1. Effect of SRD-P401 on the Discomfort of Neck and/or Shoulder Stiffness
- Author
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Katsumi Kido, Ruka Goto, Akira Iizuka, Yasuhiro Komatsu, Chiaki Kudoh, Maasa Sonoda, and Tokunori Matsui
- Subjects
Analgesic effect ,Aspirin ,biology ,business.industry ,Stomach ,General Medicine ,Shoulder stiffness ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Healthy food ,030220 oncology & carcinogenesis ,Anesthesia ,medicine ,biology.protein ,Potency ,Cyclooxygenase ,business ,Adverse effect ,030217 neurology & neurosurgery ,medicine.drug - Abstract
SRD-P401 is a newly developed healthy food supplement which has an anti-inflammatory and analgesic effect. In this report, the effects of SRD-P401 on neck and shoulder stiffness were assessed by an inquiry method in the public field. The stiffness symptoms of all participants were improved after taking SRD-P401. The symptoms of the participants who took 3 g/day and/or 9 g/day of SRD-P401 improved in a week after taking it. Unpleasant adverse effects in stomach and alimentally organs were not found during the test period. SRD-P401 showed the anti-nociceptive effect on the acetic-acid-induces abdominal writhing in rats. The potency was equivalent to aspirin. Moreover, to investigate the ability of the anti-inflammatory effects of SRD-P401, we exerted by inhibiting the Cyclooxygenase (COX) enzyme activity. SRD-P401 and its constituents inhibit the COX activity. The results of this field test indicated SRD-P401 would be a beneficial and useful healthy food supplement for a person with stiffness in neck and/or shoulder.
- Published
- 2017
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