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2 results on '"Finn Boesen"'

1. Can inpatient multidisciplinary rehabilitation improve health-related quality of life in MS patients on the long term – The Danish MS Hospitals Rehabilitation Study

Author

Anders Guldhammer Skjerbæk, Philipp Trénel, Michael Nørgaard, Thor Petersen, Brita Løvendahl, Finn Boesen, and Peter Vestergaard Rasmussen

Subjects
medicine.medical_specialty, Multiple Sclerosis, Denmark, Health-related quality of life, multiple sclerosis, Danish, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Short Reports, Humans, Medicine, 030212 general & internal medicine, multidisciplinary rehabilitation, Rehabilitation Study, Health related quality of life, Inpatients, business.industry, humanities, Hospitals, language.human_language, Term (time), Neurology, Quality of Life, language, Physical therapy, long term, Neurology (clinical), business, 030217 neurology & neurosurgery, Multidisciplinary rehabilitation
Abstract

Background: Inpatient multidisciplinary rehabilitation (MDR) can improve health-related quality of life (HRQoL) in multiple sclerosis (MS) patients. However, the evidence of a long-term benefit is limited. Objectives: To investigate the long-term effectiveness of inpatient MDR on HRQoL in MS patients. Methods: We conducted a randomized controlled partial crossover trial with 427 MS patients. Results: Statistical significant long-term improvements in HRQoL were found in three of the six outcome measures at 12-month follow-up. Three in four suggested minimal clinically important differences (MCIDs) were unmet. Conclusion: These results indicate that the administration of inpatient MDR may lead to long-lasting improvements in HRQoL in MS patients.

Published
2019

2. Longer term effectiveness of inpatient multidisciplinary rehabilitation on health-related quality of life in MS patients: a pragmatic randomized controlled trial – The Danish MS Hospitals Rehabilitation Study

Author

Philipp Trénel, Finn Boesen, Peter Vestergaard Rasmussen, Brita Løvendahl, Jan Sørensen, Thor Petersen, and Michael Nørgaard

Subjects
Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Denmark, medicine.medical_treatment, Hospitals, Rehabilitation, multiple sclerosis, inpatient, rehabilitation, law.invention, Treatment and control groups, Danish, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Randomized controlled trial, law, Outcome Assessment, Health Care, Outpatients, medicine, Humans, 030212 general & internal medicine, pragmatic clinical trial, Rehabilitation Study, Patient Care Team, Inpatients, Rehabilitation, Expanded Disability Status Scale, Multidisciplinary rehabilitation, business.industry, Multiple sclerosis, Neurological Rehabilitation, Middle Aged, medicine.disease, language.human_language, quality of life, Neurology, randomized controlled trial, Quality of Life, Physical therapy, language, Female, Neurology (clinical), business, Original Research Papers, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Background: There is insufficient evidence to support the effectiveness of multidisciplinary rehabilitation on the health-related quality of life (HRQoL) of MS patients. Objectives: To evaluate the longer term effectiveness of inpatient multidisciplinary rehabilitation on the HRQoL of MS patients. Methods: The study was a two-hospital, pragmatic, randomized controlled trial with a 6-month follow-up. Patients aged 18–65 years with MS and Expanded Disability Status Scale scores ≤7.5 were randomly assigned (1:1) to 4 weeks of inpatient multidisciplinary rehabilitation (20 days of scheduled rehabilitation) or 6 months on a wait list. The outcome measures were Functional Assessment in Multiple Sclerosis (FAMS), Multiple Sclerosis Impact Scale-29 (MSIS-29), EQ-5D-5L and 15D. Results: We randomized 213 patients to the wait-list control group and 214 patients to the treatment group. Trends in favour of the treatment group were observed across all measures. However, the difference was significant in only two of the six measures. The treatment effect was −2.7 (95% CI: −5.6 to (−0.1)), p = 0.046) for the MSIS-29 Psychological and 0.017 (95% CI: 0.005–0.030, p = 0.008) for the 15D. FAMS, which we used to calculate the sample size, was not significant. Conclusion: The results indicated that inpatient multidisciplinary rehabilitation is effective in improving the HRQoL of MS patients after 6 months.

Published
2017

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