1. Genetic Basis of Endocrine Regulation of Spermatogenesis
- Author
-
Edmund Y. Ko and Julie W. Cheng
- Subjects
medicine.medical_specialty ,medicine.drug_class ,Biology ,Sertoli cell ,Androgen receptor ,medicine.anatomical_structure ,Endocrinology ,Estrogen ,Internal medicine ,medicine ,Endocrine system ,Spermatogenesis ,Testosterone ,Function (biology) ,Hormone - Abstract
Hormonal regulation contributes significantly to spermatogenesis through interactions between the hypothalamic-pituitary-gonadal axis, testosterone synthesis, Sertoli cell function, androgen receptor, and other hormonal influences, such as estrogen. Congenital or acquired causes of endocrine dysfunction can affect spermatogenesis and male fertility. The purpose of this chapter is to discuss the endocrine regulation of spermatogenesis with consideration of its genetic basis.
- Published
- 2020