1. Aspergillus fumigatus cranial infection after accidental traumatism.
- Author
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Rodríguez-Hernández MJ, Jiménez-Mejías ME, Montero JM, Regordan C, and Ferreras G
- Subjects
- Adult, Aspergillus fumigatus drug effects, Combined Modality Therapy, Debridement methods, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Injury Severity Score, Treatment Outcome, Wound Healing drug effects, Wound Healing physiology, Amphotericin B administration & dosage, Aspergillosis diagnosis, Aspergillosis therapy, Aspergillus fumigatus isolation & purification, Itraconazole administration & dosage, Skull injuries
- Abstract
Described here is a case of Aspergillus fumigatus cranial infection secondary to accidental cranial traumatism that occurred in an immunocompetent patient and the questions that arose concerning treatment. No reports of post-traumatic cranial osteomyelitis caused by Aspergillus spp. and the ideal treatment to be followed have yet been described in the literature. In the present case, surgical debridement of the wound followed by treatment with 1 mg/kg/iv/day of amphotericin B for 21 days and then 200 mg/vo/12 h of itraconazole for 6 months obtained good results.
- Published
- 2001
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