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Objective: To describe the frequency and factors related to mortality in children with Rocky Mountain fever spotted (RMSF) treated for 14 years at the Hospital Infantil del estado de Sonora. Material and methods: This is a retrospective cohort of 203 children, treated between 2003 and 2016. Clinical and laboratory data were compared between patients who died and those who survived. Chi-square and Student's t were used for comparison between groups; a p value <0.05 was considered statistically significant. Results: The overall mortality was 26.6%, in the period 2003-2008 happened the highest number of deaths, up to 66% in one year. In recent years, mortality has decreased to 14.3%. Statistically significant clinical features of poor prognosis were: edema of wrists, vasculitis, abdominal pain, renal failure and elevation of transaminases (SGOT and TGP). In recent years, the time of antibiotic initiation has decreased, but it has not been achieved on average ≤ 5 days. Conclusions: In children with RMSF, in this 14-year experience, an important decrease in mortality has been observed; however, more efforts should be made to achieve mortality between 3 and 7%, as has already been reported. [ABSTRACT FROM AUTHOR]

Objective: To describe the clinical and laboratory characteristics of the exanthematous disease by chikungunya virus (CHIKV). Material and methods: Review of clinical fi les with diagnosis of CHIKV occurred in the Children's Hospital of the State of Sonora, during the year 2015. Results: Five cases were resolved without complications in the acute phase and one case developed arthritis and arthralgia with three months of evolution without presenting orthopedic sequelae. One case with mild thrombocytopenia, four children developed lymphopenia and one case with neutropenia, leukopenia and lymphopenia. Conclusions: All six cases presented a favorable evolution; no child had the characteristic feature of buckling disease due to pain or any sequelae. [ABSTRACT FROM AUTHOR]

Two clinical cases of Rocky Mountain spotted fever in children with different clinical course are presented. One patient had a satisfactory evolution, since the specific treatment was initiated within the first five days of initiating the symptoms; while the other patient had a fatal outcome, with necrosis and gangrene in lower extremities. In both cases, diagnosis was confirmed by skin biopsy using the technique of Pinkerton. [ABSTRACT FROM AUTHOR]