Search

Using the European Union's Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) ecotoxicity data, this paper compares 3 different approaches to calculate final substance toxicity hazard values using the USEtox approach (chronic EC50 + acute EC50/2), using only acute EC50 equivalent data (EC50 eq ), and using only chronic no observed effect concentration equivalent (NOEC eq) data. About 4008, 4853, and 5560 substance hazard values could be calculated for the USEtox model, acute only, and chronic only approaches, respectively. The USEtox model provides hazard values similar to the ones based on acute EC50 data only. Although there is a large amount of variability in the ratios, the data support acute EC50 eq to chronic NOEC eq ratios (calculated as geometric mean) of 10.64, 10.90, and 4.21 for fish, crustaceans, and algae respectively. Comparison of the calculated hazard values with the criteria used by the EU chemical Classification, Labelling, and Packaging regulation (CLP) shows the USEtox model underestimates the number of compounds categorized as very toxic to aquatic life and/or having long-lasting effects. In contrast, use of the chronic NOEC data shows a good agreement with CLP. It is therefore proposed that chronic NOEC eq are used to derive substance hazard values to be used in the EU Environmental Footprint. Due to poor data availability for some chemicals, the uncertainty of the final hazard values is expected to be high. Integr Environ Assess Manag 2019;15:796-807. © 2019 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC)., (© 2019 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).)

The European Union Environmental Footprint (EU-EF) is a harmonized method to measure and communicate the life cycle environmental performance of products and organizations. Among 16 different impact categories included in the EU-EF, 1 focuses on the impact of substances on freshwater ecosystems and requires the use of toxicity data. This paper evaluates the use of the aquatic toxicity data submitted to the EU Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulation. It presents an automated computerized approach for selecting substance ecotoxicity values, building on a set of quality and reliability criteria to extract the most relevant data points for calculating the substance specific hazard values. A selected set of criteria led to the exclusion of approximately 82% of the original REACH ecotoxicological data available as of May 2015 due to incomplete initial encoding of the data by the REACH registrant, missing information such as duration of exposure, endpoint measured, species tested, and imprecise toxicity values (i.e., reported with greater than or less than signs). From an initial set of 305 068 ecotoxicity data records available in the REACH database, the final usable database contains 54 353 toxicity records (29 421 characterized as acute and 24 941 as chronic) covering 9 taxonomic groups, with algae, crustaceans, and fish representing 93% of the data. This data set is valuable for assessing the environmental toxicity of the substance contained whether through traditional substance risk assessment, product toxicity labeling, life cycle assessment (LCA) or environmental impact assessment approaches. However, the resulting loss of approximately 82% of the data suggests that changes in procedures used to generate, report, and document the data within REACH are needed to improve data utility for the various assessment approaches. The rules used to select the data to be used are the primary focus of this article. Integr Environ Assess Manag 2019;15:783-795. © 2019 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC)., (© 2019 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).)

Mercury (Hg) is a neurotoxin that can cause debilitating effects to human and environmental receptors under high exposure conditions. For industrial and municipal point sources that discharge Hg, wastewater limitations on total Hg (THg) concentrations or loads are typical. While this regulatory practice provides simplicity for regulated industry and water resource agencies (i.e., for analytical detection and reporting purposes), it ignores the important considerations of speciation and bioavailability. In this study, water samples were collected from multiple power plant wastewater, simulated mixing zone, and ambient river locations (N = 10 to 20) and were analyzed for bioavailable Hg forms (methylmercury and acid-labile Hg, or BHg), THg, and dissolved Hg. The median concentration of THg in wastewater, mixing zone, and ambient river samples was 7.1, 5.3, and 2.3 ng/L, respectively. The percentages of THg as BHg (median values) were 18.7%, 29.3%, and 8.5% for wastewater, mixing zone, and ambient river samples. The percentages of methylmercury (MeHg) as THg were not statistically different between paired ambient and mixing zone samples (P > 0.05); this result indicates that wastewater did not increase the MeHg fraction when mixed with ambient water. Multiple regression analysis indicated that variation in THg for combined wastewater and mixing zone samples could be adequately explained by pooled water quality parameters (total suspended solids, total dissolved solids, sulfate, total organic carbon, pH, specific conductivity; r 2  = 0.51; P < 0.05); however, no significant regression relationships were apparent for the percentage of BHg. These results, at least for the wastewater samples evaluated, indicate that regulating THg is likely overly conservative, and mechanisms to regulate the bioavailable forms of Hg are needed. If Hg fish tissue monitoring data indicate that concentrations are less than consumption thresholds, metal translator methodologies or bioavailability-based criterion techniques (as currently used for non-Hg trace elements) should be allowed for Hg. Integr Environ Assess Manag 2019;15:142-147. © 2018 SETAC., (© 2018 SETAC.)

The European Marine Strategy Framework Directive and the United States Microbead Free Waters Act are credited for being ambitious in their goals for protecting the marine environment from microplastics pollution. As a result, the microplastic pollution of marine environments and the incidence of microplastic ingestion by fish is rapidly receiving an increase in overdue attention. This commentary summarizes recent discoveries regarding the potential negative effects of micro- and nanoplastic ingestion by fish. Analysis shows that the occurrence of microplastics in the gastrointestinal tract of fish is ephemeral, with low accumulation potential in the gastrointestinal tract, although translocation to the liver may occur. Nevertheless, the total load of micro- and nanoplastics that will pass through the gastrointestinal tract of a fish in its lifetime is likely high and will keep increasing in the future. This may pose a risk because there is evidence that micro- and nanoplastic ingestion can interfere with fish health. Observed effects of microplastics ingestion include (but are not necessarily limited to) intestinal blockage, physical damage, histopathological alterations in the intestines, change in behavior, change in lipid metabolism, and transfer to the liver. Integr Environ Assess Manag 2017;13:510-515. © 2017 SETAC., (© 2017 SETAC.)

We investigated the appropriateness of several methods, including those recommended in the Aquatic Guidance Document of the European Food Safety Authority (EFSA), for the derivation of chronic Tier-1 regulatory acceptable concentrations (RACs) for insecticides and aquatic organisms. The insecticides represented different chemical classes (organophosphates, pyrethroids, benzoylureas, insect growth regulators, biopesticides, carbamates, neonicotinoids, and miscellaneous). Chronic Tier-1 RACs derived using toxicity data for the standard species Daphnia magna, Chironomus spp., and/or Americamysis bahia, were compared with Tier-3 RACs derived from micro- and mesocosm studies on basis of the ecological threshold option (ETO-RACs). ETO-RACs could be derived for 31 insecticides applied to micro- and mesocosms in single or multiple applications, yielding a total number of 36 cases for comparison. The chronic Tier-1 RACs calculated according to the EFSA approach resulted in a sufficient protection level, except for 1 neonicotinoid (slightly underprotective) and for several pyrethroids if toxicity data for A. bahia were not included. This latter observation can be explained by 1) the fact that A. bahia is the most sensitive standard test species for pyrethroids, 2) the hydrophobic properties of pyrethroids, and 3) the fact that long-term effects observed in (epi) benthic arthropods may be better explained by exposure via the sediment than via overlying water. Besides including toxicity data for A. bahia, the protection level for pyrethroids can be improved by selecting both D. magna and Chironomus spp. as standard test species for chronic Tier-1 derivation. Although protective in the majority of cases, the conservativeness of the recommended chronic Tier-1 RACs appears to be less than an order of magnitude for a relatively large proportion of insecticides when compared with their Tier-3 ETO-RACs. This may leave limited options for refinement of the chronic effect assessment using laboratory toxicity data for additional species. Integr Environ Assess Manag 2016;12:747-758. © 2015 SETAC., (© 2015 SETAC.)