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Trichoscopic examination of the scalp may be helpful in the diagnosis and differential diagnosis of alopecic and nonalopecic conditions related to systemic lymphoproliferative diseases, particularly follicular mucinosis, folliculotropic mycosis fungoides, and multiple myeloma with monoclonal dysproteinemia.

Hair loss and scalp lesions may accompany several systemic disorders, such as metabolic abnormalities, endocrine conditions, autoimmune diseases, nutritional deficiencies, internal malignancy, and hematologic diseases. Hair problems may be the initial complaint causing patients to seek medical assistance. Thus, when performing trichoscopy, dermatologists should maintain a high index of suspicion when patients present with unexplained trichologic complaints.