29 results on '"Samara, S"'
Search Results
2. Fixed-time traffic signal optimization using a multi-objective evolutionary algorithm and microsimulation of urban networks
- Author
-
Costa, Breno C, primary, Leal, Samara S, additional, Almeida, Paulo EM, additional, and Carrano, Eduardo G, additional
- Published
- 2016
- Full Text
- View/download PDF
3. Bridging Liberalism and Multiculturalism in American Education
- Author
-
Samara S. Foster, Kenneth R. Howe, and Rob Reich
- Subjects
Sociology and Political Science - Published
- 2003
- Full Text
- View/download PDF
4. The Social Memory of Sexual Violence: "You Touch One, You Touch Us All".
- Author
-
Velte S
- Abstract
The social imaginary that legitimizes sexual violence is continuously reinforced by discourses that are deployed in the aftermath of physical attacks. These, in turn, nourish a specific type of collective memory from which clear social identities emerge. This article identifies the textual trajectories of social meanings associated with sexual violence and their discursive expressions in media, legal, and political discourses. The examples provided here are related to the Spanish "wolf pack case" and its social and political consequences. It concludes that the case not only generated a conceptual battle about violence but also a mnemonic dispute related to newly interpellated subjectivities., Competing Interests: Declaration of Conflicting InterestsThe author declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
5. Characteristics and Practices of High-Performing Centers in Organ Donor Identification and Referral: A Qualitative Study.
- Author
-
Rotteau L, Vaillancourt S, Magaz M, Lo L, Wong BM, Lalani J, Shemie SD, and Zavalkoff S
- Abstract
Background: The identification and referral (ID&R) of potential organ donors to provincial organ donation organizations (ODOs) is a critical first step in the organ donation process. However, even in provinces with mandatory referral legislation, there remains variability in ID&R rates across critical care units, with some units demonstrating high performance despite experiencing similar constraints associated with existing structures, policies, and practices., Objective: We sought to identify the enablers and specific strategies that high-performing critical care units leveraged to achieve their exceptional performance., Design: We conducted a descriptive qualitative study to inform ID&R improvement efforts as part of a positive deviance initiative., Setting: We identified three high-performing critical care units as study sites., Participants: Clinicians working in identified critical care units., Methods: At each site, we interviewed clinical team members about their perceptions and experiences of ID&R. Data analysis followed a thematic analysis approach., Results: We outline three themes describing how the high-performing hospitals achieve strong ID&R practices. First, all units demonstrated a high degree of integration between the concepts of high-quality end-of-life care and organ donation. Team members were consistently notified of successful transplants stemming from their unit, and all missed ID&Rs were tracked and discussed. Second, participants described a team approach with strong medical leadership, where all team members embrace their role in ensuring that no potential donor is missed. Finally, the units adopted strategies to support and simplify ID&R such as collectively simplifying triggers for referral, developing strong working relationships with provincial donor coordinators, and creating informal avenues of communication between clinicians and donor coordinators., Limitations: The lack of comparable data for potential organ donor referral rates across Canada impacted our ability to identify high-performing hospitals based on data. Instead, we contacted the ODOs directly to identify high-performing units that met our criteria. Second, our study sample was limited to three hospital sites from three different provinces and the three hospitals perform organ recovery and transplant on-site., Conclusion: Critical care units can adopt strategies and implement interventions to support ID&R improvement efforts. We provide examples informed by this study. We also highlight considerations that require attention when engaging in this work such as ensuring that all team members are aware of changes in care plans and physicians consistently engage in discussions about organ donation. Local medical leadership is critical to supporting these changes., Competing Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: SZ disclosed funding from the Organ Donation and Transplant Collaborative. SDS disclosed that he is a medical advisor for deceased organ donation at Canadian Blood Services, and he disclosed government work. JL is employed by Canadian Blood Services., (© The Author(s) 2024.)
- Published
- 2024
- Full Text
- View/download PDF
6. Exploring the Health Impact of Intersectional Minority Identity Stressors on Arab Sexual Minority Women Migrants to the United States.
- Author
-
Chaudhry A, Hebert-Beirne J, Alessi EJ, Khuzam MZ, Mitchell U, Molina Y, Wasfie D, Fox S, and Abboud S
- Abstract
Using an intersectionality lens and the minority stress theory as our theoretical grounding, this qualitative study is the first to examine the mental health of Arab sexual minority women (SMW) migrants to the United States. The study aimed to (1) explore the perceptions and experiences of intersectional minority identity-related life stressors and (2) discern their impact on the mental health of first-generation Arab SMW migrants. From December 2022 to March 2023, we conducted 20 semi-structured interviews with Arab SMW migrants. Guided by principles of community engagement in research, four community advisors, including three Arab SMW migrants and a mental health service provider, assisted in mock interviews, recruitment, and data analysis. This enriched our thematic analysis providing a nuanced understanding of Arab SMW migrant experiences. Participants reflected diverse nationalities, socioeconomic statuses, and religions and identified as lesbian, bisexual, or queer. Our sample included asylum seekers, documented migrants, and non-binary individuals (assigned female at birth). Findings revealed three major themes: (1) Community- and Interpersonal-Level Stressors, (2) Strategies for Coping with Stressors, and (3) Impact of Intersectional Life Stressors on Mental Health. Community- and interpersonal-level stressors included challenges navigating migration-related stressors, rejection and discrimination from the Arab, queer, and dominant-group (i.e., non-Arab, non-White) communities, and experiences of invalidation of their intersectional identities. Coping mechanisms included avoidance, identity concealment, and seeking social support. Participants reported various mental health impacts, from anxiety, depression to suicidal thoughts, emphasizing the urgency for tailored interventions. Participants called for the development of support groups specifically for Arab SMW migrants., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
7. Relationship between cyberbullying, anxiety, and depression among university students in Jeddah, Saudi Arabia: A cross-sectional study.
- Author
-
Alghamdi W, Almadani S, Banjer H, Alsulami D, and Alghamdi Y
- Abstract
Objective: Cyberbullying is online aggressive behavior that involves insulting or threatening others, and can cause severe psychological issues, particularly in students. This is often attributed to the frequency and anonymity of the bullying behaviors. Given the lack of research on this issue in Saudi Arabia, the current study sought to evaluate the prevalence of cyberbullying and its relationship with anxiety, depression, and stress among university students in Jeddah., Methods: This cross-sectional study involved administration of an online questionnaire to 877 university students in Jeddah. Cyberbullying and cybervictimization were assessed using the Revised Cyberbullying Inventory scale (RCBI-II) and the Depression, Anxiety, and Stress Scale - 21 Items (DASS-21)., Results: The majority of students had the experience of being a cyberbully (73%), while 54% had been a victim of cyberbullying. No significant association was found between gender and cyberbullying, with both males and females reporting high rates of cyberbullying. The majority of participants (n = 498) also reported significant depressive symptoms. A significant positive association was found between cyberbullying/cybervictimization and depression, anxiety, and stress., Conclusion: A considerable number of university students were found to be victims of cyberbullying, with a strong correlation between cyberbullying and anxiety, depression, and stress, indicating a potential impact on the psychological well-being of students. To address this issue, increased awareness of cyberbullying is needed, along with implementation of preventive measures such as educational campaigns and empathy-building activities among students., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
8. Ankle Muscle Strength and Gait Function After Dorsal Closing Wedge Calcaneal Osteotomy for Haglund Exostosis-Related Heel Pain.
- Author
-
Friesenbichler B, Rutishauer T, Rippstein P, List R, Monn S, Mainzer J, and Maffiuletti NA
- Subjects
- Humans, Male, Female, Adult, Gait Analysis, Young Adult, Prospective Studies, Middle Aged, Exostoses surgery, Exostoses physiopathology, Osteotomy methods, Calcaneus surgery, Calcaneus physiopathology, Muscle Strength physiology, Gait physiology, Heel surgery, Heel physiopathology
- Abstract
Background: Haglund exostosis-related heel pain may be surgically treated with dorsal closing wedge calcaneal osteotomy (DCWCO). Recent reports on this technique show good clinical and self-reported outcomes. However, uncertainty about functional consequences related to ankle muscle strength and gait function due to a shortened Achilles tendon lever arm exists., Methods: Fifteen patients (15 feet) with Haglund exostosis-related heel pain were surgically treated with DCWCO and evaluated before and 1 year after surgery. Isometric plantar flexion and dorsiflexion strength was quantified for both the involved and the uninvolved limb. Gait analysis was performed at a self-selected walking speed using a 3D motion capture system including force plates. Self-reported outcomes (Foot Function Index and Global Treatment Outcome) were also assessed., Results: Before surgery, as well as after surgery, plantar flexion strength of the involved limb was significantly lower compared to the uninvolved limb while dorsiflexion strength did not differ between limbs at both time points. Step length and time, ankle flexion angles, power generation, and propulsive impulses during gait did not differ between limbs both before and after surgery. Propulsive impulse and step length of the involved limb increased from pre- to postsurgery with an effect size of 1.04 and 0.48, respectively, revealing a general improvement in gait dynamics. Total Foot Function Index improved by 48% after surgery, and 80% of patients rated their surgery as "helped" or "helped a lot" (Global Treatment Outcome)., Conclusion: In this relatively small cohort, we found that patients treated for Haglund exostosis-related heel pain with DCWCO surgery had minor interlimb differences in gait kinematics and kinetics and generally improved gait dynamics and self-reported function at 1-year follow-up., Level of Evidence: Level II, observational prospective cohort study., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Disclosure forms for all authors are available online.
- Published
- 2024
- Full Text
- View/download PDF
9. The Association Between Maternal Depressive Symptoms and Toddlers' Developmental and Behavioral Problems: A Population-Based Study.
- Author
-
Wu PC, de Banate MA, Kim H, Viner-Brown S, and High P
- Subjects
- Female, Child, Child, Preschool, Humans, Pregnancy, Emotions, Mothers psychology, Postpartum Period psychology, Depression diagnosis, Depression, Postpartum epidemiology, Depression, Postpartum psychology
- Abstract
This study aims to compare the developmental-behavioral profiles of 2-year-olds of mothers who experienced postpartum and/or current depression with profiles of toddlers of mothers without depression at either time using population-based Rhode Island data. Weighted data from Rhode Island Department of Health's Pregnancy Risk Assessment Monitoring System and Rhode Island's follow-up Toddlers Wellness Overview Survey distributed to mothers giving birth between 2006 and 2008 were analyzed. Compared with non-depressed mothers, those with any depression following childbirth reported more concerns with their toddlers' receptive language, social-emotional development, and their sleep and feeding behaviors. When adjusted for demographics, persistent depression remained associated with social-emotional (adjusted odds ratio [aOR] = 7.53, 2.78-20.34) and feeding concerns (aOR = 3.13, 1.36-7.22), and current depression was associated with social-emotional concerns (aOR = 2.52, 1.26-5.01). We conclude that pediatric providers should explore maternal mental health as a mediating and potentially modifiable factor beyond the postpartum period when toddlers present with developmental-behavioral challenges., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
10. Trauma-Informed Care Training in U.S. and Canadian Ob/Gyn Residencies.
- Author
-
DeAndrade S, Pelletier A, Grossman S, Lewis-O'Connor A, Dutton C, Royce CS, and Bartz D
- Abstract
This is a cross-sectional study investigating the prevalence and nature of trauma-informed care (TIC) training in obstetrics and gynecology residency programs. In our sample, 20% of programs had annual TIC training, 53% had less than annual training, and 27% had no training at all. Only 25.3% of respondents were satisfied with their current training in interpersonal trauma and TIC. A lack of facilitators to conduct such training was the primary barrier to implementing TIC. Significant opportunity exists to improve TIC education for Ob/Gyn trainees., Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
11. Impact of an Enhanced Recovery after Surgery Protocol on Postoperative Outcomes in Cardiac Surgery.
- Author
-
Bills S, Wills B, Boyd S, and Elbeery J
- Subjects
- Adult, Humans, Analgesics, Opioid, Constipation, Length of Stay, Pain, Pain, Postoperative epidemiology, Cardiac Surgical Procedures adverse effects, Enhanced Recovery After Surgery, Respiratory Insufficiency complications
- Abstract
Background: Enhanced recovery after surgery (ERAS) protocols are perioperative care pathways designed to achieve early recovery after procedures. ERAS protocols have shown shortened recovery time, and lower opioid utilization and postoperative complication rates. Evidence to support the use of ERAS protocols is robust, however, minimal data exists in cardiac surgery patients. Methods: This observational cohort compared adults receiving post-operative care after coronary artery bypass or valve procedures who received an ERAS protocol containing acetaminophen, gabapentin, and methocarbamol to historical controls. The primary outcome of this study was postoperative opioid use during the first 72-hours following cardiac surgery. Secondary outcomes included length of stay, average pain scores 72-hours postoperatively, and incidence of opioid-related complications. Results: Total cumulative 72-hour post-operative opioid consumption showed a trend toward reduction in opioid use in patients who received the ERAS protocol vs the historic control group [75.8 mg vs 105.4 mg oral morphine equivalents (P = .09)]. Median postoperative lengths of stay and pain scores were similar between groups. Opioid related complications including constipation and respiratory depression occurred more frequently in the control group compared to the ERAS group [47.7% vs 60.5% ( P < .05) and 57.1% vs 62.7% ( P < .05) respectively]. Conclusions: Use of an ERAS protocol shows a promising trend toward less postoperative opioid use in cardiac surgery patients. Lower rates of opioid-related adverse events, including constipation and respiratory depression, were observed in the ERAS protocol group. This study indicates that ERAS protocols have a potential role for cardiac surgery patients postoperatively., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. FundingThe author(s) received no financial support for the research, authorship, and/or publication of this article.
- Published
- 2023
- Full Text
- View/download PDF
12. Family Carers of People with Dementia in Japan, Spain, and the UK: A Cross-Cultural Comparison of the Relationships between Experiential Avoidance, Cognitive Fusion, and Carer Depression.
- Author
-
Kishita N, Morimoto H, Márquez-González M, Barrera-Caballero S, Vara-García C, Van Hout E, Contreras M, and Losada-Baltar A
- Subjects
- Humans, Spain, Depression, Cross-Cultural Comparison, Japan, United Kingdom, Cognition, Caregivers psychology, Dementia psychology
- Abstract
Objective and research design This study investigated whether the relationship between experiential avoidance and carer depression is mediated by cognitive fusion using path analysis and whether this model differs between family carers from Japan, Spain, and the UK using multi-group path analysis. Results The whole sample model ( N = 745) showed a good fit to the data. The direct effect of experiential avoidance on carer depression ( β = .10) and its indirect effect on carer depression through cognitive fusion ( β = .15) were significant. Examined variables accounted for 45% of the variance of depression. Multi-group path analysis confirmed the same pattern of indirect path across 3 countries, while the direct path was no longer significant in Spanish and UK samples. Conclusion These findings suggest that targeting cognitive fusion may be particularly critical in culturally diverse carers and pre-emptive efforts to reduce experiential avoidance using psychological techniques may be beneficial among family carers prone to cognitive fusion regardless of cultural differences.
- Published
- 2023
- Full Text
- View/download PDF
13. The Likelihood of Early Guilty Pleas Following Digitally Recorded Victim Statements for Family Violence.
- Author
-
Walton D, Ellwood R, and Martin S
- Subjects
- Guilt, Humans, Criminal Law, Domestic Violence
- Abstract
This study follows 4715 Family Harm cases for which charges are laid (from around 15,000 events from 2018-2020). Comparisons are made between cases where a digitally recorded victim video statement (VVS) is taken to those who (1) make a written statement, (2) refuse to make any statement and (3) present at the public counter and make a written statement. Findings indicate that VVS increases the rates of an early guilty plea by 95% (OR = 1.95, LCL = 1.34, UCL = 2.7) compared to those who decline a VVS and have a written statement. No difference is observed for those presenting to report an event at a public counter. A more modest effect is observed comparing those who refuse a statement altogether (OR = 1.28, LCL = 1.03, UCL = 1.60). A VVS is nearly twice as likely to lead to an early guilty plea. It is reasoned that there is a poor rate of guilty pleas for written statements, rather than an elevation in rates for VVS. Age and gender are unrelated to the elevated rate of pleading guilty to a VVS. Event seriousness is inversely related to pleading guilty, whereas having many prior convictions or being remanded increases the likelihood of the guilty plea.
- Published
- 2022
- Full Text
- View/download PDF
14. Psychological Autopsy: A Method to Assist in the Identification of Risk and Protective Factors for Intimate Partner Femicide.
- Author
-
McPhedran S, Eriksson L, Arnautovska U, Mazerolle P, and Johnson H
- Subjects
- Autopsy, Female, Health Services, Homicide psychology, Humans, Protective Factors, Intimate Partner Violence psychology, Sexual Partners psychology
- Abstract
The most common form of violence experienced by women is that perpetrated by intimate partners, and the gendered nature of intimate partner femicide (IPF) has received particular attention. Few studies to date have delved into the limitations associated with methods used in IPF research, and particularly the methods used to study homicide victims (rather than homicide perpetrators). This article outlines dominant methodologies used to study IPF, and considers a novel method of investigation-the "psychological autopsy"-that may help to improve existing knowledge about IPF.
- Published
- 2022
- Full Text
- View/download PDF
15. Using Emergency Medical Services Data to Monitor Nonfatal Opioid Overdoses in Real Time : Development, Validation, and Use of a Case Definition, Rhode Island, 2018.
- Author
-
Hallowell BD, Chambers LC, Rhodes J, Basta M, Viner-Brown S, and Lasher L
- Subjects
- Adult, Civil Defense statistics & numerical data, Emergency Medical Services methods, Humans, Naloxone therapeutic use, Narcotic Antagonists therapeutic use, Opiate Overdose epidemiology, Rhode Island, Civil Defense standards, Emergency Medical Services statistics & numerical data, Opiate Overdose diagnosis, Time Factors
- Abstract
Objective: No case definition exists that allows public health authorities to accurately identify opioid overdoses using emergency medical services (EMS) data. We developed and evaluated a case definition for suspected nonfatal opioid overdoses in EMS data., Methods: To identify suspected opioid overdose-related EMS runs, in 2019 the Rhode Island Department of Health (RIDOH) developed a case definition using the primary impression, secondary impression, selection of naloxone in the dropdown field for medication given, indication of medication response in a dropdown field, and keyword search of the report narrative. We developed the case definition with input from EMS personnel and validated it using an iterative process of random medical record review. We used naloxone administration in consideration with other factors to avoid misclassification of opioid overdoses., Results: In 2018, naloxone was administered during 2513 EMS runs in Rhode Island, of which 1501 met our case definition of a nonfatal opioid overdose. Based on a review of 400 randomly selected EMS runs in which naloxone was administered, the RIDOH case definition accurately identified 90.0% of opioid overdoses and accurately excluded 83.3% of non-opioid overdose-related EMS runs. Use of the case definition enabled analyses that identified key patterns in overdose locations, people who experienced repeat overdoses, and the creation of hotspot maps to inform outbreak detection and response., Practice Implications: EMS data can be an effective tool for monitoring overdoses in real time and informing public health practice. To accurately identify opioid overdose-related EMS runs, the use of a comprehensive case definition is essential.
- Published
- 2021
- Full Text
- View/download PDF
16. Using Timely Overdose Data to Address a Spike in Nonfatal Overdoses and Inform a Coordinated Community-Level Response in Rhode Island, 2019.
- Author
-
Lasher L, Hallowell BD, Chambers LC, Koziol J, McDonald J, Elmaleh R, Karim S, and Viner-Brown S
- Subjects
- Adult, Drug Overdose epidemiology, Emergency Service, Hospital organization & administration, Emergency Service, Hospital statistics & numerical data, Female, Humans, Male, Middle Aged, Rhode Island epidemiology, Community Support, Drug Overdose prevention & control, Time Factors
- Abstract
The Rhode Island Department of Health (RIDOH) uses emergency department data to monitor nonfatal opioid overdoses in Rhode Island. In April 2019, RIDOH detected an increase in nonfatal opioid overdoses in Woonsocket, Rhode Island, and sent an alert to state and local partners (eg, fire departments, emergency departments, faith leaders) with guidance on how to respond. To guide community-level, strategic response efforts, RIDOH analyzed surveillance data to identify overdose patterns, populations, and geographic areas most affected. During April-June 2019, nonfatal opioid overdoses in Woonsocket increased 463% (from 13 to 73) when compared with the previous 3 months. Because of the sustained increase in nonfatal opioid overdoses, RIDOH brought together community partners at a meeting in June 2019 to discuss RIDOH opioid overdose data and coordinate next steps. Data analyses were essential to framing the discussion and allowed community partners at the event to identify an unexpected increase in cocaine-involved nonfatal opioid overdoses in Woonsocket. Many patients with cocaine-involved nonfatal overdoses also had fentanyl in their system, and input from community partners suggested that many patients were unaware of using fentanyl. Community response actions included targeting harm reduction services (eg, distribution of naloxone, mobile needle exchange); deploying peer recovery support specialists to overdose hotspots to connect people to treatment and recovery resources; placing harm reduction messaging in high-traffic areas; and targeted social media messaging. After the meeting, nonfatal opioid overdoses returned to pre-outbreak levels. This case study provides an example of how timely opioid overdose data can be effectively used to detect a spike in nonfatal opioid overdoses and inform a strategic, community-level response.
- Published
- 2021
- Full Text
- View/download PDF
17. Ex Vivo Human Skin: An Alternative Test System for Skin Irritation and Corrosion Assays.
- Author
-
Eberlin S, Facchini G, da Silva GH, Eberlin S, Bragatto AR, Pinheiro ALTA, and da Silva Pinheiro A
- Subjects
- Animal Testing Alternatives, Animals, Corrosion, Humans, Skin, Irritants toxicity, Skin Irritancy Tests
- Abstract
Native human skin has been reported in the literature as being an important experimental model for studying skin biology. Studies performed by our group have shown that ex vivo skin, from elective plastic surgery, maintains the biological characteristics of native skin under specific culture conditions. As such, it might be a feasible model for the safety and efficacy testing of topical substances. While Brazil is at the forefront of global regulation implementation, Brazilian researchers are not always able to transfer certain widely used protocols to their laboratories, particularly protocols that involve the use of reconstructed tissues with limited viability, such as those for skin corrosion (OECD TG 431) and irritation testing (OECD TG 439). In this study, we investigated the applicability of the ex vivo skin model to the evaluation of irritation and corrosion potential of a number of proficiency substances described in TG 431 and TG 439. The skin fragments were standardised in size and diameter, and placed into cell culture inserts. The experimental protocol was conducted according to TG 431 and TG 439. The results obtained show that ex vivo skin could represent a promising tool for the evaluation of irritation and corrosion potential of substances (subject to inclusion and exclusion criteria), as recommended by OECD guidelines. While this is a proof-of-concept study, the use of ex vivo skin should be considered for such testing.
- Published
- 2021
- Full Text
- View/download PDF
18. Mind Over Matter: Confronting Challenges in Post-Mortem Brain Biobanking for Glioblastoma Multiforme.
- Author
-
Griffin C, Vilain R, King S, Nixon S, Gooley A, Bray S, Lynam J, Walker MM, Scott RJ, and Paul C
- Abstract
Over the past 10 years, there has been limited progress for the treatment of brain cancer and outcomes for patients are not much improved. For brain cancer researchers, a major obstacle to biomarker driven research is limited access to brain cancer tissue for research purposes. The Mark Hughes Foundation Brain Biobank is one of the first post-mortem adult brain banks in Australia to operate with protocols specifically developed for brain cancer. Located within the Hunter New England Local Health District and operated by Hunter Cancer Biobank, the boundaries of service provided by the Brain Bank extend well into the surrounding regional and rural areas of the Local Health District and beyond. Brain cancer biobanking is challenging. There are conflicting international guidelines for best practice and unanswered questions relating to scientific, psychosocial and operational practices. To address this challenge, a best practice model was developed, informed by a consensus of existing data but with consideration of the difficulties associated with operating in regional or resource poor settings. The regional application of this model was challenged following the presentation of a donor located in a remote area, 380km away from the biobank. This required biobank staff to overcome numerous obstacles including long distance patient transport, lack of palliative care staff, death in the home and limited rural outreach services. Through the establishment of shared goals, contingency planning and the development of an informal infrastructure, the donation was facilitated within the required timeframe. This experience demonstrates the importance of collaboration and networking to overcome resource insufficiency and geographical challenges in rural cancer research programmes., Competing Interests: Declaration Of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2021.)
- Published
- 2021
- Full Text
- View/download PDF
19. Criminal Careers Among Female Perpetrators of Family and Nonfamily Homicide in Australia.
- Author
-
Eriksson L, McPhedran S, Caman S, Mazerolle P, Wortley R, and Johnson H
- Subjects
- Australia epidemiology, Child, Female, Homicide, Humans, Prevalence, Criminals, Women
- Abstract
Knowledge of women's pathways to serious offending, including homicide, is limited. This study contributes to a small but growing body of literature examining the criminal careers of serious female offenders by using interview data with females convicted of murder or manslaughter in Australia to examine various dimensions of their criminal careers, specifically, prevalence, frequency, age of onset, duration, and offending variety. In particular, in this study we compared criminal career dimensions across women who had killed a family member (e.g., intimate partner, children) and those whose victims were not part of the family unit (i.e., acquaintances or strangers). Our findings reveal differences between female homicide offenders who kill within and outside of the family unit. Although both groups had comparable overall lifetime prevalence of self-reported participation in criminal offending, findings indicate that participation among the family group was typically at low levels of frequency, of limited duration, and with relatively little variety in categories of offending. The family group also reported lower contact with the criminal justice system compared with the nonfamily group, and were less likely to have experienced some form of criminal/legal sanction in the 12 months prior to the homicide incident. This suggests that women who kill family members are more "conventional" than their nonfamily counterparts, in terms of having low and time-limited (i.e., short duration) lifetime participation in criminal offending.
- Published
- 2021
- Full Text
- View/download PDF
20. Australian Mass Shootings: An Analysis of Incidents and Offenders.
- Author
-
McPhedran S
- Subjects
- Australia epidemiology, Homicide, Humans, United States epidemiology, Criminals, Firearms, Mass Casualty Incidents, Wounds, Gunshot epidemiology
- Abstract
Mass shooting events are relatively underresearched, and most study comes from the United States. Despite significant international interest, little is known about other countries' experiences of these events. The current study examines Australian mass shooting incidents and offenders, with emphasis on mental illness, life strains, and offenders' life histories. Australia had 14 mass shootings between 1964 and 2014. Most offenders experienced acute life stressors and/or chronic strains leading up to the event; however, diagnosed mental illness was less commonly documented. These observations provide new information about mass shooting incidents and offenders, and can help to inform international policy development.
- Published
- 2020
- Full Text
- View/download PDF
21. The Ex Vivo Skin Model as an Alternative Tool for the Efficacy and Safety Evaluation of Topical Products.
- Author
-
Eberlin S, Silva MSD, Facchini G, Silva GHD, Pinheiro ALTA, Eberlin S, and Pinheiro ADS
- Subjects
- Animals, Cells, Cultured, Humans, Surgery, Plastic, Animal Testing Alternatives methods, Animal Testing Alternatives standards, Cell Culture Techniques standards, Skin cytology
- Abstract
The development of alternative approaches for safety and efficacy testing that avoid the use of animals is a worldwide trend, which relies on the improvement of current models and tools so that they better reproduce human biology. Human skin from elective plastic surgery is a promising experimental model to test the effects of topically applied products. As the structure of native skin is maintained, including cell population (keratinocytes, melanocytes, Langerhans cells and fibroblasts) and dermal matrix (containing collagen, elastin, glycosaminoglycans, etc.), it most closely matches the effects of substances on in vivo human skin. In this review, we present a collection of results that our group has generated over the last years, involving the use of human skin and scalp explants, demonstrating the feasibility of this model. The development of a test system with ex vivo skin explants, of standard size and thickness, and cultured at the air-liquid interface, can provide an important tool for understanding the mechanisms involved in several cutaneous disorders.
- Published
- 2020
- Full Text
- View/download PDF
22. Mixed Adenocarcinomatous and Neuroendocrine Tumor of the Urinary Bladder With Concomitant Carcinoma In Situ: A Case Report With a Comprehensive Immunohistochemical Analysis and Review of the Literature.
- Author
-
Tränkenschuh W, Biesdorf AS, Papadimas N, Samara S, Hefty R, and Stahl PR
- Subjects
- Adenocarcinoma pathology, Adenocarcinoma surgery, Aged, Biomarkers, Tumor analysis, Carcinoma in Situ pathology, Carcinoma in Situ surgery, Carcinoma, Neuroendocrine pathology, Carcinoma, Neuroendocrine surgery, Cystectomy, Humans, Immunohistochemistry, Male, Neoplasm Invasiveness pathology, Neoplasms, Complex and Mixed pathology, Neoplasms, Complex and Mixed surgery, Urinary Bladder pathology, Urinary Bladder surgery, Urinary Bladder Neoplasms pathology, Urinary Bladder Neoplasms surgery, Urothelium pathology, Urothelium surgery, Adenocarcinoma diagnosis, Carcinoma in Situ diagnosis, Carcinoma, Neuroendocrine diagnosis, Neoplasms, Complex and Mixed diagnosis, Urinary Bladder Neoplasms diagnosis
- Abstract
Mixed adenoneuroendocrine carcinomas are rare and usually occur in the gastrointestinal tract. Although there have been several investigations regarding their developmental mechanism, the molecular origin of these tumors remains unclear. In this article, we present an exceedingly rare case of a mixed tumor of the urinary bladder with an adenocarcinomatous and a neuroendocrine component and a concomitant urothelial carcinoma in situ (CIS). Due to this extraordinary combination of tumor components, our goal was to extensively examine the 3 tumor components with regard to a representable common origin. Therefore, a comprehensive immunohistochemical analysis and review of the literature was performed. Besides expected outcome, our examination also revealed surprising staining results. Urothelial CIS, like the adenocarcinomatous component, showed strong staining for CDX2. In addition, parts of the adenocarcinoma were positive for synaptophysin like the neuroendocrine tumor component. All 3 components showed a significant overexpression of p53 and a moderate to strong membranous and cytoplasmatic staining for β-catenin. To our knowledge, we are the first to describe a case of a mixed tumor of the urinary bladder with an adenocarcinomatous and a neuroendocrine component and a concomitant CIS. The components share striking molecular features that argue for a common clonal origin and a development of the invasive tumor via the urothelial precursor lesion.
- Published
- 2019
- Full Text
- View/download PDF
23. Characteristics of Homicide-Suicide in Australia: A Comparison With Homicide-Only and Suicide-Only Cases.
- Author
-
McPhedran S, Eriksson L, Mazerolle P, De Leo D, Johnson H, and Wortley R
- Subjects
- Adult, Australia, Crime Victims psychology, Criminal Psychology, Female, Homicide trends, Humans, Male, Social Environment, Suicide trends, Crime Victims statistics & numerical data, Homicide psychology, Social Values, Suicide psychology
- Abstract
Homicide-suicide represents one of the rarest forms of lethal violence but often precipitates calls to revise social, health, and justice policies. However, there is little empirical information about this type of violence. The current study uses two unique data sets to examine a wide range of individual and situational characteristics of homicide-suicide, with particular emphasis on establishing whether and how homicide-suicide differs from homicide-only and suicide-only. Findings suggest homicide-suicide may have unique characteristics that set it apart from both homicide-only and suicide-only, as well as sharing certain other characteristics with those two types of events.
- Published
- 2018
- Full Text
- View/download PDF
24. An Evaluation of the Impacts of Changing Firearms Legislation on Australian Female Firearm Homicide Victimization Rates.
- Author
-
McPhedran S
- Subjects
- Adult, Australia, Bayes Theorem, Female, Firearms statistics & numerical data, Humans, Male, Sex Factors, United States, Firearms legislation & jurisprudence, Homicide statistics & numerical data, Intimate Partner Violence statistics & numerical data
- Abstract
Reducing lethal violence against women requires comprehensive measures addressing individual, social, economic, cultural, and situational factors. Regarding situational factors, access to weapons-and firearm access in particular-has received notable research attention. However, most study comes from the United States of America, and findings may not apply elsewhere. The current study examines whether changing gun laws in Australia affected female firearm homicide victimization. Female firearm homicide victimization may have been affected; however, no significant impacts were found for male firearm homicide victimization. Findings suggest there may be value in preventing legal access to firearms by persons who have a history of intimate partner violence, although considerable further study is required.
- Published
- 2018
- Full Text
- View/download PDF
25. Occupational Safety and Health in the Temporary Services Industry: A Model for a Community-University Partnership.
- Author
-
Bonney T, Forst L, Rivers S, Love M, Pratap P, Bell T, and Fulkerson S
- Subjects
- Humans, Occupational Health Services standards, Workplace, Health Promotion, Industry, Occupational Health, Occupational Health Services organization & administration, Universities
- Abstract
Workers in the temporary staffing industry face hazardous working conditions and have a high risk of occupational injury. This project brought together local workers' centers and university investigators to build a corps of Occupational Health Promoters (OHPs) and to test a survey tool and recruitment methods to identify hazards and raise awareness among workers employed by temporary staffing companies. OHPs interviewed ninety-eight workers employed by thirty-three temporary agencies and forty-nine client companies, working mainly in shipping and packing, manufacturing, and warehousing sectors. Surveys identified workplace hazards. OHPs reported two companies to OSHA, resulting in several citations. Partners reported greater understanding of occupational safety and health challenges for temporary workers and continue to engage in training, peer education, and coalition building.
- Published
- 2017
- Full Text
- View/download PDF
26. Lethal and non-lethal violence against women in Australia: measurement challenges, conceptual frameworks, and limitations in knowledge.
- Author
-
McPhedran S and Baker J
- Subjects
- Australia, Data Collection, Female, Homicide trends, Humans, Male, Quality Improvement, Research Design standards, Risk, Spouse Abuse mortality, Aggression classification, Criminals classification, Homicide statistics & numerical data, Sexual Partners, Spouse Abuse statistics & numerical data
- Abstract
Understanding pathways from non-lethal violence to lethal violence between intimate partners is a notable challenge for both policy and practice in partner violence prevention. Of particular interest is whether lethal violence represents an "escalation" of violence from "low" to "high" risk over time, or is best predicted by specific behavioral "typologies" of perpetrators. Testing the "escalation" and "typology" theories is hampered in Australia by limitations in knowledge about non-lethal and lethal violence against women. This article discusses data limitations, measurement problems, and conceptual shortcomings, and suggests approaches to improving evidence quality in the field of violence prevention and risk assessment.
- Published
- 2012
- Full Text
- View/download PDF
27. The labor of a lifetime?: health and occupation type as predictors of workforce exit among older Australians.
- Author
-
McPhedran S
- Subjects
- Australia, Female, Humans, Longitudinal Studies, Male, Middle Aged, Employment statistics & numerical data, Health Status, Occupations classification, Retirement statistics & numerical data
- Abstract
Objective: The structural aging of the population and withdrawal of older people from the labor force have become common themes within Western social policy discourse and have particular relevance to policy development around health and aging. The current study examines whether particular occupation types are associated with both poor health and an increased likelihood of labor force exit., Methods: Longitudinal data are used to examine workforce participation among older Australians (aged between 55 and 64, in 2002)., Results: Older workers in trades, labor, and production occupations, the majority of whom are men, have poorer general health than their counterparts in other occupations and are also the most likely to exit the workforce., Discussion: These findings suggest that a number of older men in Australia (and, indeed, elsewhere) may face both poor health and limited employment opportunities in areas that match their abilities and experience. These individuals may experience a number of years out of the labor force, highlighting a role for targeted policies and programs.
- Published
- 2012
- Full Text
- View/download PDF
28. Firearm homicide in Australia, Canada, and New Zealand: what can we learn from long-term international comparisons?
- Author
-
McPhedran S, Baker J, and Singh P
- Subjects
- Australia, Canada, Humans, New Zealand, Time, Firearms statistics & numerical data, Homicide statistics & numerical data, Internationality
- Abstract
Although firearm homicide remains a topic of interest within criminological and policy discourse, existing research does not generally undertake longitudinal comparisons between countries. However, cross-country comparisons provide insight into whether "local" trends (e.g., declines in firearm homicide in one particular country) differ from broader, international trends. This in turn can improve knowledge about the role of factors such as policing practices and socioeconomic variables in the incidence of lethal violence using firearms. The current study compares long-term firearm homicide trends in three countries with similar social histories but different legislative regimes: Australia, Canada, and New Zealand. Using negative binomial regression, the study found that the most pronounced decline in firearm homicide over the past two decades occurred in New Zealand. Connections between social disadvantage, policing policy, and violence are discussed.
- Published
- 2011
- Full Text
- View/download PDF
29. Spontaneous thrombosis of congenital extrahepatic portosystemic shunt (Abernethy malformation) simulating inguinal hernia incarceration.
- Author
-
Afzal S, Nair A, Grainger J, Latif S, and Rehman AU
- Subjects
- Adult, Anticoagulants therapeutic use, Azygos Vein abnormalities, Diagnosis, Differential, Humans, Magnetic Resonance Angiography, Male, Phlebography, Portal Vein diagnostic imaging, Tomography, X-Ray Computed, Treatment Outcome, Vascular Malformations complications, Vascular Malformations diagnostic imaging, Vena Cava, Inferior diagnostic imaging, Venous Thrombosis diagnostic imaging, Venous Thrombosis drug therapy, Warfarin therapeutic use, Hernia, Inguinal diagnosis, Portal Vein abnormalities, Vascular Malformations diagnosis, Vena Cava, Inferior abnormalities, Venous Thrombosis etiology
- Abstract
Tender lumps in the inguinal region are often explored emergently to treat suspected hernial strangulation. We discuss the case of an adult male who presented acutely with a tender inguinal swelling and raised inflammatory markers and was therefore deemed as requiring surgical exploration. However preoperative abdominal computerized tomography (CT) revealed an extensive thrombosing congenital venous malformation of portosystemic origin with extension into the symptomatic inguinal canal. A potentially lethal exsanguination from surgery was thus avoided.
- Published
- 2010
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.