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Background and Objective: A consensus exercise was carried out to address unmet needs in the classification, diagnosis, and management of patients with chronic noninfectious uveitis affecting the posterior segment (NIU-PS), with a focus on chronic postoperative inflammation/cystoid macular edema. Methods: Eight experts participated in roundtable discussions and consensus-building exercises to develop clear guidelines for the diagnosis and management of chronic NIU-PS. The group addressed questions surrounding clinical features, diagnostic tests, and treatment considerations. Results: Clinicians agreed that chronic uveitis/intraocular inflammation should be defined as having persistence or recurrence for 3 or more months. Diagnosis is informed by evaluation of signs and symptoms, use of imaging, and exclusion of infectious etiologies. Management should be initiated with the least invasive therapies, proceeding to intraocular injections, and/or long-term intravitreal or systemic therapies, as necessary. Conclusion: This article offers an up-to-date consensus guideline based on clinical experience. Future clinical trials may help to test and reevaluate these recommendations. [Ophthalmic Surg Lasers Imaging Retina 2024;55:652–658.] [ABSTRACT FROM AUTHOR]

Background and Objective: Outer retinal tubulation (ORT) is observed on optical coherence tomography images from patients with geographic atrophy (GA), but its clinical implications are unclear. The objective of this study was to investigate the prevalence of ORT and its association with GA lesion growth rates. Materials and Methods: This post hoc longitudinal analysis assessed 62 eyes randomized to sham treatment in the phase 2 FILLY trial. ORT prevalence was estimated at baseline, month 12, and month 18 and change in GA lesion growth from baseline to month 18 was calculated. Results: ORT prevalence rates were 24%, 43%, and 43% at baseline, month 12, and month 18, respectively. Slower mean GA lesion growth was observed in eyes with ORT present at baseline in the overall population as well as the subfoveal and nonsubfoveal GA subgroups. Conclusion: ORT presence may indicate a slower-growing GA lesion phenotype, independent of foveal involvement. [Ophthalmic Surg Lasers Imaging Retina 2024;55:448–451.] [ABSTRACT FROM AUTHOR]

The article offers information on acute bilateral angle closure that emerges when a myopic shift occurs when the lens becomes dislocated anteriorly or when the ciliary body becomes rotated anteriorly; and also discusses cases wherein the uveal effusion is secondary to underlying inflammatory conditions.

The article presents the case study of a 21-year-old African American woman with gradual decline in vision in both eyes. The patient's visual acuity and medical history is discussed whose pupils were reactive to light and symmetrically round and had systemic lupus erythmatosus (SLE). The patient was diagnosed with SLE retinopathy that led to severe vision loss.

The article presents a case study on clinical findings involving pregnant woman with floaters and decreased vision. Topics include differential diagnosis for unilateral panuveitis, infectious, inflammatory and neoplastic syndromes, and endogenous endophthalmitis which is considered in the differential diagnosis of new onset vision loss with associated intraocular inflammation.

The article describes the case of a young child referred for difficulty seeing in the dark and challenges the reader to make a diagnosis based on clinical findings.

The article presents a primer on unilateral vision loss. Topics covered include differential diagnosis, diagnosis and management, the vascular causes of unilateral vision loss which include central retinal vein occlusion (CRVO), central retinal artery occlusion (CRAO), and diabetic retinopathy and ocular ischemic syndrome (OIS).

The article presents a case study of a 19-year-old female college student was referred for retinal evaluation of her left eye. The topics discussed include results of the fundus examination of the patients left eye, features of Optic nerve pits, association of congenital optic nerve pits with maculopathy, and treatment for optic pit maculopathy.

The article presents a case of a female patient who visited an eye clinic because of progressive decrease in vision in her right eye. It discusses the differential diagnosis of optic neuritis with multiple posterior fundus lesions without exposure to infectious entities except for tuberculosis and herpes simplex. It describes the treatment of the disease using high dose of oral prednisone with improvement in her ocular pain and headache. A brief description of the disease is provided.

Both eyes showed flamed-shaped hemorrhages and macular exudates on fundus examination. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 36-year old Brazilian man who was taken to the New England Eye Center due to constant headache and worsening vision. The patient has an unremarkable medical and ocular histories and does not undergo medication. Dilated fundus examination of his right and left eye revealed hemorrhages, nerve fiber layer infarcts, optic disc margin obscuration and macular exudates. Also discussed in this article are malignant hypertension and high blood pressure.

The article presents a case study of an adolescent with valsalva retinopathy.