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2 results on '"Blindness, Cortical drug therapy"'

1. Clinical, electrophysiological and brain imaging features during recurrent ictal cortical blindness associated with chronic liver failure.

Author

van Pesch V, Hernalsteen D, van Rijckevorsel K, Duprez T, Boschi A, Ivanoiu A, and Sindic CJ

Subjects
Anticonvulsants therapeutic use, Blindness, Cortical drug therapy, Blindness, Cortical physiopathology, Brain Edema drug therapy, Brain Edema etiology, Brain Edema physiopathology, Chronic Disease, Electroencephalography, Fatal Outcome, Female, Hepatic Encephalopathy physiopathology, Humans, Magnetic Resonance Imaging, Middle Aged, Recurrence, Status Epilepticus drug therapy, Status Epilepticus physiopathology, Visual Cortex drug effects, Visual Cortex physiopathology, Blindness, Cortical etiology, Hepatic Encephalopathy complications, Liver Failure complications, Status Epilepticus complications
Abstract

Transient neuroimaging features indicating primary cortical and secondary subcortical white matter cytotoxic oedema have been described in association with prolonged or intense seizures. We describe the unusual condition of recurrent ictal cortical blindness due to focal occipital status epilepticus, in the context of chronic hepatic failure. There was a close association between the onset and disappearance of clinical, electrophysiological and magnetic resonance imaging abnormalities.

Published
2006

2. A case of Churg-Strauss syndrome presenting with cortical blindness.

Author

Dinç A, Soy M, Pay S, Simsek I, Erdem H, and Sobaci G

Subjects
Administration, Oral, Anti-Inflammatory Agents administration & dosage, Blindness, Cortical diagnosis, Blindness, Cortical drug therapy, Cerebral Infarction complications, Churg-Strauss Syndrome diagnosis, Churg-Strauss Syndrome drug therapy, Cyclophosphamide administration & dosage, Female, Follow-Up Studies, Humans, Immunosuppressive Agents administration & dosage, Magnetic Resonance Imaging, Middle Aged, Occipital Lobe, Prednisolone administration & dosage, Time Factors, Tomography, X-Ray Computed, Visual Acuity, Blindness, Cortical etiology, Churg-Strauss Syndrome complications
Abstract

A 46-year-old woman with a sudden sight loss due to infarction of the occipital lobes is reported. The association of pulmonary disease, digital ischaemia, polyneuropathy and peripheral eosinophilia led to a diagnosis of Churg-Strauss syndrome. Her vision partially improved by a treatment with steroids and monthly i.v. cyclophosphamide. To our knowledge, this is the first case of CSS with a sudden loss of vision due to bilateral occipital infarction.

Published
2000
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