu Nagano, Lambertus Arisz, Martin Zeier, H. Furuya, Kefaia El-Sayed Mohamed, A. Bihorac, Ç. Özener, Lara Alonso da Silva, Hiroshi Noguchi, Toshio Miyata, Takao Saruta, E. Akoğlu, Stefan H. Jacobson, Krystyna Pawlak, Ivano Moschèn, Maria Rita Metelli, Hsiao-Min Chung, Takashi Furuta, Adriana MacIntyre Innocenzi, Yoshiharu Nishitani, Kazumasa Hamano, Manabu Asano, Mizuo Mifune, Kayoko Nomura, Tatsuo Kobayashi, Gian Marco Ghiggeri, João Ramos, Mahmoud Wageh Rasem, José Gerardo Oliveira, Hassan Abd-El-Hady Ahmed, Hiroyuki Ohi, S. Tokay, Matsuhiko Hayashi, Osama Gheith, Carla Carasi, P. Xavier, Ikue Mori-Kudo, Hiroo Noshiro, Kazuhiko Funabiki, Michael Nomikos, Chizuru Ishiguro, Ikuko Miyai, Maria Magalhães, Péter Tóth-Heyn, Satoko Honda, Manuela Della Vella, Daniele Taccola, Gianluca Caridi, Yasuharu Nomura, Hideyuki Kurioka, Joachim Lundahl, P. Cacoub, Y. Ando, Ronit Geron, Toshiki Inokuchi, Eduardo H. Garin, Galina Shapiro, Roberto Palla, Shih-Yuan Hung, Yasuhiko Tomino, Ciro Tetta, Surinder Cheema-Dhadli, Alexandra Albers, Sarantos Xirakis, Florian Lang, Mitchell L. Halperin, Hideaki Nakaya, Ken Takahara, Fabio Fabbian, Jürgen Floege, Yoshio Taguma, Koji Harada, Hua-Chang Fang, F. A. W. Kemperman, Satoshi Horikoshi, Rodo O. von Vigier, Morito Endo, Omar da Rosa Santos, Norio Sunagawa, M.P.C. Grooteman, Fatma Elhusseini, Takayuki Fujita, Raymond T. Krediet, J.C. Piette, Rajiv Kumar, Hiroyuki Sasamura, K. Tabei, Ioannis Tzanakis, K. Galesic, Mie Ko, and Isao Ohsawa

Subjects
Traditional medicine, business.industry, Medicine, business
Published
2002

5. Is there a Role for Antithrombotic Therapy in the Prevention of Pregnancy Loss?

Author

J.C. Piette, Bertrand Wechsler, and L T Huong Du

Subjects
Abortion, Habitual, medicine.medical_specialty, Pregnancy, Aspirin, business.industry, Warfarin, Hematology, Heparin, Antiphospholipid Syndrome, medicine.disease, Fibrinolytic Agents, Antiphospholipid syndrome, Prednisone, Physiology (medical), Internal medicine, Immunology, Antithrombotic, medicine, Humans, Female, Adverse effect, business, medicine.drug
Abstract

The antiphospholipid syndrome (APS) is now emerging as an important cause of recurrent pregnancy loss. A variety of treatments, including steroids, aspirin, heparin and immunoglobulin, alone or in combination, have been assessed in experimental studies and in clinical trials. Steroids are no longer recommended as first-line therapy for patients with APS without overt lupus, because they are associated with significant foetal and maternal morbidity. Based on data from recent trials, heparin plus low-dose aspirin appears to be the regimen of choice for patients with APS who have a history of thrombosis or pregnancy losses with aspirin alone. Aspirin is safe in pregnancy. Subcutaneous heparin does not cross the placenta and therefore has no adverse effects on the foetus. For the mother, however, potential side effects of heparin treatment include bleeding, thrombocytopenia and osteoporosis. Warfarin must be avoided during the first trimester but may have a role to play subsequently in certain subsets of patients. Some studies have demonstrated that combined therapy with prednisone and aspirin, or with heparin and aspirin, may improve the outcome in women with autoimmune disorders who are undergoing in-vitro fertilization.

Published
1999

6. Risk Factors for Thrombosis and Bleedings Prevention of Arterial and Venous Thrombosis Treatment of VTE and Adverse Reactions

Author

F.R. Rosendaal, Meyer-Michel Samama, Jeffrey J. Popma, Mark Levine, Graham F. Pineo, Bernd-Jan Sanson, Bertrand Wechsler, Alexander G.G. Turpie, Susanne M. Smorenburg, Sonia S. Anand, Marie-Hélène Horellou, David E. Anderson, Philip S. Wells, Barbara A. Hutten, Per Lindmarker, Fokko J. van der Woude, Le Thi Huong Du, Ulf Lindahl, Deborah L. Ornstein, Shannon M. Bates, Jeffrey I. Weitz, Wee-Shian Chan, Sylvia Haas, Lars Wallentin, Laaban Jp, J.C. Piette, Leo R. Zacharski, Sam Schulman, Martin H. Prins, Harry R. Büller, Russell D. Hull, and Jacqueline Conard

Subjects
medicine.medical_specialty, Venous thrombosis, business.industry, Physiology (medical), Internal medicine, Cardiology, Medicine, Hematology, business, medicine.disease, Thrombosis
Published
1999

7. Contents, Vol. 195, 1997

Author

S.B. Margulis, C. Mann, M.L. Battifoglio, E. Ranieri, J. Yeager, A. Stoehr, Dan Lipsker, R. Viraben, H.G. Skelton, M. Stücker, R. Betti, E. Inselvini, S. Reichert-Penetrat, L.R. Braathen, J. Hafiier, G. Claus, C. Ferrándiz, I. Hadshiew, A. Fujioka, I.K. Hornstra, J. Bazex, A. Friedl, C. Crosti, M. Hiruma, E. Hölzle, F. Drago, H. Laubenthal, B. Couret, I. Bielsa, A. von Felten, E.M. Procaccini, D. Abeck, A. Bonnafoux-Clavere, E.A. Bingham, P.M. Frossard, T. Hunziker, J.M. Carrascosa, J. Rousseau, J. Rügemer, S. Untiedt, P. Clavere, M. Palvarini, W.Y.M. Tang, Philippe Tréchot, Subrata Malakar, E. Weisshaar, T. Reuther, L. Maunoury, A. Reborn, K. Nomura, G. Posteraro, F. Malaguti, A. Traub, S. Palacios, M. Chishiki, R.B. Strieker, F. Stäb, E. Martinez, D.K.B. Armstrong, C. Letawe, E. Piqué, E. Adeghate, J.L. Laporte, H. Gollnick, M. Monika Weber, J.-F. Cuny, K.J. Smith, A. Ishibashi, I. Hashimoto, G.G. Lestringant, J.C. Piette, M.-P. Labarthe, L. Casula, I.H. Galadari, P. Chavaz, C.T. Ammirati, A.W. Gerbig, G. von Kohyletzki, V. Roman, C. Bedane, A. Plettenberg, Gérald Pierard, V. Goffin, P. Bayle-Lebey, W. Meigel, M. Gfesser, H. Banba, K. Bohnsack, M.F. Peake, J.L. Wilde, Akira Kawada, M. Just, Annick Barbaud, E. Losi, P. Hügler, I. Masouyé, Sandipan Dhar, M. Olivares, Jean-Luc Schmutz, K. Hoffmann, M. Ribera, M.A. Hurhi, F. Rippke, M. Gallego, G. Riccio, Jean-Hilaire Saurat, R.B. Lee, R. Disch, J.M. Bonnetblanc, A. Aguilar, J.J. Meffert, Camille Francès, P. Altmeyer, E. Masgrau, G. Monfrecola, K.F. Wagner, J. Ring, B. Gorguet, Lars E. French, and V. Schreiner

Subjects
Dermatology
Published
1997

8. Contents, Vol. 101, 1993

Author

J. Sany, J. Clèdes, M. Dueymes, G.L. Asherson, J. Barrier, Hiroshi Nakajima, Oluseyi A. Vanderpuye, Takehiro Koshio, C. Jorgensen, L. Mjörnstedt, John A. McIntyre, M.C. Caroleo, L. Guillevin, J.C. Piette, K.L. Morgan, J.M. Roe, Kyung Hyo Kim, F. Dieli, D. Mottier, P. Youinou, Rob C. Aalberse, Ernst Gleichmann, V. Colizzi, J.M. Dueymes, Hideharu Endo, A. Bellavia, O. Meyer, H. Yilmaz, A. Lamour, P.Y. Hatron, Akio Yamada, Larry W. Williams, Mariam Al-Laith, K.Y. Chua, C. Series, Markus Uhrberg, M. Olausson, Ricki M. Helm, Carlos A. Labarrere, Koichi Ikizawa, Marjan van den Berg, D.A. Isenberg, C. Massot, Christina Stein, Wim van’t Hof, C. Conri, P.K. Kehal, Yukiyoshi Yanagihara, P. Galanaud, F.L. Pearce, A.A. Drosos, A.L. de Weck, Els van Vliet, R. Maran, B. Kjellson, Wesley Burks, Takao Shida, Dong Soo Kim, David E. Milne, Sho Yoshida, John R. Vane, J.F. Besancenot, B. Grobois, A. Salerno, Itsuo Iwamoto, L. Wramner, H.M. Moutsopoulos, M. Mattei, Keiichi Kajiwara, Peter C. Driedijk, M. Longy-Boursier, G. Dien, J. Jouquan, Richard J. Brenner, T. Söderström, Y. Shoenfeld, W.R. Thomas, P. Philippe, and P. Le Goff

Subjects
business.industry, Immunology, Immunology and Allergy, Medicine, General Medicine, business
Published
1993

9. Two Enlarged Kidneys: A Manifestation of Erdheim-Chester Disease

Author

J.C. Piette, N. Costes Chalret, B. Wechsler, Olivier Aumaître, J. Ponsonnaille, Marc André, I. Delèvaux, and B. de Fraissinette

Subjects
Male, Pathology, medicine.medical_specialty, Histiocytosis, Non-Langerhans-Cell, Heart disease, business.industry, macromolecular substances, Middle Aged, Kidney, medicine.disease, Nephropathy, Histiocytosis, Pericarditis, medicine.anatomical_structure, Nephrology, Erdheim–Chester disease, medicine, Humans, Abdomen, Kidney Diseases, Bone Diseases, Enlarged kidney, business, Kidney disease
Abstract

Erdheim-Chester disease is a rare form of non-Langerhans’ cell histiocytosis. This disorder is characterized by a bone involvement and several extraskeletal manifestations. We describe the case of a patient with a pleural and pericardial effusion leading to tamponade. Pathological examination of pericardium and mediastinal adenopathy was normal. The abdominal computed tomography scan showed two enlarged kidneys suggestive of Erdheim-Chester disease. Bone scan scintigraphy demonstrated symmetrical increased labeling of the long bones. The biopsy of perirenal soft tissue confirmed the diagnosis of Erdheim-Chester disease.

Published
2001

10. Annular Atrophic Lichen planus and Sneddon’s Syndrome

Author

J.C. Piette, J.L. Laporte, L. Maunoury, Camille Francès, and Dan Lipsker

Subjects
Adult, Male, medicine.medical_specialty, Pathology, animal structures, Dermatology, Atrophy, Hyperpigmentation, medicine, Humans, skin and connective tissue diseases, Skin pathology, Skin, Arteritis, integumentary system, business.industry, Incidence, Lichen Planus, Follow up studies, Livedo racemosa, Elastic Tissue, medicine.disease, Internal elastic lamina, Sneddon Syndrome, Annular atrophic lichen planus, Arterioles, stomatognathic diseases, Sneddon's syndrome, medicine.symptom, Abnormality, business, Follow-Up Studies
Abstract

We report the case of a patient who had 2 rare diseases, annular atrophic lichen planus (AALP) and Sneddon's syndrome (SNS). This patient had also digital nodules with histological abnormalities suggestive of SNS vasculopathy, which have not been reported so far. AALP is the most rare of all varieties of lichen planus since this case is the third reported to date. The association of livedo racemosa and cerebrovascular disease is the hallmark of SNS, the incidence of which is estimated to be 4 cases per year per million inhabitants. In both diseases, an abnormal production of elastic-tissue-degrading enzymes or a constitutional abnormality of the elastic tissue can be postulated, since SNS is characterized by arteriolar changes with deterioration of the internal elastic lamina and AALP by destruction of the dermal elastic tissue.

Published
1997

11. Acknowledgment to Referees for Dermatology 1997

Author

G. Riccio, Jean-Hilaire Saurat, A. Ishibashi, F. Rippke, C. Letawe, I. Bielsa, A. von Felten, G.G. Lestringant, M.-P. Labarthe, Philippe Tréchot, I.H. Galadari, I.K. Hornstra, M. Gallego, Camille Francès, M. Ribera, S. Untiedt, M. Palvarini, J. Rügemer, G. von Kohyletzki, A. Bonnafoux-Clavere, E.A. Bingham, M. Monika Weber, A. Aguilar, P.M. Frossard, C. Mann, T. Hunziker, M.A. Hurhi, W.Y.M. Tang, A. Stoehr, M.L. Battifoglio, T. Reuther, P. Clavere, G. Posteraro, J. Ring, Sandipan Dhar, S. Reichert-Penetrat, E. Inselvini, A. Traub, S. Palacios, J. Hafiier, A. Reborn, L. Maunoury, C. Ferrándiz, M. Olivares, E. Hölzle, J. Bazex, R.B. Strieker, F. Drago, P. Altmeyer, H.G. Skelton, A. Friedl, J.J. Meffert, G. Claus, K. Hoffmann, R. Betti, E. Masgrau, E. Piqué, J.M. Carrascosa, B. Gorguet, E.M. Procaccini, I. Masouyé, R.B. Lee, R. Disch, B. Couret, J. Rousseau, S.B. Margulis, P. Chavaz, C.T. Ammirati, K. Nomura, F. Malaguti, Jean-Luc Schmutz, D. Abeck, H. Laubenthal, H. Gollnick, J.M. Bonnetblanc, H. Banba, K. Bohnsack, A.W. Gerbig, A. Plettenberg, Gérald Pierard, V. Goffin, J.L. Laporte, Akira Kawada, G. Monfrecola, I. Hashimoto, P. Bayle-Lebey, Dan Lipsker, Subrata Malakar, K.F. Wagner, R. Viraben, P. Hügler, J.C. Piette, W. Meigel, J. Yeager, Lars E. French, F. Stäb, V. Schreiner, L.R. Braathen, E. Adeghate, C. Crosti, V. Roman, E. Weisshaar, E. Martinez, D.K.B. Armstrong, I. Hadshiew, A. Fujioka, L. Casula, M. Gfesser, M. Chishiki, C. Bedane, M.F. Peake, J.L. Wilde, M. Just, Annick Barbaud, E. Losi, J.-F. Cuny, K.J. Smith, E. Ranieri, M. Stücker, and M. Hiruma

Subjects
medicine.medical_specialty, business.industry, Family medicine, Medicine, Dermatology, business
Published
1997

12. Chloroquine-Quinacrine Association in Resistant Cutaneous Lupus

Author

Dan Lipsker, Patrice Cacoub, Pierre Godeau, J.C. Piette, and Camille Francès

Subjects
medicine.medical_specialty, Lupus erythematosus, Chloroquine, business.industry, medicine, Dermatology, Drug resistance, medicine.disease, business, Cutaneous lupus, medicine.drug
Published
1995

13. Anti-β2-Glycoprotein I Antibodies in Sneddon’s Syndrome

Author

Jean-Paul Viard, Camille Francès, J.C. Piette, and A. Tourbah

Subjects
Pathology, medicine.medical_specialty, biology, Vascular disease, business.industry, Dermatology, medicine.disease, Anti β2 glycoprotein i, Immunology, medicine, biology.protein, Beta 2-Glycoprotein I, Sneddon's syndrome, Antibody, business
Published
1993

14. Contents, Vol. 178, 1989

Author

I.W. Simson, S. Watanabe, Kazuhito Hayakawa, Serdar Diker, A.M. Piette, Geoffrey Falkson, A. S. Alberts, B. Wechsler, Emilio Berti, Elvio Alessi, Celale Hin.R. Çelebi, B. Tribout, Rıfkı Hazıroğlu, Antonella Tosti, L. Drouet, Yuichiro Yamasaki, Camille Francès, Thomas L. Diepgen, J.C. Piette, G. Biolcati, L. D’Alessandro Gandolfo, Raffaele Gianotti, E. J. Schulz, D. Griso, Takashi Harada, Blétry O, A. Macri, Y. Merot, Toshio Mochizuki, A.C. Grade, Maria A. Coccia-Portugal, Manigé Fartasch, B.P.M. Martens, Y. Amir, Pier Alessandro Fanti, Murat Yurdakök, Pierre Godeau, Otto P. Hornstein, G. C. Topi, B.M. Czarnetzki, Takeji Nishikawa, Hiroshi Shimizu, Masayuki Amagai, I. Varsano, Sylvie Boisnic, A. Mooy, Philippe Bernard, and Tanaka Shuei

Subjects
Dermatology
Published
1989

15. Cutaneous Necrosis Associated with the Lupus Anticoagulant

Author

A.M. Piette, Pierre Godeau, B. Tribout, Camille Francès, B. Wechsler, J.C. Piette, L. Drouet, Sylvie Boisnic, and Blétry O

Subjects
Adult, Pathology, medicine.medical_specialty, Necrosis, medicine.medical_treatment, Dermatology, Methylprednisolone, immune system diseases, Immunopathology, medicine, Humans, Lupus Erythematosus, Systemic, skin and connective tissue diseases, Autoantibodies, Skin, Leg, Lupus anticoagulant, Lupus erythematosus, business.industry, Plasmapheresis, Middle Aged, medicine.disease, Connective tissue disease, Blood Coagulation Factors, Cutaneous necrosis, Lupus Coagulation Inhibitor, Female, medicine.symptom, business, Complication
Abstract

Extensive cutaneous necrosis of the limbs with sudden onset was observed in 3 women suffering from benign systemic lupus erythematosus. All 3 had a circulating anticoagulant and a positive venereal diseases reference laboratory test without anticardiolipin antibodies.They were successfully treated with pulse methylprednisolone therapy and plasmapheresis. The necrosis-lupus anticoagulant relationship is discussed due to the absence of another possible etiology for cutaneous necrosis and the latter’s histological aspect, i.e. thromboses of the dermal and hypodermal vessels without vasculitis. This cutaneous necrosis resembles that observed in congenital protein C deficiencies and favors the hypothesis of interaction between the lupus anticoagulant and the protein C-S complex.

Published
1989

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