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1. Successful prevention of multidrug resistant HIV mother-to-child transmission with enfuvirtide use in late pregnancy.

Author

Madeddu G, Calia GM, Campus ML, Lovigu C, Mannazzu M, Olmeo P, Mela MG, and Mura MS

Subjects
Adult, CD4 Lymphocyte Count, Enfuvirtide, Female, HIV Infections drug therapy, HIV Infections prevention & control, HIV Infections transmission, Humans, Infant, Newborn, Pregnancy, Treatment Outcome, Cesarean Section, Drug Resistance, Multiple, Viral, HIV Envelope Protein gp41 therapeutic use, HIV Fusion Inhibitors therapeutic use, Infectious Disease Transmission, Vertical prevention & control, Peptide Fragments therapeutic use, Pregnancy Complications, Infectious drug therapy
Abstract

The availability of antiretroviral therapy has dramatically reduced the risk of HIV mother-to-child transmission (MTCT). However, mothers infected with multidrug resistant HIV (MDR-HIV) are at increased risk of MTCT. We report the case of a pregnant patient infected with MDR-HIV in whom MTCT was avoided with enfuvirtide use in late pregnancy and elective caesarean section.

Published
2008
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