1. Predictive value of magnetic resonance imaging signal and contrast-enhancement characteristics on post-embolization volume reduction of uterine fibroids
- Author
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Ş. ZeteroĞlu, Ömer Etlik, M. Şengül, Halil Arslan, and Mustafa Harman
- Subjects
Adult ,Gadolinium DTPA ,medicine.medical_specialty ,Contrast enhancement ,Uterine fibroids ,medicine.medical_treatment ,Contrast Media ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,medicine ,Humans ,Volume reduction ,Radiology, Nuclear Medicine and imaging ,Postoperative Period ,Prospective Studies ,Embolization ,Observer Variation ,Uterine leiomyoma ,Leiomyoma ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Uterus ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Image Enhancement ,medicine.disease ,Embolization, Therapeutic ,Magnetic Resonance Imaging ,Predictive value ,female genital diseases and pregnancy complications ,Treatment Outcome ,Polyvinyl Alcohol ,030220 oncology & carcinogenesis ,Uterine Neoplasms ,Female ,Radiology ,business ,After treatment ,Follow-Up Studies - Abstract
Purpose: To assess the magnetic resonance imaging (MRI) signal and contrast-enhancement features of uterine fibroids before and after embolization, and to determine whether or not there are pre-embolization MRI characteristics that predict the volume reduction of fibroids. Material and Methods: Uterine fibroid embolization (UFE) was carried out in 28 fibroids of 20 patients, all of whom were symptomatic. The patients were prospectively evaluated with T1-weighted, T2-weighted, and gadolinium-enhanced T1 MRI sequences before and 6 months after embolization. The relationship between the characteristics of MRI signal and contrast-enhancement features of fibroids before the procedure and the change in size of the lesions after treatment was investigated. Results: Before embolization, the mean volume of fibroids was 123 cm3 (8–560 cm3). The decrease rate in fibroid volumes was 44.6% (range 7–70%) 6 months after embolization. Volume reduction was more prominent in fibroids that had a high signal intensity on T2-weighted images and a marked contrast enhancement on T1-weighted images ( P Conclusion: MRI is an effective method for revealing size and signal changes of fibroids after embolization. MRI signal characteristics and the contrast-enhancement pattern of fibroids before embolization can predict tumor volume reduction after embolization.
- Published
- 2006
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