1. Effect of polyol chemistry on the in vitro biostability of segmented polyurethanes
- Author
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Stuart L. Cooper, Atsushi Takahara, Arthur J. Coury, and Robert W. Hergenrother
- Subjects
chemistry.chemical_classification ,Hydrolysis ,chemistry.chemical_compound ,Polyol ,X-ray photoelectron spectroscopy ,Chemical engineering ,Chemistry ,Attenuated total reflection ,Polymer chemistry ,Infrared spectroscopy ,Sorption ,Ether ,Bond cleavage - Abstract
A series of segmented polyurethanes (SPU’s) containing various polyol soft segments was prepared and their resistance to oxidative degradation, hydrolysis, and lipid sorption was investigated. The SPU with the polyether soft segment showed a large reduction in mechanical strength after exposure to the oxidative environment. Surface cracking was often observed in these specimens. X-ray photoelection spectroscopy (XPS) and Fourier transform attenuated total reflection infrared spectroscopy (FT ATR-IR) measurements revealed that scission of the ether linkage occurs upon oxidation. The stability of SPU’s against hydrolysis depended on the hydrophilicity of the soft segment component. The SPU with a poly(dimethylsiloxane) soft segment showed extensive reduction in strength after lipid sorption.
- Published
- 1991
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