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Your search keyword '"Gold Sodium Thiomalate toxicity"' showing total 8 results
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8 results on '"Gold Sodium Thiomalate toxicity"'

1. Heavy metal nephropathy of rodents.

Author

Payne BJ and Saunders LZ

Subjects
Adenoma chemically induced, Adenoma pathology, Adenoma veterinary, Animals, Cadmium toxicity, Female, Gold toxicity, Gold Sodium Thiomalate toxicity, Kidney pathology, Kidney Neoplasms chemically induced, Kidney Neoplasms pathology, Kidney Neoplasms veterinary, Lead Poisoning pathology, Lead Poisoning veterinary, Male, Mercury Poisoning pathology, Mercury Poisoning veterinary, Mice, Nephrosclerosis chemically induced, Nephrosclerosis pathology, Nephrosclerosis veterinary, Rats, Kidney Diseases veterinary, Metals toxicity, Rodent Diseases chemically induced
Abstract

Heavy metal nephropathy is a pathologic entity of the renal tubular epithelium of rats, evoked by lead, gold, and other heavy metals. It is characterized acutely by coagulative necrosis, subacutely by cortical fibrosis, and chronically by cytomegaly and karyomegaly. Finally, adenomas develop, some of which become malignant.

Published
1978
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2. The effects of gold-containing compounds on pregnant rabbits and their fetuses.

Author

Szabo KT, DiFebbo ME, and Phelan DG

Subjects
Abdominal Muscles abnormalities, Abnormalities, Drug-Induced etiology, Animals, Aurothioglucose administration & dosage, Aurothioglucose analogs & derivatives, Aurothioglucose toxicity, Body Weight, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Female, Fetus anatomy & histology, Gold Sodium Thiomalate toxicity, Hernia, Umbilical chemically induced, Hernia, Umbilical veterinary, Organophosphorus Compounds administration & dosage, Organophosphorus Compounds toxicity, Pregnancy, Fetus drug effects, Gold toxicity, Pregnancy, Animal drug effects, Rabbits, Teratogens
Published
1978
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3. Sarcoma at the injection site of gold sodium thiomalate.

Author

Payne BJ

Subjects
Animals, Female, Fibrosarcoma chemically induced, Fibrosarcoma pathology, Gold Sodium Thiomalate administration & dosage, Injections, Intramuscular, Male, Rats, Rhabdomyosarcoma chemically induced, Rhabdomyosarcoma pathology, Soft Tissue Neoplasms pathology, Carcinogens, Gold Sodium Thiomalate toxicity, Sarcoma, Experimental chemically induced, Soft Tissue Neoplasms chemically induced
Published
1978
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4. The toxicity of three gold compounds in laboratory animals.

Author

Payne BJ and Walz DT

Subjects
Administration, Oral, Animals, Aurothioglucose administration & dosage, Aurothioglucose analogs & derivatives, Aurothioglucose toxicity, Gold administration & dosage, Gold Sodium Thiomalate administration & dosage, Gold Sodium Thiomalate toxicity, Injections, Intramuscular, Lethal Dose 50, Mice, Organophosphorus Compounds administration & dosage, Organophosphorus Compounds toxicity, Phosphines administration & dosage, Phosphines toxicity, Rats, Animals, Laboratory, Gold toxicity
Published
1978
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5. Dose range and sighting study of gold sodium thiomalate in rats.

Author

Payne BJ and Sekella RJ

Subjects
Adenoma chemically induced, Animals, Dose-Response Relationship, Drug, Female, Fibrosarcoma chemically induced, Injections, Intramuscular, Kidney Neoplasms chemically induced, Kidney Tubular Necrosis, Acute chemically induced, Male, Pancreatic Diseases chemically induced, Rats, Gold Sodium Thiomalate toxicity
Published
1978
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6. The acute nephrotoxicity of gold sodium thiomalate.

Author

Payne BJ and Rhodes DC

Subjects
Animals, Blood Urea Nitrogen, Female, Kidney Cortex pathology, Kidney Tubular Necrosis, Acute pathology, Male, Rats, Acute Kidney Injury chemically induced, Gold Sodium Thiomalate toxicity, Kidney Tubular Necrosis, Acute chemically induced
Published
1978
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7. The effects of gold-containing compounds on pregnant rats and their fetuses.

Author

Szabo KT, Guerriero FJ, and Kang YJ

Subjects
Abnormalities, Drug-Induced veterinary, Animals, Aurothioglucose analogs & derivatives, Aurothioglucose toxicity, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Female, Gold Sodium Thiomalate toxicity, Phosphines toxicity, Pregnancy, Fetus drug effects, Gold toxicity, Pregnancy, Animal drug effects, Rats, Teratogens
Published
1978
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8. The subacute and chronic toxicity of SK&F 36914, SK&F D-39162 and gold sodium thiomalate in rats.

Author

Payne BJ and Arena E

Subjects
Adenoma chemically induced, Administration, Oral, Animals, Aurothioglucose administration & dosage, Aurothioglucose toxicity, Drug Evaluation, Preclinical, Female, Gold administration & dosage, Gold Sodium Thiomalate administration & dosage, Injections, Intramuscular, Intestinal Diseases chemically induced, Intestinal Diseases pathology, Kidney Neoplasms chemically induced, Male, Organophosphorus Compounds administration & dosage, Phosphines administration & dosage, Phosphines toxicity, Rats, Stomach Diseases chemically induced, Ulcer chemically induced, Aurothioglucose analogs & derivatives, Gold analogs & derivatives, Gold toxicity, Gold Sodium Thiomalate toxicity, Organophosphorus Compounds toxicity
Published
1978
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