36 results on '"Mackler L"'
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2. Advancing Clinical Evaluation and Treatment of Arthrogenic Muscle Inhibition: A Need for Validation and Innovation-Letter to the Editor.
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Norte GE, Sherman DA, Rush JL, Ingersoll CD, Bodkin SG, Snyder-Mackler L, Grindstaff TL, Burland JP, Hopkins JT, Blackburn T, Chaput M, Konishi Y, Rice DA, Hart JM, Harkey MS, Zarzycki R, Palmieri-Smith RM, Lepley LK, Lepley AS, Pamukoff DN, Park J, Lisee C, Pietrosimone B, Thomas AC, Goetschius J, Tourville TW, Kidgell DJ, and Kuenze CM
- Abstract
Competing Interests: One or more of the authors has declared the following potential conflict of interest or source of funding: T.B. is a co-inventor for a patent-pending rehabilitation device demonstrated to acutely reduce AMI (US patent application No. 17/914,305). AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto.
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- 2024
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3. Female Athletes With Better Psychological Readiness Are at Higher Risk for Second ACL Injury After Primary ACL Reconstruction.
- Author
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Zarzycki R, Cummer K, Arhos E, Failla M, Capin JJ, Smith AH, and Snyder-Mackler L
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- Humans, Female, Quality of Life, Prospective Studies, Return to Sport psychology, Athletes psychology, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Injuries psychology
- Abstract
Background: Approximately 1 in 4 athletes returning to sports will sustain a second anterior cruciate ligament (ACL) injury. Psychological factors related to kinesiophobia, confidence, and psychological readiness are associated with second ACL injury; however, the evidence is conflicting., Hypothesis: Athletes who sustain a second ACL injury (ie, graft rupture or contralateral ACL rupture) within 2 years of ACL reconstruction (ACLR) would have greater kinesiophobia, less confidence, and lower psychological readiness prior to return to sport (RTS) compared with athletes who do not sustain a second ACL injury., Study Design: Secondary analysis of a prospective randomized trial., Level of Evidence: Level 3., Methods: A total of 39 female Level I/II athletes completed the following measures after postoperative rehabilitation and a 10-session RTS and second ACL injury prevention program: ACL Return to Sport after Injury (ACL-RSI) scale, the 11-item Tampa Scale of Kinesiophobia (TSK-11), and question 3 on the Knee injury and Osteoarthritis Outcome Score (KOOS) quality of life (QoL) subscale. Athletes were dichotomized based on whether they sustained a second ACL injury within 2 years of ACLR or not. Independent t tests determined group differences in TSK-11, KOOS-QoL, ACL-RSI, and the 3 individual components of the ACL-RSI (ie, emotions, confidence, risk appraisal)., Results: Nine athletes sustained a second ACL injury (4 graft ruptures and 5 contralateral ACL ruptures). The group that sustained a second ACL injury had higher scores on the ACL-RSI ( P = 0.03), higher on the risk appraisal questions of the ACL-RSI ( P < 0.01), and met RTS criteria sooner than athletes who did not ( P = 0.04). All second ACL injuries occurred in athletes who underwent primary ACLR with hamstring tendon autografts., Conclusion: Athletes who sustained a second ACL within 2 years of ACLR had a more positive psychological outlook, higher scores on the specific questions related to the risk appraisal construct of the ACL-RSI, and met RTS criteria sooner than athletes who did not sustain a second ACL injury., Clinical Relevance: Counseling athletes about delaying RTS to reduce the risk of second ACL injury may be especially important in athletes who display high psychological readiness and meet RTS criteria sooner., Competing Interests: The following authors declared potential conflicts of interest: R.Z. received a grant from the National Institutes of Health (NIH) for his PhD and received salary support via grant NCT04504344. E.A. received a grant from the NIH for salary support, and a grant from the Foundation for Physical Therapy Research PODS Level II Scholarship in support of her doctoral thesis. J.J.C. received a grant from the NIH, a grant from ACL-SPORTS randomized controlled trial, a Career Development Award from the Academy of Orthopaedic Physical Therapy, a grant from Veterans Health Administration Eastern Colorado Geriatric Research, Education, and a grant from the Clinical Center Advanced Geriatrics Fellowship. L.S.-M. consulted on an NIH research grant from the University of Kentucky, an NIH research grant from the University of Michigan, and the Brigham & Women’s Orthopedics Sports’ new research and performance center, and is also on the National Football League Scientific Advisory.
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- 2024
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4. Four Distinct 5-Year Trajectories of Knee Function Emerge in Patients Who Followed the Delaware-Oslo ACL Cohort Treatment Algorithm.
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Pedersen M, Grindem H, Berg B, Engebretsen L, Axe MJ, Snyder-Mackler L, and Risberg MA
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- Algorithms, Cohort Studies, Delaware, Humans, Knee Joint surgery, Anterior Cruciate Ligament Injuries surgery, Knee Injuries surgery
- Abstract
Background: Impairments and dysfunction vary considerably after anterior cruciate ligament (ACL) injury, and distinct subgroups may exist., Purpose: (1) To identify subgroups of patients with ACL injury who share common trajectories of patient-reported knee function from initial presentation to 5 years after a treatment algorithm where they chose either ACL reconstruction (ACLR) plus rehabilitation or rehabilitation alone. (2) To assess associations with trajectory affiliation., Study Design: Cohort study; Level of evidence, 3., Methods: We included 276 patients with a acute first-time complete unilateral ACL injury. All patients underwent a 5-week neuromuscular and strength training program before a shared decision-making process about treatment. Within their latest attended follow-up, 62% of patients had undergone early ACLR (<6 months after the 5-week program), 11% delayed ACLR (>6 months after the 5-week program), and 27% progressive rehabilitation alone. Patients completed the International Knee Documentation Committee Subjective Knee Form (IKDC-SKF) at inclusion, after the 5-week program, and at 6 months, 1 year, 2 years, and 5 years after ACLR or completion of the 5-week program (patients treated with rehabilitation alone). We used group-based trajectory modeling to identify trajectories of IKDC-SKF and multinomial logistic regression to assess associations with trajectory affiliation., Results: Four distinct trajectories of IKDC-SKF were identified: Low (n = 22; 8.0% of the cohort), Moderate (n = 142; 51.4%), High (n = 105; 38.0%), and High Before Declining (n = 7; 2.5%). The High trajectory had higher scores at inclusion than the Moderate trajectory, but both improved considerably within 1 year and had thereafter stable high scores. The High Before Declining trajectory also started relatively high and improved considerably within 1 year but experienced a large deterioration between 2 and 5 years. The Low trajectory started low and had minimal improvement. New knee injuries were important characteristics of the High Before Declining trajectory, concomitant meniscal injuries were significantly associated with following the Low (vs Moderate) trajectory, and early/preoperative quadriceps strength and hop symmetry (measured at inclusion) were significantly associated with following the High (vs Moderate) trajectory., Conclusion: We identified 4 distinct 5-year trajectories of patient-reported knee function, indicating 4 subgroups of patients with ACL injury. Importantly, 88% of the patients who followed our treatment algorithm followed the Moderate and High trajectories characterized by good improvement and high scores. Due to eligibility criteria and procedures in our cohort, we can only generalize our model to athletes without major concomitant injuries who follow a similar treatment algorithm. Concomitant meniscal injuries and new knee injuries were important factors in the unfavorable Low and High Before Declining trajectories. These associations were exploratory but support the trajectories' validity. Our findings can contribute to patient education about prognosis and underpin the importance of continued secondary injury prevention.
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- 2022
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5. ACL Reconstruction Rehabilitation: Clinical Data, Biologic Healing, and Criterion-Based Milestones to Inform a Return-to-Sport Guideline.
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Brinlee AW, Dickenson SB, Hunter-Giordano A, and Snyder-Mackler L
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- Activities of Daily Living, Humans, Return to Sport, Anterior Cruciate Ligament Injuries psychology, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction rehabilitation, Biological Products
- Abstract
Context: Anterior cruciate ligament (ACL) reconstruction (ACLR) and postoperative rehabilitation continues to be a multidisciplinary focus in both research and clinical environments. Recent research on ACLR warrants a reexamination of clinicians' current rehabilitation practices to optimize the strikingly variable clinical outcomes after ACLR and return to sport. The purpose of the article and updated guidelines is to use contemporary evidence to systematically revisit our practice guidelines and validate our clinical milestones with data from our university-based practice., Evidence Acquisition: Using the PubMed search engine, articles that reported on ACLR rehabilitation and protocols, guidelines, graft type, healing and strain, return to sport, psychological considerations, and secondary injury prevention published from 1979 to 2020 were identified using the search terms ACLR protocols , guidelines , ACLR rehabilitation , ACL graft , ACL open kinetic chain (OKC) exercise and closed kinetic chain (CKC) exercise , ACLR return to sport , ACLR psychological factors , and ACL injury prevention ., Study Design: Clinical review., Level of Evidence: Level 5., Results: Clinical milestones after ACLR were validated using clinical data collected from 2013 to 2017 at a university-based practice. Variables including knee joint range of motion, effusion, Knee Outcome Survey-Activities of Daily Living Scale, and quadriceps strength index were tracked throughout rehabilitation and analyzed to help inform an updated ACLR rehabilitation guideline., Conclusion: Incorporating the latest research, combined with direct clinical data, provides a current, realistic, and clinically benchmarked strategy for ACLR rehabilitation. Commonly held clinical beliefs regarding rehabilitation after ACL injury must be challenged by the latest research to improve patient outcomes and decrease the risk of reinjury. Key updates to the practice guidelines include the use of frequent and accurate quadriceps strength testing, delayed return-to-sport timeline, immediate use of open kinetic chain exercise, criterion-based progressions for running, sprinting, plyometrics, agility, cutting/pivoting, return to competition, and the inclusion of a secondary prevention program after return to sport., Strength of Recommendation Taxonomy (sort): B.
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- 2022
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6. Association of the Psychological Response to the ACL-SPORTS Training Program and Self-reported Function at 2 Years After Anterior Cruciate Ligament Reconstruction.
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Zarzycki R, Arhos E, Failla M, Capin J, Smith AH, and Snyder-Mackler L
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- Cohort Studies, Humans, Quality of Life, Return to Sport, Self Report, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction
- Abstract
Background: Psychological readiness to return to sport has emerged as an important factor associated with outcomes after anterior cruciate ligament reconstruction (ACLR). Psychological factors are potentially modifiable during the course of rehabilitation, and improving them may lead to better outcomes., Purpose: To determine whether athletes with a positive psychological response after participation in a neuromuscular training and second injury prevention program had better self-reported function and activity outcomes compared with athletes who did not have a meaningful change., Study Design: Cohort study; Level of evidence, 3., Methods: After ACLR and the completion of formal rehabilitation, 66 level I/II athletes completed the following self-reported measures at enrollment (pretraining): the Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) scale, the International Knee Documentation Committee (IKDC) subjective knee form, and the 5 subscales of the Knee injury and Osteoarthritis Outcome Score (KOOS). Participants completed these measures after 10 sessions of agility, plyometric, and progressive strength training and at 1 and 2 years after ACLR. Participants who displayed an increase in the ACL-RSI score from pretraining to posttraining that exceeded the minimal clinically important difference (≥10 points) were defined as having a positive psychological response (responders) to training, and those who did not were defined as nonresponders. A mixed-model analysis of variance was used to determine if group differences in IKDC and KOOS scores existed over the 4 time points (pretraining, posttraining, and the 1- and 2-year follow-ups)., Results: The responders reported better self-reported function compared with the nonresponders, regardless of time, on the IKDC form ( P = .001), KOOS-Sport and Recreation ( P = .014), KOOS-Pain ( P = .007), and KOOS-Symptoms ( P = .002) but not on the KOOS-Quality of Life ( P = .078). Overall, 77% of responders and 67% of nonresponders returned to their previous level of sport by 1 year after ACLR ( P = .358), and 82% of responders and 78% of nonresponders returned to their previous level of sport by 2 years after ACLR ( P = .668)., Conclusion: Ultimately, 59% of the athletes in this study displayed a meaningful improvement in their psychological outlook over the course of the training program. Responders demonstrated persistently better self-reported function at posttraining and at 1 and 2 years after ACLR, but there were no between-group differences in return-to-sport rates.
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- 2021
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7. Quadriceps Strength Symmetry Does Not Modify Gait Mechanics After Anterior Cruciate Ligament Reconstruction, Rehabilitation, and Return-to-Sport Training.
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Arhos EK, Capin JJ, Buchanan TS, and Snyder-Mackler L
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- Adolescent, Adult, Anterior Cruciate Ligament Injuries surgery, Biomechanical Phenomena, Cross-Sectional Studies, Female, Humans, Knee Joint surgery, Male, Quadriceps Muscle anatomy & histology, Young Adult, Anterior Cruciate Ligament Reconstruction rehabilitation, Gait Analysis, Muscle Strength, Quadriceps Muscle physiology, Return to Sport
- Abstract
Background: After anterior cruciate ligament (ACL) reconstruction (ACLR), biomechanical asymmetries during gait are highly prevalent, persistent, and linked to posttraumatic knee osteoarthritis. Quadriceps strength is an important clinical measure associated with preoperative gait asymmetries and postoperative function and is a primary criterion for return-to-sport clearance. Evidence relating symmetry in quadriceps strength with gait biomechanics is limited to preoperative and early rehabilitation time points before return-to-sport training., Purpose/hypothesis: The purpose was to determine the relationship between symmetry in isometric quadriceps strength and gait biomechanics after return-to-sport training in athletes after ACLR. We hypothesized that as quadriceps strength symmetry increases, athletes will demonstrate more symmetric knee joint biomechanics, including tibiofemoral joint loading during gait., Study Design: Cross-sectional study; Level of evidence, 3., Methods: Of 79 athletes enrolled in the ACL-SPORTS Trial, 76 were participants in this study after completing postoperative rehabilitation and 10 return-to-sport training sessions (mean ± SD, 7.1 ± 2.0 months after ACLR). All participants completed biomechanical walking gait analysis and isometric quadriceps strength assessment using an electromechanical dynamometer. Quadriceps strength was calculated using a limb symmetry index (involved limb value / uninvolved limb value × 100). The biomechanical variables of interest included peak knee flexion angle, peak knee internal extension moment, sagittal plane knee excursion at weight acceptance and midstance, quadriceps muscle force at peak knee flexion angle, and peak medial compartment contact force. Spearman rank correlation (ρ) coefficients were used to determine the relationship between limb symmetry indexes in quadriceps strength and each biomechanical variable; alpha was set to .05., Results: Of the 76 participants, 27 (35%) demonstrated asymmetries in quadriceps strength, defined by quadriceps strength symmetry <90% (n = 23) or >110% (n = 4) (range, 56.9%-131.7%). For the biomechanical variables of interest, 67% demonstrated asymmetry in peak knee flexion angle; 68% and 83% in knee excursion during weight acceptance and midstance, respectively; 74% in internal peak knee extension moment; 57% in medial compartment contact force; and 74% in quadriceps muscle force. There were no significant correlations between quadriceps strength index and limb symmetry indexes for any biomechanical variable after return-to-sport training ( P > .129)., Conclusion: Among those who completed return-to-sport training after ACLR, subsequent quadriceps strength symmetry was not correlated with the persistent asymmetries in gait biomechanics. After a threshold of quadriceps strength is reached, restoring strength alone may not ameliorate gait asymmetries, and current clinical interventions and return-to-sport training may not adequately target gait.
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- 2021
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8. Comparing the Responsiveness of the Global Rating Scale With Legacy Knee Outcome Scores: A Delaware-Oslo Cohort Study.
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Johnson JL, Irrgang JJ, Risberg MA, and Snyder-Mackler L
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- Activities of Daily Living, Adolescent, Adult, Anterior Cruciate Ligament Injuries rehabilitation, Cohort Studies, Humans, Knee Joint surgery, Middle Aged, Patient Reported Outcome Measures, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction rehabilitation
- Abstract
Background: The selection of patient-reported outcome measures (PROMs) is essential for obtaining meaningful information to treat a patient, determine a plan of care, and make clinical decisions; however, the process of selecting PROMs for clinical care is difficult, with the need to balance these multiple factors. Variation makes it difficult to compare data across providers and studies., Hypothesis/purpose: The purpose was to determine the responsiveness of 4 PROMs via effect size and the presence of a ceiling effect in the 5 years after anterior cruciate ligament reconstruction (ACLR). We hypothesized that the single-item Global Rating Scale (GRS) would have an effect size and ceiling effect similar to the commonly used legacy PROMs., Study Design: Cohort study (diagnosis); Level of evidence, 2., Methods: Of the 300 participants, 218 had ACLR, completed postoperative progressive criterion-based rehabilitation early after surgery, and were followed for 5 years. We collected data based on the GRS, the Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS), the International Knee Documentation Committee-Subjective Knee Form (IKDC-SKF), and the KOOS (Knee injury and Osteoarthritis Outcome Score) before and after training and at 6, 12, 24, and 60 months after ACLR., Results: The IKDC-SKF had the largest effect sizes and lowest ceiling effects. The GRS had a similar size and change in both effect size and ceiling effect when compared with the longer PROMs. The GRS and IKDC-SKF had a correlation of 0.72, and the GRS had a minimal detectable change of 2.9 or 4.8, depending on methodology., Conclusion: The GRS responded similarly to the IKDC-SKF, KOS-ADLS, and KOOS and was responsive to patient change. The ease of use and patient-specific nature of the question means that it may be appropriate to use the GRS in clinical care as a consistent measure throughout the course of rehabilitation.
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- 2020
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9. Coper Classification Early After ACL Rupture Changes With Progressive Neuromuscular and Strength Training and Is Associated With 2-Year Success: Response.
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Thoma L, Grindem H, Logerstedt D, Axe M, Engebretsen L, Risberg MA, and Snyder-Mackler L
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- Anterior Cruciate Ligament, Cohort Studies, Delaware, Humans, Rupture, Anterior Cruciate Ligament Injuries, Resistance Training
- Published
- 2019
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10. Coper Classification Early After Anterior Cruciate Ligament Rupture Changes With Progressive Neuromuscular and Strength Training and Is Associated With 2-Year Success: The Delaware-Oslo ACL Cohort Study.
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Thoma LM, Grindem H, Logerstedt D, Axe M, Engebretsen L, Risberg MA, and Snyder-Mackler L
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- Adolescent, Adult, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction, Athletic Injuries surgery, Delaware, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prospective Studies, Rupture classification, Rupture surgery, Rupture therapy, Young Adult, Anterior Cruciate Ligament Injuries classification, Anterior Cruciate Ligament Injuries therapy, Athletic Injuries classification, Athletic Injuries therapy, Resistance Training
- Abstract
Background: Some athletes demonstrate excellent dynamic stability after anterior cruciate ligament (ACL) rupture and return to sport without ACL reconstruction (ACLR) (copers). Others demonstrate persistent instability despite rehabilitation (noncopers) and require surgical stabilization. Testing to determine coper classification can identify potential copers early after rupture. It is unclear how coper classification changes after a brief intervention and how early classification relates to long-term outcomes., Purpose: (1) To evaluate the consistency of early coper classification (potential coper vs noncoper) before and after progressive neuromuscular and strength training (NMST) among athletes early after acute ACL rupture and (2) to evaluate the association of early coper classification with 2-year success after ACL rupture., Study Design: Cohort study; Level of evidence, 2., Methods: This was a prospective analysis from the Delaware-Oslo ACL Cohort Study, composed of athletes consecutively enrolled early after ACL rupture. Participants (n = 271) were tested and classified as potential copers or noncopers according to established criteria before and after a 10-session NMST program. Success 2 years after ACLR or nonoperative rehabilitation was defined as meeting or exceeding sex- and age-matched norms for knee function, no ACL graft rupture, and ≤1 episode of giving way within the previous year. The McNemar test evaluated changes in coper classification pre- to posttraining. Logistic regression adjusted for baseline characteristics was used to evaluate the association of early coper classification and surgical status with 2-year success., Results: Of 300 athletes enrolled, 271 (90%) completed the posttraining data collection, and 219 (73%) returned for the 2-year follow-up. The coper classifications were different between time points: nearly half of those classified initially as noncopers became potential copers ( P < .001). At the 2-year follow-up, 66% of the ACLR group and 74% of the nonoperative group were successful. Athletes who were potential copers posttraining and chose ACLR or nonoperative rehabilitation had 2.7 (95% CI, 1.3-5.6) and 2.9 (95% CI, 1.2-7.2) times the odds of success, respectively, as compared with noncopers who chose ACLR., Conclusion: Coper classification improved after NMST; more athletes became potential copers. Athletes who were potential copers after NMST were more likely to succeed 2 years later regardless of whether they had surgery, strongly supporting the addition of NMST before ACLR. Persistent noncopers fared poorly, indicating that more intensive rehabilitation may be needed.
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- 2019
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11. Functional and Patient-Reported Outcomes Improve Over the Course of Rehabilitation: A Secondary Analysis of the ACL-SPORTS Trial.
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Arundale AJH, Capin JJ, Zarzycki R, Smith A, and Snyder-Mackler L
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- Adolescent, Adult, Female, Humans, Male, Muscle Strength, Plyometric Exercise, Return to Sport, Secondary Prevention, Sex Factors, Single-Blind Method, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction rehabilitation, Exercise Therapy methods, Patient Reported Outcome Measures
- Abstract
Background: The Anterior Cruciate Ligament-Specialized Post-Operative Return to Sports (ACL-SPORTS) randomized controlled trial was designed to address deficits in functional and patient-reported outcomes. The trial examined the effects of a secondary ACL prevention program that included progressive strengthening, agility training, plyometrics (SAP), and other components of current primary prevention protocols, with perturbation training (SAP + PERT group) and without PERT (SAP group). A secondary purpose of this study was to examine whether study outcomes differed between men and women., Hypotheses: (1) Athletes in both the SAP and SAP + PERT groups will have improved knee function and patient-reported outcome measures from pre- to posttraining, (2) the SAP + PERT group would have higher outcome scores than the SAP group, and (3) outcomes will differ by sex., Study Design: Randomized controlled trial (NCT01773317)., Level of Evidence: Level 2., Methods: A total of 79 athletes (39 women) were randomized into the SAP and SAP + PERT groups. All athletes had undergone primary ACL reconstruction and achieved 80% quadriceps strength limb symmetry (QI), full range of motion, had minimal effusion, and had no pain. Additionally, all had begun running again. Prior to and after the training program, athletes' QI, hopping, and patient-reported outcomes were assessed. Repeated-measures analyses of variance were used to determine whether there were differences between groups. Subsequently, the SAP and SAP + PERT groups were collapsed to analyze differences between sexes., Results: There were significant increases for all variables, with the exception of QI. There were no differences between the SAP and SAP + PERT groups. Both men and women made significant improvements in all knee function and patient-reported outcome measures except QI. Men made significant improvements in QI, whereas women did not., Conclusion: The common elements of the training program that all athletes received (10 sessions of progressive strengthening, agility training, plyometrics, and secondary prevention) may be a beneficial addition to the return-to-sport phase of ACL reconstruction rehabilitation. The results suggest that women may require further quadriceps strengthening to maintain and improve QI, an important focus given the relationship between QI and risk for reinjury., Clinical Relevance: During the return-to-sport phase of ACL reconstruction rehabilitation, clinicians tend to shift their focus away from strengthening toward more advanced sports-related tasks. These results indicate that women in particular need continued focus on quadriceps strengthening.
- Published
- 2018
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12. Does Anterior Cruciate Ligament Reconstruction Improve Functional and Radiographic Outcomes Over Nonoperative Management 5 Years After Injury?
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Wellsandt E, Failla MJ, Axe MJ, and Snyder-Mackler L
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- Activities of Daily Living, Adult, Athletes, Cohort Studies, Female, Humans, Male, Middle Aged, Osteoarthritis, Knee epidemiology, Quadriceps Muscle metabolism, Radiography, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods, Knee Joint surgery, Quality of Life
- Abstract
Background: Current practice patterns for the management of anterior cruciate ligament (ACL) injury favor surgical reconstruction. However, long-term outcomes may not differ between patients completing operative and nonoperative treatment of ACL injury. Differences in outcomes between operative and nonoperative treatment of patients in the United States is largely unknown, as are outcomes in long-term strength and performance measures., Purpose: To determine if differences exist in 5-year functional and radiographic outcomes between patients completing operative and nonoperative treatment of ACL injury when both groups complete a progressive criterion-based rehabilitation protocol., Study Design: Cohort study; Level of evidence, 2., Methods: From an original group of 144 athletes, 105 participants (mean ± SD age, 34.3 ± 11.4 years) with an acute ACL rupture completed functional testing (quadriceps strength, single-legged hop, and knee joint effusion testing; patient-reported outcomes) and knee radiographs 5 years after ACL reconstruction or completion of nonoperative rehabilitation., Results: At 5 years, patients treated with ACL reconstruction versus rehabilitation alone did not differ in quadriceps strength ( P = .817); performance on single-legged hop tests ( P = .234-.955); activity level ( P = .349-.400); subjective reports of pain, symptoms, activities of daily living, and knee-related quality of life ( P = .090-.941); or presence of knee osteoarthritis ( P = .102-.978). When compared with patients treated nonoperatively, patients treated operatively did report greater global ratings of knee function ( P = .001), and lower fear ( P = .035) at 5 years but were more likely to possess knee joint effusion ( P = .016)., Conclusion: The current findings indicate that favorable outcomes can occur after both operative and nonoperative management approaches with the use of progressive criterion-based rehabilitation. Further study is needed to determine clinical algorithms for identifying the best candidates for surgical versus nonoperative care after ACL injury. These findings provide an opportunity to improve the educational process between patients and clinicians regarding the expected clinical course and long-term outcomes of operative and nonoperative treatment of ACL injuries.
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- 2018
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13. Do Patients Failing Return-to-Activity Criteria at 6 Months After Anterior Cruciate Ligament Reconstruction Continue Demonstrating Deficits at 2 Years?
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Nawasreh Z, Logerstedt D, Cummer K, Axe MJ, Risberg MA, and Snyder-Mackler L
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- Adolescent, Adult, Athletes, Cohort Studies, Female, Humans, Knee Joint surgery, Male, Movement, Quadriceps Muscle surgery, Sports, Surveys and Questionnaires, Young Adult, Activities of Daily Living, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods
- Abstract
Background: The variability in outcomes after anterior cruciate ligament reconstruction (ACLR) might be related to the criteria that are used to determine athletes' readiness to return to their preinjury activity level. A battery of return-to-activity criteria (RTAC) that emphasize normal knee function and movement symmetry has been instituted to quantitatively determine athletes' readiness to return to preinjury activities., Purpose: To investigate performance-based and patient-reported measures at 12 and 24 months after ACLR between patients who passed or failed RTAC at 6 months after ACLR., Study Design: Cohort study; Level of evidence, 2., Methods: A total of 108 patients who had participated in International Knee Documentation Committee level 1 or 2 sports activities completed RTAC testing at 6, 12, and 24 months after surgery. The RTAC included the isometric quadriceps strength index (QI), 4 single-legged hop tests, the Knee Outcome Survey-activities of daily living subscale (KOS-ADLS), and the global rating scale of perceived function (GRS). Patients who scored ≥90% on all RTAC were classified as the pass group, and those who scored <90% on any RTAC were classified as the fail group. At 12- and 24-month follow-ups, patients were asked if they had returned to the same preinjury activity level., Results: At the 6-month follow-up, there were 48 patients in the pass group and 47 in the fail group. At the 12-month follow-up, 31 patients (73.8%) from the pass group and 15 patients (39.5%) from the fail group passed RTAC, and at the 24-month follow-up, 25 patients (75.8%) from the pass group and 14 patients (51.9%) from the fail group passed RTAC. The rate of return to activities in the pass group was 81% and 84% at 12 and 24 months after ACLR, respectively, compared with only 44% and 46% in the fail group ( P ≤ .012), respectively; however, some patients in the fail group participated in preinjury activities without being cleared by their therapists. At 12 and 24 months, 60.5% and 48.1% of patients continued to fail again on the criteria, respectively. A statistically significant group × time interaction was found for the single hop and 6-m timed hop limb symmetry indices (LSIs) ( P ≤ .037), with only the fail group demonstrating a significant improvement over time. A main effect of group was detected for the QI and the crossover hop and triple hop LSIs ( P < .01), with patients in the pass group demonstrating higher performance. A main effect of time was detected for the crossover hop and triple hop LSIs and the GRS, with improvements seen in both groups ( P < .05)., Conclusion: Patients who passed the RTAC early after ACLR were more likely to demonstrate normal knee function and movement symmetry at 12 and 24 months postoperatively, while patients who failed the RTAC early were more likely to demonstrate impaired knee function and movement asymmetry at 12- and 24-month follow-ups. Patients in the pass group had a higher rate of return to their preinjury activity level compared with those in the fail group. A group of patients chose to return to their preinjury activities, even though they were functionally not ready.
- Published
- 2017
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14. Does Extended Preoperative Rehabilitation Influence Outcomes 2 Years After ACL Reconstruction? A Comparative Effectiveness Study Between the MOON and Delaware-Oslo ACL Cohorts.
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Failla MJ, Logerstedt DS, Grindem H, Axe MJ, Risberg MA, Engebretsen L, Huston LJ, Spindler KP, and Snyder-Mackler L
- Subjects
- Adolescent, Adult, Cohort Studies, Female, Humans, Knee Injuries surgery, Male, Orthopedics, Osteoarthritis, Knee surgery, Sports, Treatment Outcome, Young Adult, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods, Knee Joint surgery
- Abstract
Background: Rehabilitation before anterior cruciate ligament (ACL) reconstruction (ACLR) is effective at improving postoperative outcomes at least in the short term. Less is known about the effects of preoperative rehabilitation on functional outcomes and return-to-sport (RTS) rates 2 years after reconstruction., Purpose/hypothesis: The purpose of this study was to compare functional outcomes 2 years after ACLR in a cohort that underwent additional preoperative rehabilitation, including progressive strengthening and neuromuscular training after impairments were resolved, compared with a nonexperimental cohort. We hypothesized that the cohort treated with extended preoperative rehabilitation would have superior functional outcomes 2 years after ACLR., Study Design: Cohort study; Level of evidence, 3., Methods: This study compared outcomes after an ACL rupture in an international cohort (Delaware-Oslo ACL Cohort [DOC]) treated with extended preoperative rehabilitation, including neuromuscular training, to data from the Multicenter Orthopaedic Outcomes Network (MOON) cohort, which did not undergo extended preoperative rehabilitation. Inclusion and exclusion criteria from the DOC were applied to the MOON database to extract a homogeneous sample for comparison. Patients achieved knee impairment resolution before ACLR, and postoperative rehabilitation followed each cohort's respective criterion-based protocol. Patients completed the International Knee Documentation Committee (IKDC) subjective knee form and Knee injury and Osteoarthritis Outcome Score (KOOS) at enrollment and again 2 years after ACLR. RTS rates were calculated for each cohort at 2 years., Results: After adjusting for baseline IKDC and KOOS scores, the DOC patients showed significant and clinically meaningful differences in IKDC and KOOS scores 2 years after ACLR. There was a significantly higher (P < .001) percentage of DOC patients returning to preinjury sports (72%) compared with those in the MOON cohort (63%)., Conclusion: The cohort treated with additional preoperative rehabilitation consisting of progressive strengthening and neuromuscular training, followed by a criterion-based postoperative rehabilitation program, had greater functional outcomes and RTS rates 2 years after ACLR. Preoperative rehabilitation should be considered as an addition to the standard of care to maximize functional outcomes after ACLR., (© 2016 The Author(s).)
- Published
- 2016
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15. Decreased Knee Joint Loading Associated With Early Knee Osteoarthritis After Anterior Cruciate Ligament Injury.
- Author
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Wellsandt E, Gardinier ES, Manal K, Axe MJ, Buchanan TS, and Snyder-Mackler L
- Subjects
- Adolescent, Adult, Anterior Cruciate Ligament surgery, Biomechanical Phenomena, Case-Control Studies, Electromyography, Female, Gait, Humans, Male, Middle Aged, Walking, Young Adult, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Knee Injuries physiopathology, Knee Injuries surgery, Knee Joint physiopathology, Knee Joint surgery, Osteoarthritis, Knee etiology
- Abstract
Background: Anterior cruciate ligament (ACL) injury predisposes individuals to early-onset knee joint osteoarthritis (OA). Abnormal joint loading is apparent after ACL injury and reconstruction. The relationship between altered joint biomechanics and the development of knee OA is unknown., Hypothesis: Altered knee joint kinetics and medial compartment contact forces initially after injury and reconstruction are associated with radiographic knee OA 5 years after reconstruction., Study Design: Case-control study; Level of evidence, 3., Methods: Individuals with acute, unilateral ACL injury completed gait analysis before (baseline) and after (posttraining) preoperative rehabilitation and at 6 months, 1 year, and 2 years after reconstruction. Surface electromyographic and knee biomechanical data served as inputs to an electromyographically driven musculoskeletal model to estimate knee joint contact forces. Patients completed radiographic testing 5 years after reconstruction. Differences in knee joint kinetics and contact forces were compared between patients with and those without radiographic knee OA., Results: Patients with OA walked with greater frontal plane interlimb differences than those without OA (nonOA) at baseline (peak knee adduction moment difference: 0.00 ± 0.08 N·m/kg·m [nonOA] vs -0.15 ± 0.09 N·m/kg·m [OA], P = .014; peak knee adduction moment impulse difference: -0.001 ± 0.032 N·m·s/kg·m [nonOA] vs -0.048 ± 0.031 N·m·s/kg·m [OA], P = .042). The involved limb knee adduction moment impulse of the group with osteoarthritis was also lower than that of the group without osteoarthritis at baseline (0.087 ± 0.023 N·m·s/kg·m [nonOA] vs 0.049 ± 0.018 N·m·s/kg·m [OA], P = .023). Significant group differences were absent at posttraining but reemerged 6 months after reconstruction (peak knee adduction moment difference: 0.02 ± 0.04 N·m/kg·m [nonOA] vs -0.06 ± 0.11 N·m/kg·m [OA], P = .043). In addition, the OA group walked with lower peak medial compartment contact forces of the involved limb than did the group without OA at 6 months (2.89 ± 0.52 body weight [nonOA] vs 2.10 ± 0.69 body weight [OA], P = .036)., Conclusion: Patients who had radiographic knee OA 5 years after ACL reconstruction walked with lower knee adduction moments and medial compartment joint contact forces than did those patients without OA early after injury and reconstruction., (© 2015 The Author(s).)
- Published
- 2016
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16. Efficacy of the FIFA 11+ Injury Prevention Program in the Collegiate Male Soccer Player.
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Silvers-Granelli H, Mandelbaum B, Adeniji O, Insler S, Bizzini M, Pohlig R, Junge A, Snyder-Mackler L, and Dvorak J
- Subjects
- Adolescent, Athletic Injuries epidemiology, Humans, Male, United States, Universities, Young Adult, Athletes, Athletic Injuries prevention & control, Soccer injuries
- Abstract
Background: The Fédération Internationale de Football Association (FIFA) 11+ program has been shown to be an effective injury prevention program in the female soccer cohort, but there is a paucity of research to demonstrate its efficacy in the male population., Hypothesis: To examine the efficacy of the FIFA 11+ program in men's collegiate United States National Collegiate Athletic Association (NCAA) Division I and Division II soccer., Study Design: Randomized controlled trial; Level of evidence, 1., Methods: Before the commencement of the fall 2012 season, every NCAA Division I and Division II men's collegiate soccer team (N = 396) was solicited to participate in this research study. Human ethics review board approval was obtained through Quorum Review IRB. Sixty-five teams were randomized: 34 to the control group (CG; 850 players) and 31 to the intervention group (IG; 675 players). Four teams in the IG did not complete the study, reducing the number for analysis to 61. The FIFA 11+ injury prevention program served as the intervention and was utilized weekly. Athlete-exposures (AEs), compliance, and injury data were recorded using a secure Internet-based system., Results: In the CG, 665 injuries (mean ± SD, 19.56 ± 11.01) were reported for 34 teams, which corresponded to an incidence rate (IR) of 15.04 injuries per 1000 AEs. In the IG, 285 injuries (mean ± SD, 10.56 ± 3.64) were reported for 27 teams, which corresponded to an IR of 8.09 injuries per 1000 AEs. Total days missed because of injury were significantly higher for the CG (mean ± SD, 13.20 ± 26.6 days) than for the IG (mean ± SD, 10.08 ± 14.68 days) (P = .007). There was no difference for time loss due to injury based on field type (P = .341)., Conclusion: The FIFA 11+ significantly reduced injury rates by 46.1% and decreased time loss to injury by 28.6% in the competitive male collegiate soccer player (rate ratio, 0.54 [95% CI, 0.49-0.59]; P < .0001) (number needed to treat = 2.64)., (© 2015 The Author(s).)
- Published
- 2015
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17. Knee contact force asymmetries in patients who failed return-to-sport readiness criteria 6 months after anterior cruciate ligament reconstruction.
- Author
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Gardinier ES, Di Stasi S, Manal K, Buchanan TS, and Snyder-Mackler L
- Subjects
- Adult, Anterior Cruciate Ligament physiopathology, Athletic Injuries physiopathology, Athletic Injuries surgery, Biomechanical Phenomena physiology, Case-Control Studies, Electromyography, Exercise Test, Female, Gait physiology, Humans, Male, Muscle Contraction physiology, Muscle Strength physiology, Quadriceps Muscle physiology, Rupture, Surveys and Questionnaires, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries, Knee Joint physiopathology
- Abstract
Background: After anterior cruciate ligament (ACL) injury, contact forces are decreased in the injured knee when compared with the uninjured knee. The persistence of contact force asymmetries after ACL reconstruction may increase the risk of reinjury and may play an important role in the development of knee osteoarthritis in these patients. Functional performance may also be useful in identifying patients who demonstrate potentially harmful joint contact force asymmetries after ACL reconstruction., Hypothesis: Knee joint contact force asymmetries would be present during gait after ACL reconstruction, and performance on a specific set of validated return-to-sport (RTS) readiness criteria would discriminate between those who demonstrated contact force asymmetries and those who did not., Study Design: Descriptive laboratory study., Methods: A total of 29 patients with ACL ruptures participated in gait analysis and RTS readiness testing 6 months after reconstruction. Muscle and joint contact forces were estimated using an electromyography (EMG)-driven musculoskeletal model of the knee. The magnitude of typical limb asymmetry in uninjured controls was used to define limits of meaningful limb asymmetry in patients after ACL reconstruction. The RTS testing included isometric quadriceps strength testing, 4 unilateral hop tests, and 2 self-report questionnaires. Paired t tests were used to assess limb symmetry for peak medial and tibiofemoral contact forces in all patients, and a mixed-design analysis of variance was used to analyze the effect of passing or failing RTS testing on contact force asymmetry., Results: Among all patients, neither statistically significant nor meaningful contact force asymmetries were identified. However, patients who failed RTS testing exhibited meaningful contact force asymmetries, with tibiofemoral contact force being significantly lower for the involved knee. Conversely, patients who passed RTS testing exhibited neither significant nor meaningful contact force asymmetries., Conclusion: Joint contact force asymmetries during gait are present in some patients 6 months after ACL reconstruction. Patients who demonstrated poor functional performance on RTS readiness testing exhibited significant and meaningful contact force asymmetries., Clinical Relevance: When assessing all patients together, variability in the functional status obscured significant and meaningful differences in contact force asymmetry in patients 6 months after ACL reconstruction. These specific RTS readiness criteria appear to differentiate between those who demonstrate joint contact force symmetry after ACL reconstruction and those who do not., (© 2014 The Author(s).)
- Published
- 2014
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18. Gait patterns differ between ACL-reconstructed athletes who pass return-to-sport criteria and those who fail.
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Di Stasi SL, Logerstedt D, Gardinier ES, and Snyder-Mackler L
- Subjects
- Adaptation, Physiological, Adolescent, Adult, Analysis of Variance, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries, Biomechanical Phenomena, Exercise Test, Female, Humans, Joint Instability physiopathology, Male, Muscle Strength, Quadriceps Muscle physiology, Young Adult, Anterior Cruciate Ligament Reconstruction, Gait physiology, Hip physiopathology, Knee physiopathology, Knee Joint physiopathology, Recovery of Function
- Abstract
Background: The current standard of practice for an athlete to return to sport after anterior cruciate ligament (ACL) reconstruction is varied. Attempt to return to activity is typically advised 6 months after surgery, but functional performance deficits and gait abnormalities are often still evident and may have important implications on future function., Hypothesis: When comparing the involved and uninvolved limbs, patients who failed return-to-sport (RTS) criteria would demonstrate (1) smaller peak knee angles, extensor moments, and peak power absorption at the knee of the involved limb and (2) larger peak hip angles, extensor moments, and peak power generation of the involved limb., Study Design: Controlled laboratory study., Methods: A total of 42 patients completed functional and biomechanical gait assessment 6 months after ACL reconstruction. Functional testing involved an isometric quadriceps strength test, 4 single-legged hop tests, and 2 self-report questionnaires. Three-dimensional motion analysis was used to measure sagittal plane kinematics and kinetics of the hip and knee. A mixed-model analysis of variance and post hoc t tests were used to compare the limb symmetry of those who passed and those who did not pass RTS criteria. Minimal clinically important differences were calculated from healthy gait data and used to further define meaningful limb asymmetries., Results: Twenty of the 42 (48%) patients passed RTS criteria 6 months after ACL reconstruction. Patients who did not pass the criteria demonstrated statistically significant differences between limbs on all kinematic and kinetic variables at the knee (P ≤ .027). Clinically meaningful asymmetries at the hip were also identified in this group. Only kinetic asymmetries at the knee were identified in the patients who passed RTS criteria., Conclusion: Athletes who demonstrate superior functional performance 6 months after ACL reconstruction may have fewer abnormal and asymmetrical gait behaviors than their poorer performing counterparts. Patients who did not pass RTS criteria not only demonstrated larger kinematic and kinetic asymmetries between limbs but also appeared to use a gait strategy more closely aligned with athletes early after ACL rupture., Clinical Relevance: Poor performance on a battery of functional performance measures may be related to the presence of movement asymmetries in athletes after ACL reconstruction. Objective RTS criteria have the potential to provide information to clinicians who determine when these athletes return to activity, and may aid in the prescription of targeted rehabilitation to address underlying movement asymmetry.
- Published
- 2013
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19. A pair-matched comparison of return to pivoting sports at 1 year in anterior cruciate ligament-injured patients after a nonoperative versus an operative treatment course.
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Grindem H, Eitzen I, Moksnes H, Snyder-Mackler L, and Risberg MA
- Subjects
- Adult, Anterior Cruciate Ligament surgery, Athletic Injuries surgery, Cohort Studies, Female, Humans, Male, Return to Work, Anterior Cruciate Ligament Injuries, Athletic Injuries therapy
- Abstract
Background: Patients usually return to pivoting sports between 6 months and 1 year after anterior cruciate ligament (ACL) reconstruction, but no matched study has so far examined 1-year return to sport rates in nonoperatively and operatively treated ACL-injured patients., Hypothesis: Anterior cruciate ligament-injured patients following a nonoperative treatment course, including recommendation of activity modification, will have lower return to pivoting sport rates than operatively treated patients 1 year after baseline testing/surgery, when matched by preinjury sports activity, age, and sex., Study Design: Cohort study; level of evidence, 3., Methods: Sixty-nine nonoperatively treated ACL-injured patients were pair-matched with 69 operatively treated patients (n = 138), based on specific preinjury sport, age, and sex. Nonoperatively treated patients were recommended not to return to level I sports. Patients were defined as nonoperatively or operatively treated according to their status at follow-up. The baseline and follow-up testing included registration of sports participation, KT-1000 arthrometer measurements, 4 hop tests, and patient-reported outcome measures. McNemars test and paired t tests or Wilcoxon test were used to compare outcomes of nonoperatively and operatively treated patients., Results: No significant baseline differences were found. At 12.9 ± 1.2 months (mean ± standard deviation) after baseline testing (nonoperative) and 12.7 ± 1.2 months after surgery (operative), there was no significant difference in overall return to sport rates (nonoperative: 68.1%, operative: 68.1%, P = 1.00), or in return to level I sport rates (nonoperative: 54.8%, operative: 61.9%, P = .66). Nonoperatively treated patients who participated in level I sports before injury had a significantly lower return to sport rate (54.8%) than nonoperatively treated patients who participated in level II sports (88.9%, P = .003). The nonoperatively treated patients had significantly higher knee joint laxity, but significantly better hop test limb symmetry indexes, Knee Outcome Survey Activities of Daily Living scores, and International Knee Documentation Committee Subjective Knee Form 2000 scores. None of the functional differences was larger than the smallest detectable difference., Conclusion: Anterior cruciate ligament-injured patients following a nonoperative treatment course, including recommendations of activity modifications, and operatively treated patients did not have significantly different rates of returning to pivoting sports after 1 year in this pair-matched cohort study. Clinicians should be aware of a potentially high level of noncompliance to recommendations of activity modifications. Although these results show that it is possible for nonoperatively treated patients to return to sport after rehabilitation, future follow-ups are needed to examine whether these patients maintain sports participation over time, and what long-term consequences they may suffer regarding subsequent injuries and knee osteoarthritis.
- Published
- 2012
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20. Single-legged hop tests as predictors of self-reported knee function after anterior cruciate ligament reconstruction: the Delaware-Oslo ACL cohort study.
- Author
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Logerstedt D, Grindem H, Lynch A, Eitzen I, Engebretsen L, Risberg MA, Axe MJ, and Snyder-Mackler L
- Subjects
- Adult, Cohort Studies, Female, Humans, Knee Injuries rehabilitation, Knee Injuries surgery, Male, Middle Aged, Prognosis, Recovery of Function, Treatment Outcome, Young Adult, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Reconstruction, Exercise Test, Knee Injuries diagnosis
- Abstract
Background: Single-legged hop tests are commonly used functional performance measures that can capture limb asymmetries in patients after anterior cruciate ligament (ACL) reconstruction. Hop tests hold potential as predictive factors of self-reported knee function in individuals after ACL reconstruction., Hypothesis: Single-legged hop tests conducted preoperatively would not and 6 months after ACL reconstruction would predict self-reported knee function (International Knee Documentation Committee [IKDC] 2000) 1 year after ACL reconstruction., Study Design: Cohort study (prognosis); Level of evidence, 2., Methods: One hundred twenty patients who were treated with ACL reconstruction performed 4 single-legged hop tests preoperatively and 6 months after ACL reconstruction. Self-reported knee function within normal ranges was defined as IKDC 2000 scores greater than or equal to the age- and sex-specific normative 15th percentile score 1 year after surgery. Logistic regression analyses were performed to identify predictors of self-reported knee function within normal ranges. The area under the curve (AUC) from receiver operating characteristic curves was used as a measure of discriminative accuracy., Results: Eighty-five patients completed single-legged hop tests 6 months after surgery and the 1-year follow-up with 68 patients classified as having self-reported knee function within normal ranges 1 year after reconstruction. The crossover hop and 6-m timed hop limb symmetry index (LSI) 6 months after ACL reconstruction were the strongest individual predictors of self-reported knee function (odds ratio, 1.09 and 1.10) and the only 2 tests in which the confidence intervals of the discriminatory accuracy (AUC) were above 0.5 (AUC = 0.68). Patients with knee function below normal ranges were over 5 times more likely of having a 6-m timed hop LSI lower than the 88% cutoff than those with knee function within normal ranges. Patients with knee function within normal ranges were 4 times more likely to have a crossover hop LSI greater than the 95% cutoff than those with knee function below normal ranges. No preoperative single-legged hop test predicted self-reported knee function within normal ranges 1 year after ACL reconstruction (all P > .353)., Conclusion: Single-legged hop tests conducted 6 months after ACL reconstruction can predict the likelihood of successful and unsuccessful outcome 1 year after ACL reconstruction. Patients demonstrating less than the 88% cutoff score on the 6-m timed hop test at 6 months may benefit from targeted training to improve limb symmetry in an attempt to normalize function. Patients with minimal side-to-side differences on the crossover hop test at 6 months possibly will have good knee function at 1 year if they continue with their current training regimen. Preoperative single-legged hop tests are not able to predict postoperative outcomes.
- Published
- 2012
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21. Muscle impairments in patients with knee osteoarthritis.
- Author
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Alnahdi AH, Zeni JA, and Snyder-Mackler L
- Abstract
Context: Muscle impairments associated with knee osteoarthritis (OA) are the primary underlying cause of functional limitations. Understanding the extent of muscle impairments, its relationship with physical function and disease progression, and the evidence behind exercise therapy that targets muscle impairments is crucial., Evidence Acquisition: An electronic search for relevant articles using MEDLINE and CINHAL databases up to September 2011 was performed. In addition to the electronic search, retrieved articles were searched manually for relevant studies., Results: Quadriceps, hamstrings, and hip muscles are significantly impaired in subjects with knee OA compared with age-matched controls. Muscle strength, especially quadriceps, is a major determinant of both performance-based and self-reported physical function. Whether stronger quadriceps is protective against knee OA onset and progression is not clear. Exercise therapy, including global and targeted resistance training, is effective in reducing pain and improving function in subjects with knee OA., Conclusions: Subjects with knee OA have significant muscle impairments. These muscle impairments affect physical function and should be targeted in therapy. Further research is needed to explore the relationship between quadriceps strength and knee OA initiation and progression and to determine the optimal exercise prescription that augments outcomes in this patient population.
- Published
- 2012
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22. Clinical Outcomes and Return-to-Sports Participation of 50 Soccer Players After Anterior Cruciate Ligament Reconstruction Through a Sport-Specific Rehabilitation Protocol.
- Author
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Della Villa S, Boldrini L, Ricci M, Danelon F, Snyder-Mackler L, Nanni G, and Roi GS
- Abstract
Background: Rehabilitation of soccer players after anterior cruciate ligament reconstruction is usually performed without sport-specific guidelines, and the final phases are often left to the team coaches. The possibility of changing this approach has not yet been investigated., Study Design: Case series., Hypothesis: A specific rehabilitation protocol for soccer players, with direct control of the last on-field rehabilitation phases, may lead to complete functional recovery., Methods: Fifty competitive soccer players who followed a sport-specific rehabilitation protocol for soccer were evaluated during the recovery period until their return to competition. The assessment of the functional outcomes was performed using the Knee Outcome Survey-Sports Activity Scale and isokinetic and aerobic fitness tests., Results: The average start of on-field rehabilitation was 90 ± 26 days after surgery; the average time to return to the competitions was 185 ± 52 days. The improvement in the Knee Outcome Survey-Sports Activity Scale during on-field rehabilitation was significant (P < 0.01; from 79 ± 15% to 96 ± 7%). The isokinetic and aerobic fitness tests showed a significant improvement of muscle strength (knee extensors, +55%, P < 0.01; knee flexors, +86%, P < 0.01) and aerobic threshold (+23%, P < 0.01) from the beginning to the end of on-field rehabilitation., Conclusions: Adding on-field rehabilitation to the traditional protocols after anterior cruciate ligament reconstruction may safely lead to complete functional recovery in soccer players.
- Published
- 2012
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23. Single-legged hop tests as predictors of self-reported knee function in nonoperatively treated individuals with anterior cruciate ligament injury.
- Author
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Grindem H, Logerstedt D, Eitzen I, Moksnes H, Axe MJ, Snyder-Mackler L, Engebretsen L, and Risberg MA
- Subjects
- Adolescent, Adult, Cohort Studies, Female, Humans, Knee Injuries therapy, Male, Middle Aged, Prognosis, Prospective Studies, ROC Curve, Treatment Outcome, Young Adult, Anterior Cruciate Ligament Injuries, Exercise Test methods, Knee physiology
- Abstract
Background: Previous studies have found significant predictors for functional outcome after anterior cruciate ligament (ACL) reconstruction; however, studies examining predictors for functional outcome in nonoperatively treated individuals are lacking., Hypothesis: Single-legged hop tests predict self-reported knee function (International Knee Documentation Committee [IKDC] 2000) in nonoperatively treated ACL-injured individuals 1 year after baseline testing., Study Design: Cohort study (prognosis); Level of evidence, 2., Methods: Ninety-one nonoperatively treated patients with an ACL injury were tested using 4 single-legged hop tests on average 74 ± 30 days after injury in a prospective cohort study. Eighty-one patients (89%) completed the IKDC 2000 1 year later. Patients with an IKDC 2000 score equal to or higher than the age- and gender-specific 15th percentile score from previously published data on an uninjured population were classified as having self-reported function within normal ranges. Logistic regression analyses were performed to identify predictors of self-reported knee function. The area under the curve (AUC) from receiver operating characteristic curves was used as a measure of discriminative accuracy. Optimal limb symmetry index (LSI) cutoff for the best single-legged hop test was defined as the LSI with the highest product of sensitivity and specificity., Results: Single hop for distance symmetry indexes predicted self-reported knee function at the 1-year follow-up (P = .036). Combinations of any 2 hop tests (AUC = 0.64-0.71) did not give a higher discriminative accuracy than the single hop alone (AUC = 0.71). A cutoff of 88% (LSI) for the single hop revealed a sensitivity of 71.4% and a specificity of 71.7%., Conclusion: The single hop for distance (LSI) significantly predicted self-reported knee function after 1 year in nonoperatively treated ACL-injured patients. Combinations of 2 single-legged hop tests did not lead to higher discriminative accuracy than the single hop alone.
- Published
- 2011
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24. Anterior cruciate ligament-deficient potential copers and noncopers reveal different isokinetic quadriceps strength profiles in the early stage after injury.
- Author
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Eitzen I, Eitzen TJ, Holm I, Snyder-Mackler L, and Risberg MA
- Subjects
- Adolescent, Adult, Anterior Cruciate Ligament physiopathology, Cross-Sectional Studies, Female, Humans, Knee Injuries physiopathology, Male, Middle Aged, Torque, Young Adult, Anterior Cruciate Ligament Injuries, Knee Injuries rehabilitation, Quadriceps Muscle physiopathology
- Abstract
Background: Isokinetic muscle strength testing using the peak torque value is the most frequently included quadriceps muscle strength measurement for anterior cruciate ligament (ACL)-injured subjects. PURPOSE AND HYPOTHESES: The purpose of this study was to investigate quadriceps muscle performance during the whole isokinetic curve in subjects with ACL deficiency classified as potential copers or noncopers and to investigate whether these curve profiles were associated with single-legged hop performance. We hypothesized that quadriceps muscle torque at other knee flexion angles than peak torque would give more information about quadriceps muscle strength deficits. Furthermore, we hypothesized that there would be significant torque differences between potential copers and noncopers and a significant relationship between angle-specific torque values and single-legged hop performance., Study Design: Cross-sectional study; Level of evidence, 3., Methods: Seventy-six individuals with a complete unilateral ACL rupture within the last 3 months were included. The subjects were classified as potential copers and noncopers. Isokinetic quadriceps muscle tests were performed at 60 deg/s. Mean torque values were calculated for peak torque as well as for specific knee flexion angles. The 1-legged hop and the 6-m timed hop tests were included, and symmetry indices were used., Results: The peak torque value did not identify the largest quadriceps muscle strength deficit. Rather, these were established at knee flexion angles of less than 40 degrees . There were significant differences in angle-specific torque values between potential copers and noncopers (P < .05). Moderate to strong associations were disclosed between angle-specific torque values and single-legged hop performance, but only for noncopers (r > or = .32-.58)., Conclusion: Angle-specific quadriceps muscle torque values of less than 40 degrees of knee flexion provide more information on the quadriceps strength deficits after ACL injury than the commonly used peak torque values. Interpretation of the isokinetic curve profiles seems to be of clinical importance for the evaluation of quadriceps muscle performance after ACL injury.
- Published
- 2010
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25. Data-based interval hitting program for female college volleyball players.
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Hurd W, Hunter-Giordano A, Axe M, and Snyder-Mackler L
- Abstract
Context: Interval sports programs are a critical rehabilitation element when preparing the injured athlete for a return to preinjury activities. There is currently no published interval hitting program to guide a return to unrestricted play for the volleyball athlete. Therefore, data-based, position-specific overhead hitting programs that control for intensity, time, and number of ball strikes were developed for female college volleyball players., Evidence Acquisition: Records from a single Division I varsity women's volleyball team were examined for all matches during 7 consecutive years of team play. Data were collected for number of hitting and service attempts per game for each position and the number of games per match., Results: Per game, middle hitters averaged 4.51 attacks and 2.77 service attempts; right-side hitters, 3.58 attacks and 1.26 service attempts; outside hitters, 6.37 attacks and 3.44 service attempts; and setters and defensive specialists, 0.17 attacks and 1.78 service attempts., Conclusion: The interval hitting program can provide rehabilitation specialists with a data-based approach that may facilitate a return to play and minimize the risk of reinjury for volleyball athletes.
- Published
- 2009
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26. Data-based interval throwing programs for baseball players.
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Axe M, Hurd W, and Snyder-Mackler L
- Abstract
Context: Baseball throwing injuries are common. Emphasis on injury prevention and rehabilitation is made in an attempt to keep athletes on the field of competition. Interval throwing programs are an integral part of training, conditioning, and returning an injured baseball player to the game., Evidence Acquisition: Development of data-driven programs was based on the number, type, distance, and intensity of throws during games, across the spectrum of ages and positions for baseball athletes at all levels of play. Statistical analysis by age, position, and level of play determined the need for separate throwing programs. Means, the high range, game rules, and practical considerations were used to develop each data-based interval throwing program., Results: Data-based age and level-of-play interval throwing programs for pitchers, catchers, infielders, and outfielders have been developed, tested, and implemented for more than 10 years. Progression is based on type and location of injury, symptoms in response to throwing, and preinjury performance profile. Although the throwing programs are highly structured, there is ample opportunity to modify them to meet the needs of individual athletes., Conclusion: Data-based interval throwing programs for baseball athletes are an integral training and conditioning element for both injured and uninjured athletes who are preparing for sports participation. Medical team members should equip themselves with an understanding of how to use the programs for safe training, conditioning, and return to play.
- Published
- 2009
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27. Management of the athlete with acute anterior cruciate ligament deficiency.
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Hurd W, Axe M, and Snyder-Mackler L
- Abstract
Background: Identification of highly active individuals early after acute anterior cruciate ligament deficiency who are good candidates for nonoperative management is a clinical challenge. The University of Delaware has developed and validated a treatment algorithm and screening examination to distinguish between nonoperative and surgical candidates., Study Design: Review., Evidence Acquisition: A description of the decision-making rules and rehabilitation protocol for highly active individuals with anterior cruciate ligament deficiency is provided. Results from clinical trials, outcome studies, and biomechanical investigations conducted using the treatment algorithm and screening examination are also reviewed., Results: Patients identified as nonoperative rehabilitation candidates using these clinical guidelines have a far greater success rate than what has been reported when patients self-select nonoperative management. Furthermore, nonoperative outcomes are improved when patients participate in a perturbation-enhanced rehabilitation protocol. Divergent lower extremity movement patterns are consistent with the different functional abilities of the dichotomous patient groups identified with the screening examination., Conclusion: Given the differential patient response to anterior cruciate ligament injury, implementation of the decision-making guidelines discussed in this review offers clinicians the opportunity to provide individualized patient care rather than continuing with a blanket surgical treatment strategy.
- Published
- 2009
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28. A 10-year prospective trial of a patient management algorithm and screening examination for highly active individuals with anterior cruciate ligament injury: Part 1, outcomes.
- Author
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Hurd WJ, Axe MJ, and Snyder-Mackler L
- Subjects
- Adolescent, Adult, Algorithms, Anterior Cruciate Ligament physiology, Decision Making, Female, Humans, Knee Injuries classification, Knee Injuries rehabilitation, Male, Middle Aged, Physical Examination, Prospective Studies, Recovery of Function physiology, Treatment Outcome, Anterior Cruciate Ligament Injuries, Knee Injuries therapy
- Abstract
Background: A treatment algorithm and screening examination have been developed to guide patient management and prospectively determine potential for highly active individuals to succeed with nonoperative care after anterior cruciate ligament rupture., Objective: To prospectively characterize and classify the entire population of highly active individuals over a 10-year period and provide final outcomes for individuals who elected nonoperative care., Methods: Inclusion criteria included presentation within 7 months of the index injury and an International Knee Documentation Committee level I or II activity level before injury. Concomitant injury, unresolved impairments, and a screening examination were used as criteria to guide management and classify individuals as noncopers (poor potential) or potential copers (good potential) for nonoperative care., Results: A total of 832 highly active patients with subacute anterior cruciate ligament tears were seen over the 10-year period; 315 had concomitant injuries, 87 had unresolved impairments, and 85 did not participate in the classification algorithm. The remaining 345 patients (216 men, 129 women) participated in the screening examination a mean of 6 weeks after the index injury. There were 199 subjects classified as noncopers and 146 as potential copers. Sixty-three of 88 potential copers successfully returned to preinjury activities without surgery, with 25 of these patients not undergoing anterior cruciate ligament reconstruction at the time of follow-up., Conclusion: The classification algorithm is an effective tool for prospectively identifying individuals early after anterior cruciate ligament injury who want to pursue nonoperative care or must delay surgical intervention and have good potential to do so.
- Published
- 2008
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29. A 10-year prospective trial of a patient management algorithm and screening examination for highly active individuals with anterior cruciate ligament injury: Part 2, determinants of dynamic knee stability.
- Author
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Hurd WJ, Axe MJ, and Snyder-Mackler L
- Subjects
- Adolescent, Adult, Algorithms, Anterior Cruciate Ligament physiology, Decision Making, Female, Humans, Knee Injuries classification, Knee Injuries rehabilitation, Male, Physical Examination, Prospective Studies, Anterior Cruciate Ligament Injuries, Joint Instability physiopathology, Knee Injuries therapy, Knee Joint physiology
- Abstract
Objective: To clarify the determinants of dynamic knee stability early after anterior cruciate ligament injury., Study Design: Cohort study (diagnosis); Level of evidence, 1., Methods: Three hundred forty-five consecutive patients who were regular participants in International Knee Documentation Committee level I/II sports before injury and had an acute isolated anterior cruciate ligament injury from the practice of a single orthopaedic surgeon underwent a screening examination including clinical measures, knee laxity, quadriceps strength, hop testing, and patient self-reported knee function a mean of 6 weeks after injury when impairments were resolved. Independent t tests were performed to evaluate differences in quadriceps strength and anterior knee laxity between potential copers and noncopers. Hierarchical regression was performed to determine the influence of quadriceps strength, preinjury activity level, and anterior knee laxity on hop test performance, as well as the influence of timed hop, crossover hop, quadriceps strength, preinjury activity level, and anterior knee laxity on self-assessed global function., Results: Neither anterior knee laxity nor quadriceps strength differed between potential copers and noncopers. Quadriceps strength influenced hop test performance more significantly than did preinjury activity level or anterior knee laxity, but the variance accounted for by quadriceps strength was low (range, 4%-8%). Timed hop performance was the only variable that affected self-assessed global function., Conclusion: Traditional surgical decision making based on passive anterior knee laxity and preinjury activity level is not supported by the results, as neither is a good predictor of dynamic knee stability. A battery of clinical tests that capture neuromuscular adaptations, including the timed hop test, may be useful in predicting function and guiding individualized patient management after anterior cruciate ligament injury.
- Published
- 2008
- Full Text
- View/download PDF
30. The drop-jump screening test: difference in lower limb control by gender and effect of neuromuscular training in female athletes.
- Author
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Hewett T, Snyder-Mackler L, and Spindler KP
- Subjects
- Adolescent, Ankle Joint physiology, Biomechanical Phenomena, Child, Female, Hip Joint physiology, Humans, Male, Muscle, Skeletal physiology, Task Performance and Analysis, Video Recording, Exercise physiology, Knee Joint physiology, Leg physiology
- Published
- 2007
- Full Text
- View/download PDF
31. Quadriceps weakness, atrophy, and activation failure in predicted noncopers after anterior cruciate ligament injury.
- Author
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Williams GN, Buchanan TS, Barrance PJ, Axe MJ, and Snyder-Mackler L
- Subjects
- Adolescent, Adult, Athletic Injuries rehabilitation, Athletic Injuries surgery, Atrophy, Cross-Sectional Studies, Female, Humans, Leg physiology, Magnetic Resonance Imaging, Male, Middle Aged, Prognosis, Treatment Outcome, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries, Muscle Weakness, Muscle, Skeletal pathology, Muscle, Skeletal physiology
- Abstract
Background: Quadriceps weakness is common after anterior cruciate ligament injury, especially in those who do not compensate well for the injury ("noncopers"). Both atrophy and activation failure have been demonstrated in this population but have not been directly related to quadriceps weakness., Hypotheses: (1) Quadriceps strength, volumes, and cross-sectional areas of the noncopers would be smaller than those of the contralateral muscles, whereas other muscles would not demonstrate atrophy. (2) Quadriceps muscle activation deficits would be observed. (3) Atrophy and activation failure would account for the quadriceps weakness in these patients., Study Design: Cross-sectional study, Level of evidence, 3., Methods: Seventeen noncopers with isolated anterior cruciate ligament injury underwent burst-superimposition strength and activation testing of the quadriceps and magnetic resonance imaging of 12 muscles an average of 2 months after injury. Morphological characteristics was described by digitally reconstructing each muscle from the axial images and calculating muscle volume and peak cross-sectional area., Results: The quadriceps muscles of the anterior cruciate ligament-deficient limb were significantly weaker (average 25%) than those of the uninjured side; activation failure (8%-10%) was observed for the quadriceps muscles of both limbs. The total quadriceps, vastus lateralis, and vastus intermedius volume and cross-sectional area were significantly smaller in the anterior cruciate ligament-deficient limb. There was no significant atrophy of any other muscle or muscle group. Atrophy and activation failure explained more than 60% of the variance in quadriceps weakness (P = .004)., Conclusion: The quadriceps femoris weakens soon after acute anterior cruciate ligament injury. Activation deficits and atrophy occur and affect quadriceps strength. Rehabilitation techniques that address activation deficits as well as atrophy may be necessary to restore quadriceps strength.
- Published
- 2005
- Full Text
- View/download PDF
32. Upper extremity weight-training modifications for the injured athlete. A clinical perspective.
- Author
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Fees M, Decker T, Snyder-Mackler L, and Axe MJ
- Subjects
- Adaptation, Physiological, Hand physiology, Hand Strength physiology, Humans, Joint Instability rehabilitation, Muscle Contraction physiology, Muscle, Skeletal physiology, Posture physiology, Range of Motion, Articular physiology, Rotator Cuff physiopathology, Rotator Cuff Injuries, Shoulder Impingement Syndrome rehabilitation, Shoulder Joint physiopathology, Arm physiology, Athletic Injuries rehabilitation, Shoulder Injuries, Weight Lifting education, Weight Lifting physiology
- Abstract
The ability of the health care professional to make correct decisions about the progression of weight-training is critical to the rehabilitation process. The purpose of this article is to describe our approach to modification of weight-lifting techniques using the injured shoulder as a model. Additionally, the impact of various upper extremity weight-training techniques on healthy athletes is discussed. The effects of grip, hand spacing, bar trajectory, and start and finishing positions on microtraumatic injury and return to weight-training activities after injury are considered. Several weight-training functional progressions for common multijoint exercises (such as bench press, shoulder press, power clean) are presented. Adaptations for periodization are also presented for implementation in the rehabilitation sequence. The weight-training modifications described in this paper will assist the health professional to safely return athletes to the weight room after shoulder injury.
- Published
- 1998
- Full Text
- View/download PDF
33. The relationship between passive joint laxity and functional outcome after anterior cruciate ligament injury.
- Author
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Snyder-Mackler L, Fitzgerald GK, Bartolozzi AR 3rd, and Ciccotti MG
- Subjects
- Adolescent, Adult, Anterior Cruciate Ligament physiopathology, Humans, Middle Aged, Rupture physiopathology, Treatment Outcome, Anterior Cruciate Ligament Injuries, Joint Instability physiopathology, Knee Injuries physiopathology, Knee Joint physiopathology
- Abstract
Twenty patients with anterior cruciate ligament-deficient knees were studied. Ten patients returned to all sports activities (compensators) and 10 patients were not improved with nonoperative management and required surgical stabilization (noncompensators). Joint laxity was measured using a KT-2000 arthrometer (manual maximum Lachman). Subjects completed a Lysholm questionnaire and Knee Outcome Score. The International Knee Documentation Committee form was also completed. Patients also rated their knee function on a scale of 1 to 100. There was no difference in level and frequency of athletic activity between the two groups before their anterior cruciate ligament injuries as determined by the knee outcome score. The compensator group had a mean side-to-side difference of 3.25 mm at 89 N and the noncompensators had a mean difference of 3 mm preoperatively. Manual maximum tests gave side-to-side differences of 6.7 mm for the compensators and 6 mm for the noncompensators. There were no differences in laxity measures between groups. The correlation between knee outcome scores and side-to-side laxity measurements were not significant. Measurements of anterior laxity in anterior cruciate ligament-deficient patients were not correlated with measures of functional outcome used in this study. Functional outcome measurements that are partially based on joint laxity measures, such as the International Knee Documentation Committee form, may artificially overestimate the disability after anterior cruciate ligament rupture.
- Published
- 1997
- Full Text
- View/download PDF
34. Development of a distance-based interval throwing program for Little League-aged athletes.
- Author
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Axe MJ, Snyder-Mackler L, Konin JG, and Strube MJ
- Subjects
- Adolescent, Age Factors, Arm physiology, Athletic Injuries prevention & control, Athletic Injuries rehabilitation, Baseball injuries, Baseball physiology, Child, Forecasting, Humans, Male, Models, Biological, Muscle Contraction physiology, Muscle, Skeletal physiology, Physical Endurance physiology, Reproducibility of Results, Safety, Baseball education, Program Development
- Abstract
We developed a distance-based interval throwing program for Little League-aged athletes (9 to 12 years) to be used in training and rehabilitation. The timing and repetition parameters were developed from data collected during 400 innings of organized baseball during a single season, and short toss distance from Little League rules for field dimensions. There were 1022 boys from organized baseball teams in the four studies. Maximal distance and speed measurements were recorded for 853 boys. We developed a mathematical model from these data to predict maximal throwing distance from maximal throwing speed. This model was then tested on a second sample of 114 players. We compared the predicted distance with the actual maximal throwing distance; the correlation coefficient was 0.92. Forty players aged 9 to 12 participated in a study to assess degradation of speed and distance. The average variability of the speed was small (< 5 mph), but the variability in distance was large (22.4 feet). Fifteen boys then threw the entire throwing program as designed. These results show that healthy young athletes can be expected to be able to throw the predicted value of this practical progressive interval throwing program for Little League-aged athletes. The appropriate program can be assigned from age and known preinjury pitch speed.
- Published
- 1996
- Full Text
- View/download PDF
35. Fate of the ACL-injured patient: a prospective outcome study.
- Author
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Snyder-Mackler L
- Subjects
- Anterior Cruciate Ligament surgery, Humans, Prospective Studies, Treatment Outcome, Anterior Cruciate Ligament Injuries, Athletic Injuries surgery, Knee Injuries surgery, Postoperative Complications etiology
- Published
- 1995
- Full Text
- View/download PDF
36. Effect of standard and Aircast tennis elbow bands on integrated electromyography of forearm extensor musculature proximal to the bands.
- Author
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Snyder-Mackler L and Epler M
- Subjects
- Adult, Evaluation Studies as Topic, Humans, Orthotic Devices, Tennis Elbow physiopathology, Braces, Electromyography methods, Muscles physiopathology, Tennis Elbow therapy
- Abstract
Classic tennis elbow, or lateral epicondylitis, has been described as an overuse or misuse injury resulting in a tendinitis. The extensor carpi radialis brevis (ECRB) and extensor digitorum communis (EDC) have been implicated as primary culprits in this pathology. Tennis elbow has been treated using a constrictive band placed several centimeters distal to the origin of these two muscles. Aircast (Aircast Inc., Summit, NJ) has developed a new style of band that employs an air-filled bladder as the counterpressure element. This study tested the effect of both standard and Aircast bands on EMG activity of the EDC and ECRB proximal to the band compared to control values. Ten normal subjects, ranging in age from 20 to 43 years, were tested. Right upper extremities were tested in all cases. The subjects' forearms were stabilized in the CYBEX II forearm stabilization V-pad. The ECRB and EDC were then impaled with monopolar EMG needle electrodes. The CYBEX data were recorded using the HUMAC system and the EMG data were recorded and analyzed using the Cadwell 7400. EMG data were recorded at 80% of maximum voluntary isometric contraction (MVIC) with no band, the standard band, and the Aircast band. An analysis of variance (ANOVA) with repeated measures of integrated EMG (IEMG) and Duncan's multiple comparison tests revealed that the Aircast caused a significant reduction in IEMG of the ECRB and EDC when compared with control values and the standard band. The decrease in IEMG with the standard band was not statistically significant.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1989
- Full Text
- View/download PDF
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